Search Results - "Pospech, Jola"

Ruthenium-Catalyzed Oxidative C–H Bond Alkenylations in Water: Expedient Synthesis of Annulated Lactones by Ackermann, Lutz, Pospech, Jola

“…Ruthenium-catalyzed cross-dehydrogenative C–H bond alkenylations occurred efficiently in environmentally benign water, which was exploited for an oxidative…”
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Alternative Metals for Homogeneous Catalyzed Hydroformylation Reactions by Pospech, Jola, Fleischer, Ivana, Franke, Robert, Buchholz, Stefan, Beller, Matthias

“…Transition‐metal‐catalyzed hydroformylation reactions constitute one of the most powerful tools for CC bond formation in organic synthesis and represent an…”
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Heteroarene N‐Oxides as Oxygen Source in Organic Reactions by Petrosyan, Andranik, Hauptmann, Richy, Pospech, Jola

“…This review summarizes the utilization of heteroarene N‐oxides as oxidant in organic reactions. The specific focus lies on reactions in which pyridine N‐oxides…”
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Photo-Mediated Decarboxylative Giese-Type Reaction Using Organic Pyrimidopteridine Photoredox Catalysts by El-Hage, Firas, Schöll, Christopher, Pospech, Jola

“…The decarboxylative Giese-type reaction offers a versatile methodology for the radical alkylation of electron-deficient alkenes. Photo-mediated variants often…”
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Synthesis of (+)-Pancratistatins via Catalytic Desymmetrization of Benzene by Hernandez, Lucas W, Pospech, Jola, Klöckner, Ulrich, Bingham, Tanner W, Sarlah, David

“…A concise synthesis of (+)-pancratistatin and (+)-7-deoxypancratistatin from benzene using an enantioselective, dearomative carboamination strategy has been…”
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Nickel-Catalyzed Dearomative trans-1,2-Carboamination by Hernandez, Lucas W, Klöckner, Ulrich, Pospech, Jola, Hauss, Lilian, Sarlah, David

“…We describe the development of an arenophile-mediated, nickel-catalyzed dearomative trans-1,2-carboamination protocol. A range of readily available aromatic…”
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Ruthenium-Catalyzed Carbonylative CC Coupling in Water by Directed CH Bond Activation by Tlili, Anis, Schranck, Johannes, Pospech, Jola, Neumann, Helfried, Beller, Matthias

“…First things first: The title reaction of arenes bearing ortho‐directing groups (DG) in the presence of a ruthenium catalyst and aryl iodide is presented. The…”
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Arenophile-Mediated Dearomative Reduction by Okumura, Mikiko, Nakamata Huynh, Stephanie M., Pospech, Jola, Sarlah, David

“…A dearomative reduction of simple arenes has been developed which employs a visible‐light‐mediated cycloaddition of arenes with an N‐N‐arenophile and in situ…”
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Mechanistic Insight into the Mode of Action of Acid β-Glucosidase Enhancer Ambroxol by Pantoom, Supansa, Hules, Larissa, Schöll, Christopher, Petrosyan, Andranik, Monticelli, Maria, Pospech, Jola, Cubellis, Maria Vittoria, Hermann, Andreas, Lukas, Jan

“…Ambroxol (ABX) is a mucolytic agent used for the treatment of respiratory diseases. Bioactivity has been demonstrated as an enhancement effect on lysosomal…”
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Regioselective Ruthenium-Catalyzed Carbonylative Direct Arylation of Five-Membered and Condensed Heterocycles by Pospech, Jola, Tlili, Anis, Spannenberg, Anke, Neumann, Helfried, Beller, Matthias

“…A ruthenium‐catalyzed carbonylative CH bond arylation process for the three‐component synthesis of complex aryl–(hetero)aryl ketones in an aqueous solution…”
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Role of endoplasmic reticulum stress and protein misfolding in disorders of the liver and pancreas by Lukas, Jan, Pospech, Jola, Oppermann, Christina, Hund, Christina, Iwanov, Katharina, Pantoom, Supansa, Petters, Janine, Frech, Moritz, Seemann, Susanne, Thiel, Franziska-Gisela, Modenbach, Jana-Marielle, Bolsmann, Robert, de Freitas Chama, Laura, Kraatz, Franziska, El-Hage, Firas, Gronbach, Manuel, Klein, Annelie, Müller, Regina, Salloch, Sabine, Weiss, Frank-Ulrich, Simon, Peter, Wagh, Preshit, Klemenz, Almuth, Krüger, Elke, Mayerle, Julia, Delcea, Mihaela, Kragl, Udo, Beller, Matthias, Rolfs, Arndt, Lerch, Markus M., Sendler, Matthias

“…The endoplasmic reticulum (ER) is the site of synthesis and folding of membrane and secretory proteins. The fraction of protein passing through the ER…”
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Ruthenium-Catalyzed Hydroaroylation of Styrenes in Water through Directed CH Bond Activation by Tlili, Anis, Schranck, Johannes, Pospech, Jola, Neumann, Helfried, Beller, Matthias

“…Selective CH bond‐functionalization reactions of arenes offer the potential for a more benign synthesis of fine chemicals and organic building blocks for the…”
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Palladium-Catalyzed Synthesis of N , N- Dimethylanilines via Buchwald-Hartwig Amination of (Hetero)aryl Triflates by Taeufer, Tobias, Pospech, Jola

“…This work delineates the synthesis of , -dimethylaniline derivatives from dimethylamines and aryl triflates. The palladium-catalyzed C-N bond formation…”
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Well-Defined Ruthenium(II) Carboxylate as Catalyst for Direct C–H/C–O Bond Arylations with Phenols in Water by Ackermann, Lutz, Pospech, Jola, Potukuchi, Harish Kumar

“…The ruthenium(II) carboxylate complex [Ru(O2CMes)2(p-cymene)] enabled efficient direct arylations of unactivated C–H bonds with easily available, inexpensive…”
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Versatile Synthesis of Isocoumarins and α-Pyrones by Ruthenium-Catalyzed Oxidative C–H/O–H Bond Cleavages by Ackermann, Lutz, Pospech, Jola, Graczyk, Karolina, Rauch, Karsten

“…An inexpensive cationic ruthenium(II) catalyst enabled the expedient synthesis of isocoumarins through oxidative annulations of alkynes by benzoic acids. This…”
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Ruthenium-Catalyzed Carbonylative CC Coupling in Water by Directed CH Bond Activation by Tlili, Anis, Schranck, Johannes, Pospech, Jola, Neumann, Helfried, Beller, Matthias

“…Auf das Wesentliche konzentriert: Die Titelreaktion kuppelt Arene mit ortho‐dirigierenden Gruppen (DG) mit verschiedenartig substituierten Aryliodiden in…”
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1-[(Methylsulfonyl)oxy]pyridin-1-ium methanesulfonate by Taeufer, Tobias, Spannenberg, Anke, Pospech, Jola

“…The title molecular salt, C 6 H 8 NO 3 S + ·CH 3 O 3 S − , consists of a cationic sulfonated pyridine N -oxide moiety and a methanesulfonate anion. An N—O bond…”
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Palladium-Catalyzed Direct Arylations, Alkenylations, and Benzylations through C−H Bond Cleavages with Sulfamates or Phosphates as Electrophiles by Ackermann, Lutz, Barfüsser, Sebastian, Pospech, Jola

“…A catalytic system comprised of Pd(OAc)2 and bidentate ligand dppe enabled first direct arylations with moisture-stable aryl sulfamates as electrophiles, and…”
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Dearomative dihydroxylation with arenophiles by Southgate, Emma H., Pospech, Jola, Fu, Junkai, Holycross, Daniel R., Sarlah, David

“…Aromatic hydrocarbons are some of the most elementary feedstock chemicals, produced annually on a million metric ton scale, and are used in the production of…”
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Photomediated Hydro- and Deuterodecarboxylation of Pharmaceutically Relevant and Natural Aliphatic Carboxylic Acids by Mayer, Thea S., Taeufer, Tobias, Brandt, Sina, Rabeah, Jabor, Pospech, Jola

“…Herein, we report a photomediated hydro- and deuterodecarboxylation of different primary, secondary, and tertiary carboxylic acids catalyzed by an organic…”
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