Search Results - "Postol, Edilberto"
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Analysis of the coverage capacity of the StreptInCor candidate vaccine against Streptococcus pyogenes
Published in Vaccine (07-07-2014)“…Highlights • Anti-StreptInCor antibodies are able to bind to several M proteins. • StreptInCor presented bacterial opsonophagocytic and neutralizing…”
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StreptInCor: a candidate vaccine epitope against S. pyogenes infections induces protection in outbred mice
Published in PloS one (08-04-2013)“…Infection with Streptococcus pyogenes (S. pyogenes) can result in several diseases, particularly in children. S. pyogenes M protein is the major virulence…”
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StreptInCor, a Group A Streptococcal Adsorbed Vaccine: Evaluation of Repeated Intramuscular Dose Toxicity Testing in Rats
Published in Frontiers in cardiovascular medicine (11-05-2021)“…Streptococcus pyogenes infections continue to be a worldwide public health problem, causing various diseases in humans, with rheumatic fever and rheumatic…”
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Streptococcus pyogenes strains in Sao Paulo, Brazil: molecular characterization as a basis for StreptInCor coverage capacity analysis
Published in BMC infectious diseases (05-08-2015)“…Several human diseases are caused by Streptococcus pyogenes, ranging from common infections to autoimmunity. Characterization of the most prevalent strains…”
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HLA class II transgenic mice develop a safe and long lasting immune response against StreptInCor, an anti-group A streptococcus vaccine candidate
Published in Vaccine (26-10-2011)“…Highlights ► HLA class II transgenic mice are important model for study the role of human HLA class II molecules in animal model. ► Long lasting immune…”
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Identification of enolase as a laminin-binding protein on the surface of Staphylococcus aureus
Published in Microbes and infection (01-05-2004)“…We have previously demonstrated that Staphylococcus aureus, a highly invasive bacteria, presents a 52-kDa surface protein that mediates its binding to laminin…”
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StreptInCor: a model of anti-Streptococcus pyogenes vaccine reviewed
Published in Autoimmunity highlights (01-12-2013)“…Streptococcus pyogenes infections remain a health problem in multiple countries because of poststreptococcal sequelae, such as rheumatic fever and rheumatic…”
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A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responses
Published in PloS one (11-02-2011)“…T-cell based vaccines against HIV have the goal of limiting both transmission and disease progression by inducing broad and functionally relevant T cell…”
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A vaccine encoding conserved promiscuous HIV CD4 epitopes induces broad T cell responses in mice transgenic to multiple common HLA class II molecules
Published in PloS one (11-06-2010)“…Current HIV vaccine approaches are focused on immunogens encoding whole HIV antigenic proteins that mainly elicit cytotoxic CD8+ responses. Mounting evidence…”
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Diversity of physiological cell reactivity to heat shock protein 60 in different mouse strains
Published in Cell stress & chaperones (01-06-2007)“…Heat shock proteins (Hsp) are families of highly conserved molecules and immunodominant antigens in some infections and in autoimmune diseases. Some reports…”
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Long-term administration of IgG2a anti-NK1.1 monoclonal antibody ameliorates lupus-like disease in NZB/W mice in spite of an early worsening induced by an IgG2a-dependent BAFF/BLyS production
Published in Immunology (01-10-2008)“…The role of natural killer (NK) T cells in the development of lupus-like disease in mice is still controversial. We treated NZB/W mice with anti-NK1.1…”
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Group A Streptococcus Adsorbed Vaccine: Repeated Intramuscular Dose Toxicity Test in Minipigs
Published in Scientific reports (05-07-2019)“…Streptococcus pyogenes infection continues to be a worldwide public health problem causing various diseases in humans and plays an important role in the…”
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Vγ1 γδ T cells regulate type-1/type-2 immune responses and participate in the resistance to infection and development of heart inflammation in Trypanosoma cruzi-infected BALB/c mice
Published in Microbes and infection (01-03-2006)“…Many different cell populations or lineages participate in the resistance to Trypanosoma cruzi infection. γδ T cells may also take part in a network of…”
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A Vaccine against Streptococcus pyogenes: The Potential to Prevent Rheumatic Fever and Rheumatic Heart Disease
Published in American journal of cardiovascular drugs : drugs, devices, and other interventions (01-02-2013)“…Streptococcus pyogenes causes severe, invasive infections such as the sequelae associated with acute rheumatic fever, rheumatic heart disease, acute…”
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B cells modulate T cells so as to favour T helper type 1 and CD8+ T‐cell responses in the acute phase of Trypanosoma cruzi infection
Published in Immunology (01-12-2007)“…Summary In this study, we have evaluated the production of pro‐ and anti‐inflammatory cytokines and the formation of central and effector memory T cells in…”
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V gamma 1 gamma delta T cells regulate type-1/type-2 immune responses and participate in the resistance to infection and development of heart inflammation in Trypanosoma cruzi-infected BALB/c mice
Published in Microbes and infection (01-03-2006)“…Many different cell populations or lineages participate in the resistance to Trypanosoma cruzi infection. gamma delta T cells may also take part in a network…”
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B cells modulate T cells so as to favour T helper type 1 and CD8 super(+) T-cell responses in the acute phase of Trypanosoma cruzi infection
Published in Immunology (01-12-2007)“…In this study, we have evaluated the production of pro- and anti-inflammatory cytokines and the formation of central and effector memory T cells in mice…”
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Antibodies directed to antigens secreted by murine epithelioid macrophages modulate BCG-induced granulomata
Published in Mediators of Inflammation (1993)“…THE authors have previously shown that epithelioid cells isolated from mice secrete a factor, called macrophage deactivating factor (MDF), that promptly…”
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StreptInCor: A Candidate Vaccine Epitope against S. pyogenes Infections Induces Protection in Outbred Mice. e60969
Published in PloS one (01-04-2013)“…Infection with Streptococcus pyogenes (S. pyogenes) can result in several diseases, particularly in children. S. pyogenes M protein is the major virulence…”
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ORIGINAL ARTICLE: Natural killer T cells are required for the development of a superantigen-driven T helper type 2 immune response in mice
Published in Immunology (01-10-2005)“…We show, here, that one single injection or weekly injections of staphylococcal enterotoxin B (SEB), starting in 1-day-old newborn mice, induced a powerful…”
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