Search Results - "Pothakos, Konstantinos"

Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration by Pothakos, Konstantinos, Kurz, Max J, Lau, Yuen-Sum

“…Animal models of Parkinson's disease have been widely used for investigating the mechanisms of neurodegenerative process and for discovering alternative…”
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Genetic Inactivation of Cholinergic C Bouton Output Improves Motor Performance but not Survival in a Mouse Model of Amyotrophic Lateral Sclerosis by Konsolaki, Eleni, Koropouli, Eleftheria, Tsape, Eirini, Pothakos, Konstantinos, Zagoraiou, Laskaro

“…•Genetic inactivation of cholinergic C bouton output does not alter survival.•Genetic inactivation of cholinergic C bouton output improves motor…”
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Peptidergic modulation of motor neuron output via CART signaling at C bouton synapses by Eleftheriadis, Panagiotis E, Pothakos, Konstantinos, Sharples, Simon A, Apostolou, Panagiota E, Mina, Maria, Tetringa, Efstathia, Tsape, Eirini, Miles, Gareth B, Zagoraiou, Laskaro

“…The intensity of muscle contraction, and therefore movement vigor, needs to be adaptable to enable complex motor behaviors. This can be achieved by adjusting…”
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Low-Level Human Equivalent Gestational Lead Exposure Produces Sex-Specific Motor and Coordination Abnormalities and Late-Onset Obesity in Year-Old Mice by Leasure, J. Leigh, Giddabasappa, Anand, Chaney, Shawntay, Johnson, Jerry E., Pothakos, Konstantinos, Lau, Yuen Sum, Fox, Donald A.

“…Background: Low-level developmental lead exposure is linked to cognitive and neurological disorders in children. However, the long-term effects of gestational…”
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Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA−/− ) mice by Pothakos, Konstantinos, Robinson, John K, Gravanis, Iordanis, Marsteller, Douglas A, Dewey, Stephen L, Tsirka, Stella E

“…Abstract Tissue Plasminogen Activator (tPA) is a serine protease expressed in different areas of the mammalian brain. It has been used clinically to dissolve…”
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Endurance exercise promotes cardiorespiratory rehabilitation without neurorestoration in the chronic mouse model of Parkinsonism with severe neurodegeneration by Al-Jarrah, M, Pothakos, K, Novikova, L, Smirnova, I.V, Kurz, M.J, Stehno-Bittel, L, Lau, Y.-S

“…Abstract Physical rehabilitation with endurance exercise for patients with Parkinson’s disease has not been well established, although some clinical and…”
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A chronic mouse model of Parkinson's disease has a reduced gait pattern certainty by Kurz, Max J., Pothakos, Konstantinos, Jamaluddin, Sakeena, Scott-Pandorf, Melissa, Arellano, Chris, Lau, Yuen-Sum

“…The purpose of this investigation was to determine if a chronic Parkinson's disease mouse model will display less certainty in its gait pattern due to basal…”
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Behavioral and neurochemical characterization of tissue plasminogen activator (tPA)-deficient mice by Pothakos, Konstantinos

“…tPA is a serine protease that converts the inactive precursor plasminogen to the active serine protease plasmin. It has been studied extensively for its…”
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