Search Results - "Postmus, Annemarieke G. J."

Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization by Butini, Stefania, Grether, Uwe, Jung, Kwang-Mook, Ligresti, Alessia, Allarà, Marco, Postmus, Annemarieke G. J., Maramai, Samuele, Brogi, Simone, Papa, Alessandro, Carullo, Gabriele, Sykes, David, Veprintsev, Dmitry, Federico, Stefano, Grillo, Alessandro, Di Guglielmo, Bruno, Ramunno, Anna, Stevens, Anna Floor, Heer, Dominik, Lamponi, Stefania, Gemma, Sandra, Benz, Jörg, Di Marzo, Vincenzo, van der Stelt, Mario, Piomelli, Daniele, Campiani, Giuseppe

“…New potent, selective monoacylglycerol lipase (MAGL) inhibitors based on the azetidin-2-one scaffold ((±)-5a–v, (±)-6a–j, and (±)-7a–d) were developed as…”
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Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain by He, Yingfang, Grether, Uwe, Taddio, Marco F., Meier, Carla, Keller, Claudia, Edelmann, Martin R., Honer, Michael, Huber, Sylwia, Wittwer, Matthias B., Heer, Dominik, Richter, Hans, Collin, Ludovic, Hug, Melanie N., Hilbert, Manuel, Postmus, Annemarieke G.J., Stevens, Anna Floor, van der Stelt, Mario, Krämer, Stefanie D., Schibli, Roger, Mu, Linjing, Gobbi, Luca C.

“…Monoacylglycerol lipase (MAGL) is a gatekeeper in regulating endocannabinoid signaling and has gained substantial attention as a therapeutic target for…”
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