Search Results - "Posfai, Gyorgy"

A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species by Nyerges, Ákos, Csörgő, Bálint, Nagy, István, Bálint, Balázs, Bihari, Péter, Lázár, Viktória, Apjok, Gábor, Umenhoffer, Kinga, Bogos, Balázs, Pósfai, György, Pál, Csaba

“…Currently available tools for multiplex bacterial genome engineering are optimized for a few laboratory model strains, demand extensive prior modification of…”
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Bacterial evolution of antibiotic hypersensitivity by Lázár, Viktória, Pal Singh, Gajinder, Spohn, Réka, Nagy, István, Horváth, Balázs, Hrtyan, Mónika, Busa‐Fekete, Róbert, Bogos, Balázs, Méhi, Orsolya, Csörgő, Bálint, Pósfai, György, Fekete, Gergely, Szappanos, Balázs, Kégl, Balázs, Papp, Balázs, Pál, Csaba

“…The evolution of resistance to a single antibiotic is frequently accompanied by increased resistance to multiple other antimicrobial agents. In sharp contrast,…”
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Indispensability of Horizontally Transferred Genes and Its Impact on Bacterial Genome Streamlining by Karcagi, Ildikó, Draskovits, Gábor, Umenhoffer, Kinga, Fekete, Gergely, Kovács, Károly, Méhi, Orsolya, Balikó, Gabriella, Szappanos, Balázs, Györfy, Zsuzsanna, Fehér, Tamás, Bogos, Balázs, Blattner, Frederick R, Pál, Csaba, Pósfai, György, Papp, Balázs

“…Why are certain bacterial genomes so small and compact? The adaptive genome streamlining hypothesis posits that selection acts to reduce genome size because of…”
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Emergent Properties of Reduced-Genome Escherichia coli by Pósfai, György, Plunkett, Guy III, Fehér, Tamás, Frisch, David, Keil, Günther M, Umenhoffer, Kinga, Kolisnychenko, Vitaliy, Stahl, Buffy, Sharma, Shamik S, de Arruda, Monika, Burland, Valerie, Harcum, Sarah W, Blattner, Frederick R

“…With the use of synthetic biology, we reduced the Escherichia coli K-12 genome by making planned, precise deletions. The multiple-deletion series (MDS)…”
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System-level genome editing in microbes by Csörgő, Bálint, Nyerges, Ákos, Pósfai, György, Fehér, Tamás

“…Highlights • Innovative new technologies allow system-level, high throughput genome editing. • Recombineering offers high specificity and multiplexing ability…”
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Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs by Csörgo, Bálint, Fehér, Tamás, Tímár, Edit, Blattner, Frederick R, Pósfai, György

“…Molecular mechanisms generating genetic variation provide the basis for evolution and long-term survival of a population in a changing environment. In stable,…”
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Reduced evolvability of Escherichia coli MDS42, an IS-less cellular chassis for molecular and synthetic biology applications by Umenhoffer, Kinga, Fehér, Tamás, Balikó, Gabriella, Ayaydin, Ferhan, Pósfai, János, Blattner, Frederick R, Pósfai, György

“…Evolvability is an intrinsic feature of all living cells. However, newly emerging, evolved features can be undesirable when genetic circuits, designed and…”
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Engineered ribosomal RNA operon copy-number variants of E. coli reveal the evolutionary trade-offs shaping rRNA operon number by Gyorfy, Zsuzsanna, Draskovits, Gabor, Vernyik, Viktor, Blattner, Frederick F, Gaal, Tamas, Posfai, Gyorgy

“…Ribosomal RNA (rrn) operons, characteristically present in several copies in bacterial genomes (7 in E. coli), play a central role in cellular physiology. We…”
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Conditional DNA repair mutants enable highly precise genome engineering by Nyerges, Ákos, Csörgő, Bálint, Nagy, István, Latinovics, Dóra, Szamecz, Béla, Pósfai, György, Pál, Csaba

“…Oligonucleotide-mediated multiplex genome engineering is an important tool for bacterial genome editing. The efficient application of this technique requires…”
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Genome sequence of enterohaemorrhagic Escherichia coli O157:H7 by Perna, Nicole T, Plunkett, Guy, Burland, Valerie, Mau, Bob, Glasner, Jeremy D, Rose, Debra J, Mayhew, George F, Evans, Peter S, Gregor, Jason, Kirkpatrick, Heather A, Pósfai, György, Hackett, Jeremiah, Klink, Sara, Boutin, Adam, Shao, Ying, Miller, Leslie, Grotbeck, Erik J, Davis, N. Wayne, Lim, Alex, Dimalanta, Eileen T, Potamousis, Konstantinos D, Apodaca, Jennifer, Anantharaman, Thomas S, Lin, Jieyi, Yen, Galex, Schwartz, David C, Welch, Rodney A, Blattner, Frederick R

“…The bacterium Escherichia coli O157:H7 is a worldwide threat to public health and has been implicated in many outbreaks of haemorrhagic colitis, some of which…”
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Competition between transposable elements and mutator genes in bacteria by Fehér, Tamás, Bogos, Balázs, Méhi, Orsolya, Fekete, Gergely, Csörgo, Bálint, Kovács, Károly, Pósfai, György, Papp, Balázs, Hurst, Laurence D, Pál, Csaba

“…Although both genotypes with elevated mutation rate (mutators) and mobilization of insertion sequence (IS) elements have substantial impact on genome…”
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Versatile insertion plasmids for targeted genome manipulations in bacteria: isolation, deletion, and rescue of the pathogenicity island LEE of the Escherichia coli O157:H7 genome by Posfai, Gyorgy, Koob, Michael D, Kirkpatrick, Heather A, Blattner, Frederick R

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Markerless gene replacement in Escherichia coli stimulated by a double-strand break in the chromosome by Pósfai, György, Kolisnychenko, Vitaliy, Bereczki, Zsuzsa, Blattner, Frederick R.

“…A simple and efficient gene replacement method, based on the recombination and repair activities of the cell, was developed. The method permits the targeted…”
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In the fast lane: Large-scale bacterial genome engineering by Fehér, Tamás, Burland, Valerie, Pósfai, György

“…► We review recent results in high throughput genome engineering. ► Large scale synthesis of oligonucleotides, and assembly into genes and genomes. ► Highly…”
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Role of DNA minor groove interactions in substrate recognition by the M.SinI and M.EcoRII DNA (cytosine-5) methyltransferases by Kiss, A, Pósfai, G, Zsurka, G, Raskó, T, Venetianer, P

“…The SinI and EcoRII DNA methyltransferases recognize sequences (GG(A)/(T)CC and CC(A)/(T)GG, respectively), which are characterized by an (A)/(T) ambiguity…”
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Enhancing the Translational Capacity of E. coli by Resolving the Codon Bias by Lipinszki, Zoltan, Vernyik, Viktor, Farago, Nora, Sari, Tobias, Puskas, Laszlo G, Blattner, Frederick R, Posfai, Gyorgy, Gyorfy, Zsuzsanna

“…Escherichia coli is a well-established and popular host for heterologous expression of proteins. The preference in the choice of synonymous codons (codon…”
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Exploring the fitness benefits of genome reduction in Escherichia coli by a selection-driven approach by Vernyik, Viktor, Karcagi, Ildikó, Tímár, Edit, Nagy, István, Györkei, Ádám, Papp, Balázs, Györfy, Zsuzsanna, Pósfai, György

“…Artificial simplification of bacterial genomes is thought to have the potential to yield cells with reduced complexity, enhanced genetic stability, and…”
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The Complete Genome Sequence of Escherichia coli DH10B: Insights into the Biology of a Laboratory Workhorse by DURFEE, Tim, NELSON, Richard, GIBBS, Richard A, CSÖRGO, Balint, POSFAI, György, WEINSTOCK, George M, BLATTNER, Frederick R, BALDWIN, Schuyler, PLUNKETT, Guy, BURLAND, Valerie, MAU, Bob, PETROSINO, Joseph F, XIANG QIN, MUZNY, Donna M, AYELE, Mulu

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The dawn of evolutionary genome engineering by Pál, Csaba, Papp, Balázs, Pósfai, György

“…In this Opinion article, the authors highlight the potential of genome engineering for the study of evolution and focus on microbial systems. They discuss the…”
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erratum Genome sequence of enterohaemorrhagic Escherichia coli 0157:H7 by Perna, Nicole T, Plunkett, Guy, Burland, Valerie, Mau, Bob, Glasner, Jeremy D, Rose, Debra J, Mayhew, George F, Evans, Peter S, Gregor, Jason, Kirkpatrick, Heather A, Pósfai, György, Hackett, Jeremiah, Klink, Sara, Boutin, Adam, Shao, Ying, Miller, Leslie, Grotbeck, Erik J, Davis, N. Wayne, Lim, Alex, Dimalanta, Eileen T, Potamousis, Konstantinos D, Apodaca, Jennifer, Anantharaman, Thomas S, Lin, Jieyi, Yen, Galex, Schwartz, David C, Welch, Rodney A, Blattner, Frederick R

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