Search Results - "Posada, James"
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Assessment of the Impact of RNase in Patients With Severe Fatigue Related to Post-Acute Sequelae of SARS-CoV-2 Infection: A Randomized Phase 2 Trial of RSLV-132
Published in Clinical infectious diseases (26-09-2024)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and RNA debris persist in viral reservoirs for weeks to months following infection,…”
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Evaluation of RNase therapy in systemic lupus erythematosus: a randomised phase 2a clinical trial of RSLV-132
Published in Lupus science & medicine (07-02-2024)“…BackgroundCirculating, extracellular RNA is the primary trigger of type I interferon in systemic lupus erythematosus (SLE), and interferon is known to play a…”
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Blood-Borne RNA Correlates with Disease Activity and IFN-Stimulated Gene Expression in Systemic Lupus Erythematosus
Published in The Journal of immunology (1950) (01-10-2016)“…The loss of tolerance and the presence of circulating autoantibodies directed against nuclear Ags is the hallmark of systemic lupus erythematosus (SLE). Many…”
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Inhibition of T Cell Antigen Receptor Signaling by VHR-related MKPX (VHX), a New Dual Specificity Phosphatase Related to VH1 Related (VHR)
Published in The Journal of biological chemistry (15-02-2002)“…A cDNA encoding a novel, human, dual-specific protein phosphatase was identified in the Incyte data base. The open reading frame predicted a protein of 184…”
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Starch and chitosan oligosaccharides as interpenetrating phases in poly(N-isopropylacrylamide) injectable gels
Published in Materials Science & Engineering C (01-04-2014)“…Thermosensitive interpenetrating gels were prepared by physically blending poly(N-isopropylacrylamide) (PNIPA) as the matrix and the following polysaccharides…”
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Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2021)Get full text
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Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2021)Get full text
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Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2021)Get full text
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Improvement of Severe Fatigue Following Nuclease Therapy in Patients With Primary Sjögren’s Syndrome: A Randomized Clinical Trial
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-01-2021)“…Objective To assess the safety and efficacy of RSLV‐132, an RNase Fc fusion protein, in a phase II randomized, double‐blind, placebo‐controlled clinical trial…”
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Activation of Multiple Mitogen-activated Protein Kinase Signal Transduction Pathways by the Endothelin B Receptor Requires the Cytoplasmic Tail
Published in The Journal of biological chemistry (06-12-1996)“…Endothelin is a 21-amino acid peptide with remarkably diverse biological properties, including potent vasoconstriction, induction of mitogenesis, and a role in…”
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Transmembrane Helix 7 of the Endothelin B Receptor Regulates Downstream Signaling
Published in The Journal of biological chemistry (09-04-1999)“…Endothelin is a 21-amino acid peptide with a striking diversity of important biological responses, including, vasoconstriction, bronchoconstriction, and…”
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12
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Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2021)Get full text
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Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2021)Get full text
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Generación de Actividades Novedosas para el Aprendizaje y la Enseñanza del Inglés: Un Enfoque de Estilos de Aprendizaje
Published 01-01-2021“…En vista de que el estilo de aprendizaje de cada estudiante es diferente, las actividades que se utilizan en el aula de lengua extranjera (en adelante LE)…”
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Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor
Published in Cancer research (Chicago, Ill.) (01-12-1996)“…Asbestos fibers are human carcinogens with undefined mechanisms of action. In studies here, we examined signal transduction events induced by asbestos in…”
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Requirements for Phosphorylation of MAP Kinase During Meiosis in Xenopus Oocytes
Published in Science (American Association for the Advancement of Science) (10-01-1992)“…Mitogen-activated protein (MAP) kinases are activated in response to a variety of extracellular stimuli by phosphorylation on tyrosine and threonine residues…”
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Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro
Published in Molecular and Cellular Biology (01-04-1993)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle cell proliferation
Published in American journal of respiratory cell and molecular biology (01-05-1997)“…Endothelin is a small peptide that is a potent bronchoconstrictor, mitogen for airway smooth muscle (ASM), and is believed to be involved in the pathogenesis…”
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JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells
Published in European journal of immunology (01-05-1996)“…Fas is a cell surface molecule that is expressed on a wide array of cell types and triggers apoptosis. While in most situations Fas ligation activates…”
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The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase and c-Jun NH2-terminal Kinase Groups of Mitogen-activated Protein Kinases (∗)
Published in The Journal of biological chemistry (08-03-1996)“…In airway smooth muscle cells ligand binding to the seven-transmembrane endothelin and thrombin receptors stimulates cell growth. Rapid activation of the…”
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