Search Results - "Potočnjak, Iva"
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Carvacrol attenuates acute kidney injury induced by cisplatin through suppression of ERK and PI3K/Akt activation
Published in Food and chemical toxicology (01-12-2016)“…We investigated the mechanisms of renoprotective effects of carvacrol, a monoterpenoid compound, against cisplatin (CP)-induced kidney injury. Male BALB/cN…”
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A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives
Published in Archives of toxicology (01-01-2016)“…Hepatoprotective effects of natural compounds have been frequently attributed to their antioxidant properties and the ability to mobilize endogenous…”
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Luteolin ameliorates experimental colitis in mice through ERK-mediated suppression of inflammation, apoptosis and autophagy
Published in Food and chemical toxicology (01-11-2020)“…Ulcerative colitis (UC) is a chronic inflammatory disease with increasing incidence and prevalence worldwide. Currently used treatments of UC are…”
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Carvacrol induces cytotoxicity in human cervical cancer cells but causes cisplatin resistance: Involvement of MEK–ERK activation
Published in Phytotherapy research (01-06-2018)“…Carvacrol has been shown to possess anticancer activity, but the mechanism is unknown, as well as the possibility of interaction with anticancer drugs. The aim…”
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5
Chlorogenic acid ameliorates experimental colitis in mice by suppressing signaling pathways involved in inflammatory response and apoptosis
Published in Food and chemical toxicology (01-11-2018)“…Chlorogenic acid (ChA) exhibits a multitude of positive health effects, however, the signaling mechanisms by which ChA could influence the inflammatory…”
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Oleanolic acid attenuates cisplatin-induced nephrotoxicity in mice and chemosensitizes human cervical cancer cells to cisplatin cytotoxicity
Published in Food and chemical toxicology (01-10-2019)“…Oleanolic acid (OA) is a natural triterpenoid that possesses numerous beneficial health effects such as antioxidant, anti-inflammatory and anti-apoptotic…”
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Antitumor activity of luteolin in human colon cancer SW620 cells is mediated by the ERK/FOXO3a signaling pathway
Published in Toxicology in vitro (01-08-2020)“…The aim of this study was to investigate the mechanism of the anticancer activity of luteolin in metastatic human colon cancer SW620 cells. Luteolin…”
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Oleanolic acid induces HCT116 colon cancer cell death through the p38/FOXO3a/Sirt6 pathway
Published in Chemico-biological interactions (25-08-2022)“…Oleanolic acid (OA) is a natural compound that possesses numerous beneficial health effects, including anticancer activity. The current study aimed to…”
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Sinomenine mitigates cisplatin-induced kidney injury by targeting multiple signaling pathways
Published in Food and chemical toxicology (01-01-2023)“…Sinomenine is a pharmacologically active alkaloid with antioxidant and anti-inflammatory properties. We aimed to investigate the mechanism of renoprotective…”
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Stevia and stevioside protect against cisplatin nephrotoxicity through inhibition of ERK1/2, STAT3, and NF-κB activation
Published in Food and chemical toxicology (01-09-2017)“…We investigated the effect of natural sweetener Stevia rebaudiana and its constituent stevioside in cisplatin (CP)-induced kidney injury. Male BALB/cN mice…”
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Nephroprotective activities of rosmarinic acid against cisplatin-induced kidney injury in mice
Published in Food and chemical toxicology (01-04-2014)“…•Rosmarinic acid ameliorated increased serum creatinine and blood urea nitrogen in cisplatin-intoxicated mice.•The increase in renal 4-hydroxynonenal,…”
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Oral administration of oleuropein attenuates cisplatin‐induced acute renal injury in mice through inhibition of ERK signaling
Published in Molecular nutrition & food research (01-03-2016)“…SCOPE: Oleuropein possesses numerous health beneficial effects. We investigated the renoprotective effects of oleuropein against cisplatin (CP) induced kidney…”
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Terminalia bellerica aerial parts ethyl acetate extract exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice
Published in Journal of functional foods (01-05-2014)“…•The antioxidant potential of Terminalia bellerica aerial parts extracts was determined.•T. bellerica ethyl acetate (TBE) extract had the highest…”
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Aucubin administered by either oral or parenteral route protects against cisplatin-induced acute kidney injury in mice
Published in Food and chemical toxicology (01-08-2020)“…Aucubin is pharmacologically active natural compound which possesses numerous beneficial properties. This study aimed to evaluate the protective effect of…”
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Antitumour activity of luteolin in human colon cancer SW620 cells is mediated by the ERK/FOXO3a signalling pathway
Published in Arhiv za higijenu rada i toksikologiju (01-01-2021)Get full text
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Aucubin administered by either oral or parenteral route protects against cisplatin-induced acute kidney injury in mice
Published in Arhiv za higijenu rada i toksikologiju (01-01-2021)Get full text
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