Search Results - "Potgieter, A. Christiaan"
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African horse sickness virus NS4 is a nucleocytoplasmic protein that localizes to PML nuclear bodies
Published in Journal of general virology (01-01-2020)“…African horse sickness virus (AHSV) is the causative agent of the often fatal disease African horse sickness in equids. The non-structural protein NS4 is the…”
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Investigating the Role of African Horse Sickness Virus VP7 Protein Crystalline Particles on Virus Replication and Release
Published in Viruses (01-10-2022)“…African horse sickness is a deadly and highly infectious disease of equids, caused by African horse sickness virus (AHSV). AHSV is one of the most economically…”
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Are Human P[14] Rotavirus Strains the Result of Interspecies Transmissions from Sheep or Other Ungulates That Belong to the Mammalian Order Artiodactyla?
Published in Journal of Virology (01-04-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events
Published in Infection, genetics and evolution (01-04-2019)“…We report the first whole genome constellations of Mozambican rotavirus A strains detected between 2012 and 2013 in the Mavalane General Hospital in Maputo…”
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Characterising Non-Structural Protein NS4 of African Horse Sickness Virus
Published in PloS one (27-04-2015)“…African horse sickness is a serious equid disease caused by the orbivirus African horse sickness virus (AHSV). The virus has ten double-stranded RNA genome…”
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Creation of a Nonspreading Rift Valley Fever Virus
Published in Journal of Virology (01-12-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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wild-type Botrytis cinerea strain co-infected by double-stranded RNA mycoviruses presents hypovirulence-associated traits
Published in Virology journal (02-07-2013)“…BACKGROUND: Botrytis cinerea CCg378 is a wild-type strain infected with two types of double-stranded RNA (dsRNA) mycoviruses and which presents…”
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Structural Insight into African Horsesickness Virus Infection
Published in Journal of Virology (01-08-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Genetic Characterisation of South African and Mozambican Bovine Rotaviruses Reveals a Typical Bovine-like Artiodactyl Constellation Derived through Multiple Reassortment Events
Published in Pathogens (Basel) (12-10-2021)“…This study presents whole genomes of seven bovine rotavirus strains from South Africa and Mozambique. Double-stranded RNA, extracted from stool samples without…”
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Unusual assortment of segments in 2 rare human rotavirus genomes
Published in Emerging infectious diseases (01-05-2010)“…Using full-length genome sequence analysis, we investigated 2 rare G3P[9] human rotavirus strains isolated from children with diarrhea. The genomes were…”
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Rescue of recent virulent and avirulent field strains of bluetongue virus by reverse genetics
Published in PloS one (17-02-2012)“…Since 1998, Bluetongue virus (BTV)-serotypes 1, 2, 4, 9, and 16 have invaded European countries around the Mediterranean Basin. In 2006, a huge BT-outbreak…”
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Chimaeric virus-like particles derived from consensus genome sequences of human rotavirus strains co-circulating in Africa
Published in PloS one (30-09-2014)“…Rotavirus virus-like particles (RV-VLPs) are potential alternative non-live vaccine candidates due to their high immunogenicity. They mimic the natural…”
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Genetic characterisation of novel G29P[14] and G10P[11] rotavirus strains from African buffalo
Published in Infection, genetics and evolution (01-11-2020)“…We report the first description of rotavirus A strains in African buffalo (Syncerus caffer). Following RNA extraction from stool samples, cDNA was prepared,…”
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Molecular characterization of a new botybirnavirus that infects Botrytis cinerea
Published in Archives of virology (01-05-2019)“…Eight different double-stranded RNA (dsRNA) molecules were found in the wild-type fungal strain Botrytis cinerea CCg427. The electrophoretic profile displayed…”
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African horse sickness virus NS4 protein is an important virulence factor and interferes with JAK-STAT signaling during viral infection
Published in Virus research (01-06-2021)“…•African horse sickness virus (AHSV) NS4 is an important virulence factor in horses.•AHSV NS4 suppresses host innate immunity early in infection.•AHSV NS4…”
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Safety and efficacy of inactivated African horse sickness (AHS) vaccine formulated with different adjuvants
Published in Vaccine (21-10-2020)“…•Inflammatory reactions in horses by adjuvant.•Humoral responses by different vaccination routes.•Safety and efficacy of inactivated AHS vaccine.•DIVA…”
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Establishment of different plasmid only-based reverse genetics systems for the recovery of African horse sickness virus
Published in Virology (New York, N.Y.) (01-12-2016)“…Abstract In an effort to simplify and expand the utility of African horse sickness virus (AHSV) reverse genetics, different plasmid-based reverse genetics…”
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African horse sickness virus (AHSV) with a deletion of 77 amino acids in NS3/NS3a protein is not virulent and a safe promising AHS Disabled Infectious Single Animal (DISA) vaccine platform
Published in Vaccine (05-04-2018)“…•Rescue of high virulent AHSV by reverse genetics.•In-frame deletion of 77 codons in genome segment 10 is crucial for virulence.•Safety and protection by AHS…”
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VP2 Exchange and NS3/NS3a Deletion in African Horse Sickness Virus (AHSV) in Development of Disabled Infectious Single Animal Vaccine Candidates for AHSV
Published in Journal of virology (01-09-2015)“…African horse sickness virus (AHSV) is a virus species in the genus Orbivirus of the family Reoviridae. There are nine serotypes of AHSV showing different…”
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Whole genome analyses of African G2, G8, G9, and G12 rotavirus strains using sequence-independent amplification and 454® pyrosequencing
Published in Journal of medical virology (01-11-2011)“…High mortality rates caused by rotaviruses are associated with several strains such as G2, G8, G9, and G12 rotaviruses. Rotaviruses with G9 and G12 genotypes…”
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