Search Results - "Pots, Jeanette"

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells by Schreibelt, Gerty, Bol, Kalijn F, Westdorp, Harm, Wimmers, Florian, Aarntzen, Erik H J G, Duiveman-de Boer, Tjitske, van de Rakt, Mandy W M M, Scharenborg, Nicole M, de Boer, Annemiek J, Pots, Jeanette M, Olde Nordkamp, Michel A M, van Oorschot, Tom G M, Tel, Jurjen, Winkels, Gregor, Petry, Katja, Blokx, Willeke A M, van Rossum, Michelle M, Welzen, Marieke E B, Mus, Roel D M, Croockewit, Sandra A J, Koornstra, Rutger H T, Jacobs, Joannes F M, Kelderman, Sander, Blank, Christian U, Gerritsen, Winald R, Punt, Cornelis J A, Figdor, Carl G, de Vries, I Jolanda M

“…Thus far, dendritic cell (DC)-based immunotherapy of cancer was primarily based on in vitro-generated monocyte-derived DCs, which require extensive in vitro…”
Get full text

Comparison of antibodies and carbohydrates to target vaccines to human dendritic cells via DC-SIGN by Cruz, Luis J, Tacken, Paul J, Pots, Jeanette M, Torensma, Ruurd, Buschow, Sonja I, Figdor, Carl G

“…Abstract Vaccine efficacy is improved upon specific delivery to professional antigen (Ag) presenting cells, such as dendritic cells (DCs). Antigenicity and…”
Get full text

Fully closed and automated enrichment of primary blood dendritic cells for cancer immunotherapy by Schreibelt, Gerty, Duiveman-de Boer, Tjitske, Pots, Jeanette M, van Oorschot, Tom G M, de Boer, Annemiek J, Scharenborg, Nicole M, van de Rakt, Mandy W M M, Bos, Kevin, de Goede, Anna L, Petry, Katja, Brüning, Mareke, Angerer, Caroline, Schöggl, Carola, Dzionek, Andreas, de Vries, I Jolanda M

“…Dendritic cell (DC) vaccination is a promising approach to induce tumor-specific immune responses in cancer patients. Until recently, most DC vaccines were…”
Get full text

Translating the Manufacture of Immunotherapeutic PLGA Nanoparticles from Lab to Industrial Scale: Process Transfer and In Vitro Testing by Operti, Maria Camilla, Bernhardt, Alexander, Pots, Jeanette, Sincari, Vladimir, Jager, Eliezer, Grimm, Silko, Engel, Andrea, Benedikt, Anne, Hrubý, Martin, De Vries, Ingrid Jolanda M, Figdor, Carl G, Tagit, Oya

“…Poly(lactic-co-glycolic acid) (PLGA) nanoparticle-based drug delivery systems are known to offer a plethora of potential therapeutic benefits. However,…”
Get full text

Cytokine analysis as a tool to understand tumour–host interaction in ovarian cancer by Yigit, Refika, Figdor, Carl G, Zusterzeel, Petra L.M, Pots, Jeanette M, Torensma, Ruurd, Massuger, Leon F.A.G

“…Abstract Epithelial ovarian cancer (EOC) is an immunogenic tumour and exploits many suppressive ways to escape immune eradication. EOC is known to spread…”
Get full text

Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients by Bol, Kalijn F, Figdor, Carl G, Aarntzen, Erik HJG, Welzen, Marieke EB, van Rossum, Michelle M, Blokx, Willeke AM, van de Rakt, Mandy WMM, Scharenborg, Nicole M, de Boer, Annemiek J, Pots, Jeanette M, olde Nordkamp, Michel AM, van Oorschot, Tom GM, Mus, Roel DM, Croockewit, Sandra AJ, Jacobs, Joannes FM, Schuler, Gerold, Neyns, Bart, Austyn, Jonathan M, Punt, Cornelis JA, Schreibelt, Gerty, de Vries, I Jolanda M

“…Autologous dendritic cell (DC) therapy is an experimental cellular immunotherapy that is safe and immunogenic in patients with advanced melanoma. In an attempt…”
Get full text

Successful generation of primary virus-specific and anti-tumor T-cell responses from the naïve donor T-cell repertoire is determined by the balance between antigen-specific precursor T cells and regulatory T cells by JEDEMA, Inge, VAN DE MEENT, Marian, POTS, Jeanette, KESTER, Michel G. D, VAN DER BEEK, Martha T, FALKENBURG, J. H. Frederik

“…One of the major challenges in allogeneic stem cell transplantation is to find a balance between the harmful induction of graft-versus-host disease and the…”
Get full text

Humoral and cellular immune responses after influenza vaccination in patients with chronic fatigue syndrome by Prinsen, Hetty, de Vries, I Jolanda M, Torensma, Ruurd, Pots, Jeanette M, Mulder, Sasja F, van Herpen, Carla M L, Elving, Lammy D, Bleijenberg, Gijs, Stelma, Foekje F, van Laarhoven, Hanneke W M

“…Chronic fatigue syndrome (CFS) is a clinical condition characterized by severe and disabling fatigue that is medically unexplained and lasts longer than 6…”
Get full text

Humoral and cellular immune responses after influenza vaccination in patients with postcancer fatigue by Prinsen, Hetty, van Laarhoven, Hanneke WM, Pots, Jeanette M, Duiveman-de Boer, Tjitske, Mulder, Sasja F, van Herpen, Carla ML, Jacobs, Joannes FM, Leer, Jan Willem H, Bleijenberg, Gijs, Stelma, Foekje F, Torensma, Ruurd, de Vries, I Jolanda M

“…The aim of this study was to compare humoral and cellular immune responses to influenza vaccination in cancer survivors with and without severe symptoms of…”
Get full text

Sequence Analysis of the Structural Nuclear Encoded Subunits and Assembly Genes of Cytochrome c Oxidase in a Cohort of 10 Isolated Complex IV—Deficient Patients Revealed Five Mutations by Coenen, Marieke J.H., Smeitink, Jan A.M., Pots, Jeanette M., van Kaauwen, Edwin, Trijbels, Frans J.M., Hol, Frans A., van den Heuvel, Lambert P.

“…The mitochondrial oxidative phosphorylation system is composed of five multiprotein complexes. The fourth complex of this system, cytochrome c oxidase (complex…”
Get full text

Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity by Bol, Kalijn F., Aarntzen, Erik H. J. G., Pots, Jeanette M., Olde Nordkamp, Michel A. M., van de Rakt, Mandy W. M. M., Scharenborg, Nicole M., de Boer, Annemiek J., van Oorschot, Tom G. M., Croockewit, Sandra A. J., Blokx, Willeke A. M., Oyen, Wim J. G., Boerman, Otto C., Mus, Roel D. M., van Rossum, Michelle M., van der Graaf, Chantal A. A., Punt, Cornelis J. A., Adema, Gosse J., Figdor, Carl G., de Vries, I. Jolanda M., Schreibelt, Gerty

“…Dendritic cell (DC)-based immunotherapy is explored worldwide in cancer patients, predominantly with DC matured with pro-inflammatory cytokines and…”
Get full text

Both the Activation Kinetics and the Frequency of Regulatory T Cells Determine the Ability to Generate Primary Anti-Tumor and Pathogen- Specific Immune Responses from a Naïve Donor T Cell Repertoire by Jedema, Inge, Pots, Jeanette, van de Meent, Marian, Willemze, Roel, Falkenburg, J.H. Frederik

“…Allogeneic stem cell transplantation (allo-SCT) is commonly used in the treatment of patients with hematological malignancies. However, the impaired immune…”
Get full text

Both the Activation Kinetics and the Frequency of Regulatory T Cells Determine the Ability to Generate Primary Anti-Tumor and Pathogen- Specific Immune Responses from a Naïve Donor T Cell Repertoire by Jedema, Inge, Pots, Jeanette, van de Meent, Marian, Willemze, Roel, Falkenburg, J.H. Frederik

“…Abstract Allogeneic stem cell transplantation (allo-SCT) is commonly used in the treatment of patients with hematological malignancies. However, the impaired…”
Get full text

Cytokine profiles in cyst fluids from ovarian tumors reflect immunosuppressive state of the tumor by Yigit, Refika, Massuger, Leon F A G, Zusterzeel, Petra L M, Pots, Jeanette, Figdor, Carl G, Torensma, Ruurd

“…Ovarian tumors, both benign and malignant, often contain cystic lesions. Analysis of cytokine levels of this enclosed fluid may be a pure way to study cytokine…”
Get more information