Search Results - "Potkin, Steven G."

Clinical Guidance on the Identification and Management of Treatment-Resistant Schizophrenia by Kane, John M, Agid, Ofer, Baldwin, Marjorie L, Howes, Oliver, Lindenmayer, Jean-Pierre, Marder, Stephen, Olfson, Mark, Potkin, Steven G, Correll, Christoph U

“…Treatment-resistant schizophrenia (TRS) occurs in approximately 30% of individuals diagnosed with schizophrenia. The identification and management of TRS in…”
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Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP by Doran, Eric, Keator, David, Head, Elizabeth, Phelan, Michael J, Kim, Ron, Totoiu, Minodora, Barrio, Jorge R, Small, Gary W, Potkin, Steven G, Lott, Ira T

“…Overexpression of the amyloid precursor protein (APP) gene on chromosome 21 in Down syndrome (DS) has been linked to increased brain amyloid levels and…”
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Qualify: a randomized head-to-head study of aripiprazole once-monthly and paliperidone palmitate in the treatment of schizophrenia by Naber, Dieter, Hansen, Karina, Forray, Carlos, Baker, Ross A, Sapin, Christophe, Beillat, Maud, Peters-Strickland, Timothy, Nylander, Anna-Greta, Hertel, Peter, Andersen, Henrik Steen, Eramo, Anna, Loze, Jean-Yves, Potkin, Steven G

“…Abstract Objective To directly compare aripiprazole once-monthly 400 mg (AOM 400) and paliperidone palmitate once-monthly (PP) on the Heinrichs–Carpenter…”
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Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease by Potkin, Steven G, Guffanti, Guia, Lakatos, Anita, Turner, Jessica A, Kruggel, Frithjof, Fallon, James H, Saykin, Andrew J, Orro, Alessandro, Lupoli, Sara, Salvi, Erika, Weiner, Michael, Macciardi, Fabio

“…With the exception of APOE epsilon4 allele, the common genetic risk factors for sporadic Alzheimer's Disease (AD) are unknown. We completed a genome-wide…”
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Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion by Sui, Jing, Qi, Shile, van Erp, Theo G. M., Bustillo, Juan, Jiang, Rongtao, Lin, Dongdong, Turner, Jessica A., Damaraju, Eswar, Mayer, Andrew R., Cui, Yue, Fu, Zening, Du, Yuhui, Chen, Jiayu, Potkin, Steven G., Preda, Adrian, Mathalon, Daniel H., Ford, Judith M., Voyvodic, James, Mueller, Bryon A., Belger, Aysenil, McEwen, Sarah C., O’Leary, Daniel S., McMahon, Agnes, Jiang, Tianzi, Calhoun, Vince D.

“…Cognitive impairment is a feature of many psychiatric diseases, including schizophrenia. Here we aim to identify multimodal biomarkers for quantifying and…”
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Salience-Default Mode Functional Network Connectivity Linked to Positive and Negative Symptoms of Schizophrenia by Hare, Stephanie M, Ford, Judith M, Mathalon, Daniel H, Damaraju, Eswar, Bustillo, Juan, Belger, Aysenil, Lee, Hyo Jong, Mueller, Bryon A, Lim, Kelvin O, Brown, Gregory G, Preda, Adrian, van Erp, Theo G M, Potkin, Steven G, Calhoun, Vince D, Turner, Jessica A

“…Schizophrenia is a complex, debilitating mental disorder characterized by wide-ranging symptoms including delusions, hallucinations (so-called positive…”
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Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans by Saykin, Andrew J, Shen, Li, Yao, Xiaohui, Kim, Sungeun, Nho, Kwangsik, Risacher, Shannon L, Ramanan, Vijay K, Foroud, Tatiana M, Faber, Kelley M, Sarwar, Nadeem, Munsie, Leanne M, Hu, Xiaolan, Soares, Holly D, Potkin, Steven G, Thompson, Paul M, Kauwe, John S.K, Kaddurah-Daouk, Rima, Green, Robert C, Toga, Arthur W, Weiner, Michael W

“…Abstract Introduction Genetic data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) have been crucial in advancing the understanding of Alzheimer's…”
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Meta-Regression Analysis of Placebo Response in Antipsychotic Trials, 1970–2010 by Agid, Ofer, Siu, Cynthia O., Potkin, Steven G., Kapur, Shitij, Watsky, Eric, Vanderburg, Douglas, Zipursky, Robert B., Remington, Gary

“…Placebo response has increased over the past few decades, and this temporal effect is explained by an increase of the number of sites per trial and by a…”
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Efficacy and safety of lurasidone 80 mg/day and 160 mg/day in the treatment of schizophrenia: A randomized, double-blind, placebo- and active-controlled trial by Loebel, Antony, Cucchiaro, Josephine, Sarma, Kaushik, Xu, Lei, Hsu, Chuanchieh, Kalali, Amir H, Pikalov, Andrei, Potkin, Steven G

“…Abstract Objective This study was designed to evaluate the short-term efficacy and safety of once-daily lurasidone (80 mg/day and 160 mg/day) in the treatment…”
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SNP-based pathway enrichment analysis for genome-wide association studies by Weng, Lingjie, Macciardi, Fabio, Subramanian, Aravind, Guffanti, Guia, Potkin, Steven G, Yu, Zhaoxia, Xie, Xiaohui

“…Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic…”
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The Function Biomedical Informatics Research Network Data Repository by Keator, David B., van Erp, Theo G.M., Turner, Jessica A., Glover, Gary H., Mueller, Bryon A., Liu, Thomas T., Voyvodic, James T., Rasmussen, Jerod, Calhoun, Vince D., Lee, Hyo Jong, Toga, Arthur W., McEwen, Sarah, Ford, Judith M., Mathalon, Daniel H., Diaz, Michele, O'Leary, Daniel S., Jeremy Bockholt, H., Gadde, Syam, Preda, Adrian, Wible, Cynthia G., Stern, Hal S., Belger, Aysenil, McCarthy, Gregory, Ozyurt, Burak, Potkin, Steven G.

“…The Function Biomedical Informatics Research Network (FBIRN) developed methods and tools for conducting multi-scanner functional magnetic resonance imaging…”
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Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort by Shen, Li, Kim, Sungeun, Risacher, Shannon L., Nho, Kwangsik, Swaminathan, Shanker, West, John D., Foroud, Tatiana, Pankratz, Nathan, Moore, Jason H., Sloan, Chantel D., Huentelman, Matthew J., Craig, David W., DeChairo, Bryan M., Potkin, Steven G., Jack, Clifford R., Weiner, Michael W., Saykin, Andrew J.

“…A genome-wide, whole brain approach to investigate genetic effects on neuroimaging phenotypes for identifying quantitative trait loci is described. The…”
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Converting positive and negative symptom scores between PANSS and SAPS/SANS by van Erp, Theo G.M, Preda, Adrian, Nguyen, Dana, Faziola, Lawrence, Turner, Jessica, Bustillo, Juan, Belger, Aysenil, Lim, Kelvin O, McEwen, Sarah, Voyvodic, James, Mathalon, Daniel H, Ford, Judith, Potkin, Steven G, FBIRN

“…Abstract The Scale for the Assessment of Positive Symptoms (SAPS), the Scale for the Assessment of Negative Symptoms (SANS), and the Positive and Negative…”
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Brown adipose tissue quantification in human neonates using water-fat separated MRI by Rasmussen, Jerod M, Entringer, Sonja, Nguyen, Annie, van Erp, Theo G M, Burns, Joshua, Guijarro, Ana, Oveisi, Fariba, Swanson, James M, Piomelli, Daniele, Wadhwa, Pathik D, Buss, Claudia, Potkin, Steven G

“…There is a major resurgence of interest in brown adipose tissue (BAT) biology, particularly regarding its determinants and consequences in newborns and…”
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Dentate gyrus volume deficit in schizophrenia by Nakahara, Soichiro, Turner, Jessica A, Calhoun, Vince D, Lim, Kelvin O, Mueller, Bryon, Bustillo, Juan R, O'Leary, Daniel S, McEwen, Sarah, Voyvodic, James, Belger, Aysenil, Mathalon, Daniel H, Ford, Judith M, Macciardi, Fabio, Matsumoto, Mitsuyuki, Potkin, Steven G, van Erp, Theo G M

“…Schizophrenia is associated with robust hippocampal volume deficits but subregion volume deficits, their associations with cognition, and contributing genes…”
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A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype by Potkin, Steven G., Turner, Jessica A., Guffanti, Guia, Lakatos, Anita, Fallon, James H., Nguyen, Dana D., Mathalon, Daniel, Ford, Judith, Lauriello, John, Macciardi, Fabio

“…Background: Genome-wide association studies (GWASs) are increasingly used to identify risk genes for complex illnesses including schizophrenia. These studies…”
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Function biomedical informatics research network recommendations for prospective multicenter functional MRI studies by Glover, Gary H., Mueller, Bryon A., Turner, Jessica A., van Erp, Theo G.M., Liu, Thomas T., Greve, Douglas N., Voyvodic, James T., Rasmussen, Jerod, Brown, Gregory G., Keator, David B., Calhoun, Vince D., Lee, Hyo Jong, Ford, Judith M., Mathalon, Daniel H., Diaz, Michele, O'Leary, Daniel S., Gadde, Syam, Preda, Adrian, Lim, Kelvin O., Wible, Cynthia G., Stern, Hal S., Belger, Aysenil, McCarthy, Gregory, Ozyurt, Burak, Potkin, Steven G.

“…This report provides practical recommendations for the design and execution of multicenter functional MRI (MC‐fMRI) studies based on the collective experience…”
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Disrupted network cross talk, hippocampal dysfunction and hallucinations in schizophrenia by Hare, Stephanie M., Law, Alicia S., Ford, Judith M., Mathalon, Daniel H., Ahmadi, Aral, Damaraju, Eswar, Bustillo, Juan, Belger, Aysenil, Lee, Hyo Jong, Mueller, Bryon A., Lim, Kelvin O., Brown, Gregory G., Preda, Adrian, van Erp, Theo G.M., Potkin, Steven G., Calhoun, Vince D., Turner, Jessica A.

“…Hallucinations characterize schizophrenia, with approximately 59% of patients reporting auditory hallucinations and 27% reporting visual hallucinations. Prior…”
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A multi-site resting state fMRI study on the amplitude of low frequency fluctuations in schizophrenia by Turner, Jessica A, Damaraju, Eswar, van Erp, Theo G M, Mathalon, Daniel H, Ford, Judith M, Voyvodic, James, Mueller, Bryon A, Belger, Aysenil, Bustillo, Juan, McEwen, Sarah, Potkin, Steven G, Fbirn, Calhoun, Vince D

“…This multi-site study compares resting state fMRI amplitude of low frequency fluctuations (ALFF) and fractional ALFF (fALFF) between patients with…”
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A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease by Tuszynski, Mark H, Thal, Leon, Pay, Mary, Salmon, David P, U, Hoi Sang, Bakay, Roy, Patel, Piyush, Blesch, Armin, Vahlsing, H Lee, Ho, Gilbert, Tong, Gang, Potkin, Steven G, Fallon, James, Hansen, Lawrence, Mufson, Elliott J, Kordower, Jeffrey H, Gall, Christine, Conner, James

“…Cholinergic neuron loss is a cardinal feature of Alzheimer disease. Nerve growth factor (NGF) stimulates cholinergic function, improves memory and prevents…”
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