Search Results - "Postma, Cindy"
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Immune checkpoint inhibition-related colitis: symptoms, endoscopic features, histology and response to management
Published in ESMO open (01-01-2018)“…BackgroundImmune checkpoint inhibitors are successfully introduced as anticancer treatment. However, they may induce severe immune-related adverse events…”
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2
Oral cavity cancer in two young patients with ulcerative colitis, a case report
Published in Acta oto-laryngologica case reports (31-12-2023)“…AbstractPatients with Inflammatory Bowel Disease (IBD) are at increased risk of developing malignancies. IBD patients with oral cavity cancer may have reduced…”
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3
Genomic profiling of gastric cancer predicts lymph node status and survival
Published in Oncogene (27-03-2003)“…Gastric carcinogenesis is driven by an accumulation of genetic changes that to a large extent occur at the chromosomal level. We analysed the patterns of…”
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Genomic alterations in primary gastric adenocarcinomas correlate with clinicopathological characteristics and survival
Published in Analytical cellular pathology (Amsterdam) (2004)“…Pathogenesis of gastric cancer is driven by an accumulation of genetic changes that to a large extent occur at the chromosomal level. In order to investigate…”
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Promoter methylation precedes chromosomal alterations in colorectal cancer development
Published in Analytical cellular pathology (Amsterdam) (2006)“…Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship…”
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6
Immune checkpoint inhibition-related colitis: Correlation between ulcers and need for infliximab
Published in Journal of clinical oncology (20-05-2017)“…Abstract only e21062 Background: Immune checkpoint inhibition has improved survival of patients with several types of advanced cancer. With these new…”
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Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2002)“…Background & Aims: Current models of colorectal adenoma to carcinoma progression do not fully reflect the genetic heterogeneity and complexity of the disease…”
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Intratumor heterogeneity of k-ras and p53 mutations among human colorectal adenomas containing early cancer
Published in Analytical cellular pathology (2000)“…The molecular pathways and the timing of genetic events during human colorectal carcinogenesis are still not fully understood. We have addressed the intratumor…”
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Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression
Published in Tumor biology (01-04-2010)“…Colorectal adenomas form a biologically and clinically distinct intermediate stage in development of colorectal cancer (CRC) from normal colon epithelium. Only…”
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Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism
Published in Cellular oncology (Dordrecht) (01-02-2012)“…Background Colorectal cancer develops in a multi-step manner from normal epithelium, through a pre-malignant lesion (so-called adenoma), into a malignant…”
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Abstract 3086: Gain of chromosome 13 is a cause of CDK8 overexpression associated with colorectal adenoma to carcinoma progression
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Introduction: Colorectal adenomas are common precursors of colorectal cancer (CRC). About only 5% of adenomas progress to cancer and this progression…”
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Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations
Published in Carcinogenesis (New York) (01-02-2008)“…Colorectal cancer (CRC) is a complex and heterogeneous disease in which genomic instability and DNA promoter methylation play important roles. The aim of this…”
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LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21
Published in Oncogene (29-05-2003)“…Recently, the gene PTPRJ (protein tyrosine phosphatase receptor type J) was identified as the candidate gene for the mouse colon cancer susceptibility locus…”
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Loss of 1p36, gain of 8q24, and loss of 9q34 are associated with stroma percentage of colorectal cancer
Published in Cancer letters (18-12-2007)“…Abstract Interactions between neoplastic cells and neighboring stromal cells affect tumor morphology and behavior. The present study aimed to identify specific…”
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P52: Microarray-CGH analysis of the 8q22–q23, 13q21–q31 and 20q amplicons associated with colorectal cancer progression
Published in European journal of medical genetics (01-10-2005)Get full text
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Genomic profling of gastric cancer predicts lymph node status and survival
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2003)Get full text
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Interaction of 65- and 62-kD proteins from the apical membranes of the Aedes aegypti larvae midgut epithelium with Cry4B and Cry11A endotoxins of Bacillus thuringiensis
Published in Biochemistry (Moscow) (01-05-2002)“…A protein with the molecular weight of 65 kD is the only component of Aedes aegypti larvae BBM capable to specifically bind mosquitocidal toxins Cry4B and…”
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Small bowel adenocarcinomas are more similar to colorectal than gastric cancer according to their chromosomal copy number profile
Published in Cancer genetics and cytogenetics (01-11-2010)Get full text
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