Search Results - "Posner, J B"

Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients by Gultekin, S. Humayun, Rosenfeld, Myrna R., Voltz, Raymond, Eichen, Joseph, Posner, Jerome B., Dalmau, Josep

“…Paraneoplastic limbic encephalitis (PLE) is a rare disorder characterized by personality changes, irritability, depression, seizures, memory loss and sometimes…”
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Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies by ROJAS, I, GRAUS, F, KEIME-GUIBERT, F, RENE, R, DELATTRE, J. Y, RAMON, J. M, DALMAU, J, POSNER, J. B

“…The outcome of 34 women with anti-Yo-associated paraneoplastic cerebellar degeneration was reviewed. Three patients had not developed cancer after more than 4…”
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Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival by Graus, F, Dalmou, J, Reñé, R, Tora, M, Malats, N, Verschuuren, J J, Cardenal, F, Viñolas, N, Garcia del Muro, J, Vadell, C, Mason, W P, Rosell, R, Posner, J B, Real, F X

“…Anti-Hu antibodies (HuAb) recognize antigens expressed by neurons and small-cell lung cancer (SCLC). High titers of HuAb were initially reported in serum from…”
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Small-cell lung cancer, paraneoplastic cerebellar degeneration and the Lambert-Eaton myasthenic syndrome by MASON, W. P, GRAUS, F, POSNER, J. B, DALMAU, J, LANG, B, HONNORAT, J, DELATTRE, J.-Y, VALLDEORIOLA, F, ANTOINE, J. C, ROSENBLUM, M. K, ROSENFELD, M. R, NEWSOM-DAVIS, J

“…Several cancers, especially lung, ovarian and breast, can cause paraneoplastic cerebellar degeneration. The presence of different antineuronal antibodies…”
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Motor neuron syndromes in cancer patients by Forsyth, P A, Dalmau, J, Graus, F, Cwik, V, Rosenblum, M K, Posner, J B

“…Previous reports indicate that motor neuron disease (MND) may rarely be associated with systemic cancer. We have encountered 14 patients with MND and cancer…”
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A Serologic Marker of Paraneoplastic Limbic and Brain-Stem Encephalitis in Patients with Testicular Cancer by Voltz, Raymond, Gultekin, S. Humayun, Rosenfeld, Myrna R, Gerstner, Elizabeth, Eichen, Joseph, Posner, Jerome B, Dalmau, Josep

“…The identification of antibodies against neuronal proteins in the serum and cerebrospinal fluid of patients with both cancer and a specific neurologic disorder…”
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Immunization with the paraneoplastic encephalomyelitis antigen HuD does not cause neurologic disease in mice by SMITT, P. A. E. S, MANLEY, G. T, POSNER, J. B

“…Paraneoplastic encephalomyelitis/paraneoplastic sensory neuronopathy (PEM/PSN) associated with small cell lung cancer is characterized by high serum and CSF…”
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Steroid myopathy in cancer patients by BATCHELOR, T. T, TAYLOR, L. P, THALER, H. T, POSNER, J. B, DEANGELIS, L. M

“…We prospectively evaluated 15 adult cancer patients being treated with adrenocorticosteroids (steroids) to determine the frequency and time course of "steroid…”
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MRI changes in intracranial hypotension by PANNULLO, S. C, REICH, J. B, KROL, G, DECK, M. D. F, POSNER, J. B

“…We report seven patients with the syndrome of intracranial hypotension who were referred to Memorial Sloan-Kettering, primarily because of suspicion of…”
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Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders by DALMAU, J, GULTEKIN, S. H, POSNER, J. B, ROSENFELD, M. R, VOLTZ, R, HOARD, R, DESCHAMPS, T, BALMACEDA, C, BATCHELOR, T, GERSTNER, E, EICHEN, J, FRENNIER, J

“…The identification of antineuronal antibodies has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated…”
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T-cell receptor analysis in anti-Hu associated paraneoplastic encephalomyelitis by VOLTZ, R, DALMAU, J, POSNER, J. B, ROSENFELD, M. R

“…To analyze the T-cell receptor (TCR) repertoire in the inflammatory infiltrates of the nervous system and tumor of patients with anti-Hu associated…”
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The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues by Dalmau, J, Furneaux, HM, Cordon-Cardo, C, Posner, JB

“…Using immunohistochemistry or Western blot analysis, the authors have studied the expression of the Hu antigen (a neuronal protein identified by the serum of…”
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DNA vaccination with HuD inhibits growth of a neuroblastoma in mice by CARPENTIER, A. F, ROSENFELD, M. R, DELATTRE, J.-Y, WHALEN, R. G, POSNER, J. B, DALMAU, J

“…Some patients with small cell lung cancer (SCLC) or neuroblastoma develop an immune response against HuD, a human homologue of the Drosophila protein, elav,…”
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Management of brain metastases by Posner, J B

“…Brain metastases are common and often occur in patients whose systemic cancer is quiescent. When brain metastases occur, they considerably decrease the quality…”
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Headaches in patients with brain tumors : a study of 111 patients by FORSYTH, P. A, POSNER, J. B

“…We examined 111 consecutive patients with primary or metastatic brain tumors identified by CT or MRI to characterize brain tumor headache. The median age was…”
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HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal by Szabo, A, Dalmau, J, Manley, G, Rosenfeld, M, Wong, E, Henson, J, Posner, J B, Furneaux, H M

“…A neuronal antigen (HuD) recognized by the sera of patients with antibody-associated paraneoplastic encephalomyelitis has been isolated by screening a lambda…”
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Paraneoplastic Syndromes Involving the Nervous System by Darnell, Robert B, Posner, Jerome B

“…Paraneoplastic neurologic syndromes are incited by a tumor outside the nervous system that produces a characteristic antigen of the nervous system. An immune…”
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Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system by Buckanovich, R J, Posner, J B, Darnell, R B

“…Paraneoplastic opsoclonus-ataxia, a disorder of motor control, develops in breast or lung cancer patients who harbor an antibody (Ri) that recognizes their…”
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Paraneoplastic cerebellar degeneration. II: Clinical and immunologic findings in 21 patients with Hodgkin's disease by HAMMACK, J, KOTANIDES, H, ROSENBLUM, M. K, POSNER, J. B

“…We reviewed clinical findings and serologic data on 18 men and three women with paraneoplastic cerebellar degeneration (PCD) associated with Hodgkin's disease…”
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Paraneoplastic syndromes affecting the nervous system by Dalmau, J O, Posner, J B

“…Paraneoplastic syndromes can affect virtually any portion of the nervous system. Most paraneoplastic syndromes are believed to be caused by an autoimmune…”
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