Search Results - "Postrach, Daniel"
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Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
Published in Cell stem cell (02-04-2020)“…Colorectal cancer stem cells (CSCs) express Lgr5 and display extensive stem cell-like multipotency and self-renewal and are thought to seed metastatic disease…”
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Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids
Published in Cell stem cell (06-06-2019)“…The deubiquitinating enzyme BAP1 is a tumor suppressor, among others involved in cholangiocarcinoma. BAP1 has many proposed molecular targets, while its…”
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Polylox barcoding reveals haematopoietic stem cell fates realized in vivo
Published in Nature (London) (24-08-2017)“…An artificial recombination locus, Polylox , that can generate hundreds of thousands of individual barcodes is used to trace the fates of haematopoietic stem…”
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Mast cells link immune sensing to antigen-avoidance behaviour
Published in Nature (London) (17-08-2023)“…The physiological functions of mast cells remain largely an enigma. In the context of barrier damage, mast cells are integrated in type 2 immunity and,…”
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