Search Results - "Poschet, Jens F"
-
1
Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity
Published in The Journal of clinical investigation (01-11-2007)“…Progressive pulmonary disease and infections with Pseudomonas aeruginosa remain an intractable problem in cystic fibrosis (CF). At the cellular level, CF is…”
Get full text
Journal Article -
2
Mycobacteria Inhibit Nitric Oxide Synthase Recruitment to Phagosomes during Macrophage Infection
Published in Infection and Immunity (01-05-2004)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
3
Nonclassical Pathway of Pseudomonas aeruginosa DNA-Induced Interleukin-8 Secretion in Cystic Fibrosis Airway Epithelial Cells
Published in Infection and Immunity (01-05-2006)“…Pseudomonas aeruginosa is a critical colonizer of the respiratory tract in cystic fibrosis. The chronic infections with this microorganism contribute to…”
Get full text
Journal Article -
4
Hyperacidification of Cellubrevin Endocytic Compartments and Defective Endosomal Recycling in Cystic Fibrosis Respiratory Epithelial Cells
Published in The Journal of biological chemistry (19-04-2002)“…The cystic fibrosis transmembrane conductance regulator (CFTR), which is aberrant in patients with cystic fibrosis, normally functions both as a chloride…”
Get full text
Journal Article -
5
Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis
Published in American journal of physiology. Lung cellular and molecular physiology (01-09-2007)“…The CFTR gene encodes a chloride channel with pleiotropic effects on cell physiology and metabolism. Here, we show that increasing cGMP levels to inhibit…”
Get more information
Journal Article -
6
Chloroquine normalizes aberrant transforming growth factor beta activity in cystic fibrosis bronchial epithelial cells
Published in Pediatric pulmonology (01-08-2006)“…Cystic fibrosis (CF) remains a fatal progressive disease in spite of the discovery and characterization of the CFTR gene. Transforming growth factor beta…”
Get full text
Journal Article -
7
Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade
Published in EMBO reports (01-05-2006)“…Endosomal hyperacidification in cystic fibrosis (CF) respiratory epithelial cells is secondary to a loss of sodium transport control owing to a defective form…”
Get full text
Journal Article -
8
Characterisation of penicillin-G uptake in rabbit small-intestinal brush-border membrane vesicles
Published in Biochimica et biophysica acta (31-01-1996)“…Uptake of penicillin-G has been studied in rabbit intestinal brush-border membrane vesicles (BBMV). Penicillin-G was transported into the lumen of BBMV via an…”
Get full text
Journal Article