Search Results - "Posada, M"

Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas by Amoozgar, Zohreh, Kloepper, Jonas, Ren, Jun, Tay, Rong En, Kazer, Samuel W., Kiner, Evgeny, Krishnan, Shanmugarajan, Posada, Jessica M., Ghosh, Mitrajit, Mamessier, Emilie, Wong, Christina, Ferraro, Gino B., Batista, Ana, Wang, Nancy, Badeaux, Mark, Roberge, Sylvie, Xu, Lei, Huang, Peigen, Shalek, Alex K., Fukumura, Dai, Kim, Hye-Jung, Jain, Rakesh K.

“…Immune checkpoint blockers (ICBs) have failed in all phase III glioblastoma (GBM) trials. Here, we show that regulatory T (Treg) cells play a key role in GBM…”
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Prevalence of Autism Spectrum Disorder in a large Italian catchment area: a school-based population study within the ASDEU project by Narzisi, A, Posada, M, Barbieri, F, Chericoni, N, Ciuffolini, D, Pinzino, M, Romano, R, Scattoni, M L, Tancredi, R, Calderoni, S, Muratori, F

“…This study aims to estimate Autism Spectrum Disorders (ASD) prevalence in school-aged children in the province of Pisa (Italy) using the strategy of the ASD in…”
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Physiologically‐Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug–Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations by Taskar, Kunal S., Pilla Reddy, Venkatesh, Burt, Howard, Posada, Maria M., Varma, Manthena, Zheng, Ming, Ullah, Mohammed, Emami Riedmaier, Arian, Umehara, Ken‐ichi, Snoeys, Jan, Nakakariya, Masanori, Chu, Xiaoyan, Beneton, Maud, Chen, Yuan, Huth, Felix, Narayanan, Rangaraj, Mukherjee, Dwaipayan, Dixit, Vaishali, Sugiyama, Yuichi, Neuhoff, Sibylle

“…Physiologically‐based pharmacokinetic (PBPK) modeling has been extensively used to quantitatively translate in vitro data and evaluate temporal effects from…”
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A novel perovskite oxide chemically designed to show multiferroic phase boundary with room-temperature magnetoelectricity by Fernández-Posada, Carmen M., Castro, Alicia, Kiat, Jean-Michel, Porcher, Florence, Peña, Octavio, Algueró, Miguel, Amorín, Harvey

“…There is a growing activity in the search of novel single-phase multiferroics that could finally provide distinctive magnetoelectric responses at room…”
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Wood density is related to aboveground biomass and productivity along a successional gradient in upper Andean tropical forests by Castillo-Figueroa, Dennis, González-Melo, Andrés, Posada, Juan M.

“…Wood density (WD) is a key functional trait related to ecological strategies and ecosystem carbon dynamics. Despite its importance, there is a considerable…”
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Predicting Clinical Effects of CYP3A4 Modulators on Abemaciclib and Active Metabolites Exposure Using Physiologically Based Pharmacokinetic Modeling by Posada, Maria M., Morse, Bridget L., Turner, P. Kellie, Kulanthaivel, Palaniappan, Hall, Stephen D., Dickinson, Gemma L.

“…Abemaciclib, a selective inhibitor of cyclin‐dependent kinases 4 and 6, is metabolized mainly by cytochrome P450 (CYP)3A4. Clinical studies were performed to…”
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Diverging functional strategies but high sensitivity to an extreme drought in tropical dry forests by González‐M., Roy, Posada, Juan M., Carmona, Carlos P., Garzón, Fabián, Salinas, Viviana, Idárraga‐Piedrahita, Álvaro, Pizano, Camila, Avella, Andrés, López‐Camacho, René, Norden, Natalia, Nieto, Jhon, Medina, Sandra P., Rodríguez‐M., Gina M., Franke‐Ante, Rebeca, Torres, Alba M., Jurado, Rubén, Cuadros, Hermes, Castaño‐Naranjo, Alejandro, García, Hernando, Salgado‐Negret, Beatriz, Archibald, Sally

“…Extreme drought events have negative effects on forest diversity and functioning. At the species level, however, these effects are still unclear, as species…”
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Mechanistic understanding of the phase behavior of supersaturated solutions of poorly water-soluble drugs by Tres, Francesco, Posada, Maria M., Hall, Stephen D., Mohutsky, Michael A., Taylor, Lynne S.

“…[Display omitted] Amorphous solid dispersions (ASDs) are a promising formulation strategy to increase both the apparent aqueous solubility and bioavailability…”
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Informal housing, spatial structure, and city compactness by Posada, Héctor M.

“…This paper develops a monocentric city model with a formal and an informal sector in the housing industry. While formal developers build houses renting land…”
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Prediction of the Renal Organic Anion Transporter 1 (OAT1)- Mediated Drug Interactions for LY404039, the Active Metabolite of Pomaglumetad Methionil by Pak, Y. Anne, Posada, Maria M., Bacon, James, Long, Amanda, Annes, William, Witcher, Jennifer, Mitchell, Malcolm, Tirona, Rommel G., Hall, Stephen D., Hillgren, Kathleen M.

“…Purpose The objective of this work was to demonstrate that clinical OAT1-mediated DDIs can be predicted using physiologically based pharmacokinetic (PBPK)…”
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Taking advantage of solving the resource constrained multi-project scheduling problems using multi-modal genetic algorithms by Pérez, E., Posada, M., Lorenzana, A.

“…In this paper, for the first time, multi-modal genetic algorithms (MMGAs) are proposed to optimize the resource constrained multi-project scheduling problem…”
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The Polar/Antipolar Phase Boundary of BiMnO3–BiFeO3–PbTiO3: Interplay among Crystal Structure, Point Defects, and Multiferroism by Fernández‐Posada, Carmen M., Castro, Alicia, Kiat, Jean‐Michel, Porcher, Florence, Peña, Octavio, Jiménez, Ricardo, Algueró, Miguel, Amorín, Harvey

“…The ferromagnetic perovskite oxide BiMnO3 is a highly topical material, and the solid solutions it forms with antiferromagnetic/ferroelectric BiFeO3 and with…”
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Do Disciplinary Sanctions Affect Political Parties’ Re-election? Evidence from Colombia by Posada, Héctor M., Burbano Valencia, Enrique Javier, Mondragón-Mayo, Angie

“…Our study examines whether citizens punish political misbehavior by estimating the impact of disciplinary sanctions on the re-election of political parties in…”
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ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold by Posada, Itziar M D, Serulla, Marc, Zhou, Yong, Oetken-Lindholm, Christina, Abankwa, Daniel, Lectez, Benoît

“…Ras-induced senescence mediated through ASPP2 represents a barrier to tumour formation. It is initiated by ASPP2's interaction with Ras at the plasma membrane,…”
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Immunocytochemical evaluation of aquaporins and cell wall components and their influence on foliar water uptake in Andean Melastomataceae by Boanares, D., Posada‐Herrera, J. M., Bragança, G. P. P., Arriola, I. A., Caldeira, C. F., Costa, L. E. N., Gastauer, M., França, M. G. C., Isaias, R. M. d. S.

“…Andean ecosystems are characterized by high humidity, mainly from rain and fog events. Because of differences in altitude two Andean ecosystems – sub‐Andean…”
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Role of magnetic ordering in the phase coexistence at the structural instability of the multiferroic BiFeO3–PbTiO3 by Fernández-Posada, Carmen M., Castro, Alicia, del Real, Rafael P., Algueró, Miguel, Amorín, Harvey

“…A promising approach for obtaining a large magnetoelectric response at room temperature in single-phase materials is to make use of phase-change phenomena at…”
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Relevance of PepT1 in the Intestinal Permeability and Oral Absorption of Cefadroxil by Posada, Maria M., Smith, David E.

“…ABSTRACT Purpose To determine the contribution of intestinal PepT1 on the permeability and oral absorption of the β-lactam antibiotic drug cefadroxil. Methods…”
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The effect of commuting costs and transport subsidies on informality rates by Moreno-Monroy, Ana I., Posada, Héctor M.

“…In this article we study the relationship between accessibility and informality using a spatial search model. In the model, formal workers commute every day to…”
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Prediction of renal transporter mediated drug-drug interactions for pemetrexed using physiologically based pharmacokinetic modeling by Posada, Maria M, Bacon, James A, Schneck, Karen B, Tirona, Rommel G, Kim, Richard B, Higgins, J William, Pak, Y Anne, Hall, Stephen D, Hillgren, Kathleen M

“…Pemetrexed, an anionic anticancer drug with a narrow therapeutic index, is eliminated mainly by active renal tubular secretion. The in vitro to in vivo…”
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Toxicity of cobalt-chromium nanoparticles released from a resurfacing hip implant and cobalt ions on primary human lymphocytes in vitro by Posada, Olga M., Tate, R. J., Grant, M. H.

“…Adverse tissue responses to prostheses wear particles and released ions are important contributors to hip implant failure. In implant‐related adverse reactions…”
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