Search Results - "Posadino, Anna Maria"
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Potential Adverse Effects of Resveratrol: A Literature Review
Published in International journal of molecular sciences (18-03-2020)“…Due to its health benefits, resveratrol (RE) is one of the most researched natural polyphenols. Resveratrol's health benefits were first highlighted in the…”
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Metformin-mediated epigenetic modifications in diabetes and associated conditions: Biological and clinical relevance
Published in Biochemical pharmacology (01-09-2023)“…[Display omitted] An intricate interplay between genetic and environmental factors contributes to the development of type 2 diabetes (T2D) and its…”
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Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy
Published in Colloids and surfaces, B, Biointerfaces (01-04-2017)“…Cellular transport study of RVG-9R-BACE1 siRNA complex included into uncoated (NR) and chitosan coated (C) solid lipid nanoparticles (SLN) using Caco-2 as a…”
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Iloprost Attenuates Oxidative Stress-Dependent Activation of Collagen Synthesis Induced by Sera from Scleroderma Patients in Human Pulmonary Microvascular Endothelial Cells
Published in Molecules (Basel, Switzerland) (05-08-2021)“…Endothelial cell injury is an early event in systemic sclerosis (SSc) pathogenesis and several studies indicate oxidative stress as the trigger of…”
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Citrus limon var. pompia Camarda var. nova : A Comprehensive Review of Its Botanical Characteristics, Traditional Uses, Phytochemical Profile, and Potential Health Benefits
Published in Nutrients (08-08-2024)“…, commonly known as pompia, is a distinctive citrus ecotype native to Sardinia, notable for its unique botanical, phytochemical, and potential health benefits…”
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Medicinal and mechanistic overview of artemisinin in the treatment of human diseases
Published in Biomedicine & pharmacotherapy (01-07-2023)“…Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has been traditionally used to treat conditions such as malaria, cancer,…”
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Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published in Antioxidants (02-02-2021)“…Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. Endothelial-to-mesenchymal-transition…”
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Protective Effect of Cyclically Pressurized Solid⁻Liquid Extraction Polyphenols from Cagnulari Grape Pomace on Oxidative Endothelial Cell Death
Published in Molecules (Basel, Switzerland) (21-08-2018)“…The aim of this work is the evaluation of a green extraction technology to exploit winery waste byproducts. Specifically, a solid⁻liquid extraction technology…”
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Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival
Published in Biomolecules (Basel, Switzerland) (30-05-2019)“…Dietary intake of natural antioxidants is thought to impart protection against oxidative-associated cardiovascular diseases. Despite many in vivo studies and…”
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An updated overview of cyanidins for chemoprevention and cancer therapy
Published in Biomedicine & pharmacotherapy (01-07-2023)“…Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used…”
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Potential Therapeutic Targets of Resveratrol in the Prevention and Treatment of Pulmonary Fibrosis
Published in Frontiers in bioscience (Landmark. Print) (14-09-2023)“…Pulmonary fibrosis (PF) is a feared component in over 200 interstitial pulmonary diseases, which are characterized by increased alveolar wall thickness,…”
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NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs
Published in Biomolecular Concepts (21-02-2022)“…Systemic sclerosis (SSc) is an immune disorder characterized by diffuse fibrosis and vascular abnormalities of the affected organs. Although the etiopathology…”
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Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells
Published in Toxicology in vitro (01-08-2017)“…Green tea consumption has been shown to possess cancer chemopreventive activity. Polyphenol E (PE) is a widely used standardized green tea extract formulation…”
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Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
Published in Metabolites (27-08-2022)“…The use and abuse of cannabis, be it for medicinal or recreational purposes, is widely spread among the population. Consequently, a market for more potent and…”
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Disease-Associated Regulation of Non-Coding RNAs by Resveratrol: Molecular Insights and Therapeutic Applications
Published in Frontiers in cell and developmental biology (13-07-2022)“…There have been significant advances, particularly over the last 20 years, in the identification of non-coding RNAs (ncRNAs) and their pathophysiological role…”
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Targeted Biocompatible Nanoparticles for the Delivery of (−)-Epigallocatechin 3-Gallate to Prostate Cancer Cells
Published in Journal of medicinal chemistry (10-03-2011)“…Molecular targeted cancer therapy mediated by nanoparticles (NPs) is a promising strategy to overcome the lack of specificity of conventional chemotherapeutic…”
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Protective Effect of Knee Postoperative Fluid on Oxidative-Induced Damage in Human Knee Articular Chondrocytes
Published in Antioxidants (01-02-2024)“…The oxidative-stress-elicited deterioration of chondrocyte function is the initial stage of changes leading to the disruption of cartilage homeostasis. These…”
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Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies
Published in Nanoscale research letters (28-03-2011)“…Docetaxel (Dtx) chemotherapy is the optional treatment in patients with hormone-refractory metastatic prostate cancer, and Dtx-loaded polymeric nanoparticles…”
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Evaluation of non-covalent interactions between serum albumin and green tea catechins by affinity capillary electrophoresis
Published in Journal of Chromatography A (07-11-2014)“…•The first ACE method for studying the interaction between catechins and albumin is reported.•The Kb of the 4 main green tea catechins for both Bovine and…”
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Antioxidant Properties of Olive Mill Wastewater Polyphenolic Extracts on Human Endothelial and Vascular Smooth Muscle Cells
Published in Foods (08-04-2021)“…This work aims to analyze the chemical and biological evaluation of two extracts obtained by olive mill wastewater (OMW), an olive oil processing byproduct…”
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