Search Results - "Postle, A. D."

Acute respiratory distress syndrome and acute lung injury by Dushianthan, A, Grocott, M P W, Postle, A D, Cusack, R

“…Acute respiratory distress syndrome (ARDS) is a life threatening respiratory failure due to lung injury from a variety of precipitants. Pathologically ARDS is…”
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Cortisol clearance and associations with insulin sensitivity, body fat and fatty liver in middle-aged men by HOLT, H. B, WILD, S. H, BYRNE, C. D, POSTLE, A. D, ZHANG, J, KOSTER, G, UMPLEBY, M, SHOJAEE-MORADIE, F, DEWBURY, K, WOOD, P. J, PHILLIPS, D. I

“…The regulation of cortisol metabolism in vivo is not well understood. We evaluated the relationship between cortisol metabolism and insulin sensitivity,…”
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Lipidome analysis of Symbiodiniaceae reveals possible mechanisms of heat stress tolerance in reef coral symbionts by Rosset, S., Koster, G., Brandsma, J., Hunt, A. N., Postle, A. D., D’Angelo, C.

“…Climate change-induced global warming threatens the survival of key ecosystems including shallow water coral reefs. Elevated temperatures can disrupt the…”
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A robust and versatile mass spectrometry platform for comprehensive assessment of the thiol redox metabolome by Sutton, T.R., Minnion, M., Barbarino, F., Koster, G., Fernandez, B.O., Cumpstey, A.F., Wischmann, P., Madhani, M., Frenneaux, M.P., Postle, A.D., Cortese-Krott, M.M., Feelisch, M.

“…Several diseases are associated with perturbations in redox signaling and aberrant hydrogen sulfide metabolism, and numerous analytical methods exist for the…”
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Exogenous surfactant supplementation in infants with respiratory syncytial virus bronchiolitis by TIBBY, Shane M, HATHERILL, Mark, WRIGHT, Sarah M, WILSON, Peter, POSTLE, Anthony D, MURDOCH, Ian A

“…Infants with respiratory syncytial virus (RSV) bronchiolitis are deficient in surfactant, both in quantity and ability to reduce surface tension. New evidence…”
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The effect of eicosapentaenoic acid on rat lymphocyte proliferation depends upon its position in dietary triacylglycerols by Kew, S, Wells, S, Thies, F, McNeill, G P, Quinlan, P T, Clark, G T, Dombrowsky, H, Postle, A D, Calder, P C

“…Animal and human studies have shown that greatly increasing the amount of fish oil [rich in long-chain (n-3) PUFA] in the diet can decrease lymphocyte…”
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Electrospray ionisation mass spectrometric analysis of lipid restructuring in the carp (Cyprinus carpio L.) during cold acclimation by Brooks, S, Clark, G T, Wright, S M, Trueman, R J, Postle, A D, Cossins, A R, Maclean, N M

“…Cold acclimation of carp from 30 degrees C to 10 degrees C causes a restructuring of liver microsomal phospholipids characterised by increased proportions of…”
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Multi-omic analysis of the effects of low frequency ventilation during cardiopulmonary bypass surgery by Durham, A.L., Al Jaaly, E., Graham, R., Brook, P.O., Bae, J.H., Heesom, K.J., Postle, A.D., Lavender, P., Jazrawi, E., Reeves, B., Fiorentino, F., Mumby, S., Angelini, G.D., Adcock, I.M.

“…Heart surgery with cardio-pulmonary bypass (CPB) is associated with lung ischemia leading to injury and inflammation. It has been suggested this is a result of…”
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Mass spectroscopic analysis of phosphatidylinositol synthesis using 6-deuteriated-myo-inositol: comparison of the molecular specificities and acyl remodelling mechanisms in mouse tissues and cultured cells by Postle, A D, Dombrowsky, H, Clarke, H, Pynn, C J, Koster, G, Hunt, A N

“…Mammalian cell PtdIns (phosphatidylinositol) in vivo is enriched in the sn-1-stearoyl 2-arachidonoyl species, the physiological precursor of…”
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Lipidomic analysis of the molecular specificity of a cholinephosphotransferase in situ by Hunt, A N, Fenn, H C, Clark, G T, Wright, M M, Postle, A D, McMaster, C R

“…Dynamic lipidomics using ESI-MS (tandem electrospray ionization mass spectrometry) of 9-deuterated choline (choline-d(9)) incorporation into mammalian cell…”
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The role of pulmonary surfactant in the asthmatic response by Postle, A D

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Mechanisms of hepatic phosphatidylcholine synthesis in adult rat: effects of pregnancy by Burdge, G C, Hunt, A N, Postle, A D

“…Late pregnancy in the rat (gestational ages 16-21 days) was accompanied by a specific increase in hepatic phosphatidylcholine (PC) and phosphatidylethanolamine…”
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Lung surfactants and asthma by Postle, A D

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High-performance liquid chromatographic analysis of phospholipids from different sources with combined fluorescence and ultraviolet detection by Bernhard, W, Linck, M, Creutzburg, H, Postle, A D, Arning, A, Martin-Carrera, I, Sewing, K F

“…An isocratic high-performance liquid chromatographic (HPLC) system was developed for the separation of major phospholipid classes, i.e., phosphatidylcholine,…”
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Mechanisms of hepatic phosphatidylcholine synthesis in the developing guinea pig : contributions of acyl remodelling and of N-methylation of phosphatidylethanolamine by BURDGE, G. C, KELLY, F. J, POSTLE, A. D

“…Hepatic phosphatidylcholine (PC) from the immature fetal guinea pig at day 55 of gestation comprised mainly unsaturated molecular species containing C18:2(n-6)…”
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The composition of individual molecular species of plasma phosphatidylcholine in human pregnancy by Postle, Anthony D., Al, Monique D.M., Burdge, Graham C., Hornstra, Gerard

“…The molecular species composition of plasma phosphatidylcholine (PC) was measured in sequential blood samples from 13 pregnant women from 16 weeks of gestation…”
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Highly saturated endonuclear phosphatidylcholine is synthesized in situ and colocated with CDP-choline pathway enzymes by Hunt, A N, Clark, G T, Attard, G S, Postle, A D

“…Chromatin-associated phospholipids are well recognized. A report that catalytically active endonuclear CTP:choline-phosphate cytidylyltransferase alpha is…”
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Hepatic phospholipid molecular species in the guinea pig adaptations to pregnancy by Burdge, Graham C., Postle, Anthony D.

“…Incorporation of polyunsaturated fatty acids (PUFA), particularly 22∶6n−3, into fetal brain at specific gestational ages is critical for development of normal…”
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A comparison of the molecular species compositions of mammalian lung surfactant phospholipids by Postle, Anthony D, Heeley, Emma L, Wilton, David C

“…While dipalmitoyl phosphatidylcholine (PC16:0/16:0) is essential for pulmonary surfactant function, roles for other individual molecular species of surfactant…”
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Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development by McElroy, M C, Postle, A D, Kelly, F J

“…The developmental expression of catalase, superoxide dismutase (both Mn-SOD and Cu/Zn-SOD) and glutathione peroxide activities were determined in human lung…”
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