Search Results - "Potter, Catherine"

Downstream processing of a ternary amorphous solid dispersion: The impacts of spray drying and hot melt extrusion on powder flow, compression and dissolution by Davis, Mark T., Potter, Catherine B., Walker, Gavin M.

“…[Display omitted] Downstream processing aspects of a stable form of amorphous itraconazole exhibiting enhanced dissolution properties were studied. Preparation…”
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Design of spray dried ternary solid dispersions comprising itraconazole, soluplus and HPMCP: Effect of constituent compositions by Davis, Mark T., Potter, Catherine B., Mohammadpour, Maryam, Albadarin, Ahmad B., Walker, Gavin M.

“…[Display omitted] A range of 17 ternary formulations of itraconazole (ITZ), HPMCP and Soluplus have been manufactured using spray drying. These amorphous solid…”
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Development of stability-enhanced ternary solid dispersions via combinations of HPMCP and Soluplus® processed by hot melt extrusion by Albadarin, Ahmad B., Potter, Catherine B., Davis, Mark T., Iqbal, Javed, Korde, Sachin, Pagire, Sudhir, Paradkar, Anant, Walker, Gavin

“…[Display omitted] The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose phthalate (HPMCP-HP-50) and Soluplus® polymers for…”
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Measuring child coping in times of societal crises: Pilot development, reliability, as well as mental health and meaning mindset convergent validity of the children’s crisis coping scale (3Cs) by Armstrong, Laura L., Potter, Catherine L.

“…To date, there are no brief child self-report coping measures for the pandemic and other major societal events resulting in social or learning disruptions for…”
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Investigation of the Dependence of the Flory–Huggins Interaction Parameter on Temperature and Composition in a Drug–Polymer System by Potter, Catherine B, Davis, Mark T, Albadarin, Ahmad B, Walker, Gavin M

“…The Flory–Huggins (F–H) solubility equation has been widely used to describe the solubility of a small-molecule drug in a polymeric carrier and thus determine…”
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Investigation of polymorphic transitions of piracetam induced during wet granulation by Potter, Catherine B., Kollamaram, Gayathri, Zeglinski, Jacek, Whitaker, Darren A., Croker, Denise M., Walker, Gavin M.

“…[Display omitted] Piracetam was investigated as a model API which is known to exhibit a number of different polymorphic forms. It is freely soluble in water so…”
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Influence of DNMT genotype on global and site specific DNA methylation patterns in neonates and pregnant women by Potter, Catherine, McKay, Jill, Groom, Alexandra, Ford, Dianne, Coneyworth, Lisa, Mathers, John C, Relton, Caroline L

“…This study examines the relationship between common genetic variation within DNA methyltransferase genes and inter-individual variation in DNA methylation…”
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Genetic and non-genetic influences during pregnancy on infant global and site specific DNA methylation: role for folate gene variants and vitamin B12 by McKay, Jill A, Groom, Alexandra, Potter, Catherine, Coneyworth, Lisa J, Ford, Dianne, Mathers, John C, Relton, Caroline L

“…Inter-individual variation in patterns of DNA methylation at birth can be explained by the influence of environmental, genetic and stochastic factors. This…”
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Use of ultrasound imaging by physiotherapists: A pilot study to survey use, skills and training by Potter, Catherine L, Cairns, Mindy C, Stokes, Maria

“…Abstract Objective This study aimed to design and pilot a questionnaire to survey the use of ultrasound imaging (USI) by physiotherapists in the United Kingdom…”
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Amorphous solid dispersion of ibuprofen: A comparative study on the effect of solution based techniques by Ziaee, Ahmad, O'Dea, Stephen, Howard-Hildige, Aoise, Padrela, Luis, Potter, Catherine, Iqbal, Javed, Albadarin, Ahmad B., Walker, Gavin, O'Reilly, Emmet J.

“…[Display omitted] Amorphous solid dispersion (ASD) is one of the most promising strategies for improving the solubility of active pharmaceutical ingredients…”
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Probing the Effects of Experimental Conditions on the Character of Drug-Polymer Phase Diagrams Constructed Using Flory-Huggins Theory by Donnelly, Conor, Tian, Yiwei, Potter, Catherine, Jones, David S., Andrews, Gavin P.

“…Purpose Amorphous drug-polymer solid dispersions have been found to result in improved drug dissolution rates when compared to their crystalline counterparts…”
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Genome‐wide association study of genetic predictors of anti–tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci by Plant, Darren, Bowes, John, Potter, Catherine, Hyrich, Kimme L., Morgan, Ann W., Wilson, Anthony G., Isaacs, John D., Barton, Anne

“…Objective Anti–tumor necrosis factor (anti‐TNF) agents are successful therapies in rheumatoid arthritis (RA); however, inadequate response occurs in 30–40% of…”
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Establishing a Regional Health System and Community-Based Organization Social Care Coordination Network: An Application of Geospatial Analysis by Fitzpatrick, Stephanie L, Banegas, Matthew P, Mosen, David M, Voelkel, Jackson L, Keast, Erin M, Betcher, Akiko, Potter, Catherine

“…Adverse social determinants of health have been shown to be associated with a greater chance of developing chronic conditions. Although there has been…”
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Epigenetic Epidemiology. Karin B. Michels (ed) by Potter, Catherine, Relton, Caroline L

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Novel Supercritical Carbon Dioxide Impregnation Technique for the Production of Amorphous Solid Drug Dispersions: A Comparison to Hot Melt Extrusion by Potter, Catherine, Tian, Yiwei, Walker, Gavin, McCoy, Colin, Hornsby, Peter, Donnelly, Conor, Jones, David S, Andrews, Gavin P

“…The formulation of BCS Class II drugs as amorphous solid dispersions has been shown to provide advantages with respect to improving the aqueous solubility of…”
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Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up by Houseman, Mark, Potter, Catherine, Marshall, Nicola, Lakey, Rachel, Cawston, Tim, Griffiths, Ian, Young-Min, Steven, Isaacs, John D

“…At present, there is no reliable tool for predicting disease outcome in patients with rheumatoid arthritis (RA). We previously demonstrated an association…”
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Maternal Red Blood Cell Folate and Infant Vitamin B 12 Status Influence Methylation of Genes Associated with Childhood Acute Lymphoblastic Leukemia by Potter, Catherine, Moorman, Anthony Vincent, Relton, Caroline Laura, Ford, Dianne, Mathers, John Cummings, Strathdee, Gordon, McKay, Jill Ann

“…Inadequate maternal folate intake is associated with increased childhood acute lymphoblastic leukemia (ALL) risk. Folate provides methyl groups for DNA…”
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Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles by PEARCE, Mark S, MCCONNELL, James C, POTTER, Catherine, BARRETT, Laura M, PARKER, Louise, MATHERS, John C, RELTON, Caroline L

“…Patterns of DNA methylation change with age and these changes are believed to be associated with the development of common complex diseases. The hypothesis…”
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Maternal Red Blood Cell Folate and Infant Vitamin B12 Status Influence Methylation of Genes Associated with Childhood Acute Lymphoblastic Leukemia by Potter, Catherine, Moorman, Anthony Vincent, Relton, Caroline Laura, Ford, Dianne, Mathers, John Cummings, Strathdee, Gordon, McKay, Jill Ann

“…Scope Inadequate maternal folate intake is associated with increased childhood acute lymphoblastic leukemia (ALL) risk. Folate provides methyl groups for DNA…”
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Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis by Maxwell, James R., Potter, Catherine, Hyrich, Kimme L., Barton, Anne, Worthington, Jane, Isaacs, John D., Morgan, Ann W., Wilson, Anthony G.

“…Anti-tumour necrosis factor (TNF) agents have revolutionized the treatment of patients with rheumatoid arthritis (RA). These therapies are, however, expensive…”
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