Search Results - "Porvari, K."

Expression profiling of PC-3 cell line variants and comparison of MIC-1 transcript levels in benign and malignant prostate by Patrikainen, L., Porvari, K., Kurkela, R., Hirvikoski, P., Soini, Y., Vihko, P.

“…Background  The mechanisms behind prostate cancer progression are largely unknown, but macrophage inhibitory cytokine 1 (MIC‐1) has been suggested to be…”
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Expression profiling of PC-3 cell line variants and comparison of MIC-I transcript levels in benign and malignant prostate by PATRIKAINEN, L, PORVARI, K, KURKELA, R, HIRVIKOSKI, P, SOINI, Y, VIHKO, P

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Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues by Vaarala, Markku H., Porvari, Katja S., Kellokumpu, Sakari, Kyllönen, Atte P., Vihko, Pirkko T.

“…The purpose of this study was to clarify the expression of TMPRSS2 in mice during development and to compare the tissue distribution of the transcripts in…”
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17β-Hydroxysteroid dehydrogenases and cancers by Vihko, P., Härkönen, P., Oduwole, O., Törn, S., Kurkela, R., Porvari, K., Pulkka, A., Isomaa, V.

“…17β-Hydroxysteroid dehydrogenases (17HSDs) catalyze the interconversions between active 17β-hydroxysteroids and less-active 17-ketosteroids thereby affecting…”
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127P The mutational landscape, oncogenic pathways and mutational signatures of breast neuroendocrine tumors by Karihtala, P., Porvari, K., Roininen, N., Voutilainen, S., Mattson, J., Heikkilä, P., Haapasaari, K-M., Selander, K.

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PB0869 Platelet-Derived Microvesicles Have a Reparative Role for Muscle Damage Induced by Hypothermia by Horioka, K., Tanaka, H., Hayakawa, A., Pakanen, L., Porvari, K.

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Several genes encoding ribosomal proteins are over‐expressed in prostate‐cancer cell lines: Confirmation of L7a and L37 over‐expression in prostate‐cancer tissue samples by Vaarala, Markku H., Porvari, Katja S., Kyllönen, Atte P., Mustonen, Mika V. J., Lukkarinen, Olavi, Vihko, Pirkko T.

“…A cDNA library specific for mRNA over‐expressed in prostate cancer was generated by subtractive hybridization of transcripts originating from prostatic…”
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P3823The role of genetics in apparently acquired non-ischemic cardiomyopathies leading to sudden cardiac death by Holmstrom, L, Pylkas, K, Mantere, T, Porvari, K, Pakanen, L, Kortelainen, M L, Kerkela, R, Huikuri, H, Junttila, M J

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Comparison of human prostate specific glandular kallikrein 2 and prostate specific antigen gene expression in prostate with gene amplification and overexpression of prostate specific glandular kallikrein 2 in tumor tissue by Herrala, Annakaisa M., Porvari, Katja S., Kyllönen, Atte P., Vihko, Pirkko T.

“…BACKGROUND There is a need for specific markers that can indicate the different stages of prostate carcinoma. There is ongoing speculation concerning the value…”
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Bioprotective role of platelet-derived microvesicles in hypothermia: Insight into the differential characteristics of peripheral and splenic platelets by Horioka, Kie, Tanaka, Hiroki, Okaba, Keisuke, Yamada, Shinnosuke, Hayakawa, Akira, Ishii, Namiko, Motomura, Ayumi, Inoue, Hiroyuki, Takauji, Shuhei, Isozaki, Shotaro, Ogawa, Katsuhiro, Yajima, Daisuke, Druid, Henrik, Pakanen, Lasse, Porvari, Katja

“…Most platelets are present in peripheral blood, but some are stored in the spleen. Because the tissue environments of peripheral blood vessels and the spleen…”
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1211Genetic background of sudden cardiac death caused by idiopathic myocardial fibrosis by Holmstrom, L., Pylkas, K., Mantere, T., Porvari, K., Kortelainen, M.L., Pakanen, L., Kerkela, R., Huikuri, H., Junttila, J.

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P481The genetic background of sudden cardiac deaths caused by single vessel coronary artery disease and myocardial hypertrophy with fibrosis by Vahatalo, J H, Holmstrom, L T A, Pylkas, K, Porvari, K, Pakanen, L, Kaikkonen, K S, Perkiomaki, J S, Huikuri, H V, Junttila, M J

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Site-directed mutagenesis of prostatic acid phosphatase. Catalytically important aspartic acid 258, substrate specificity, and oligomerization by Porvari, K S, Herrala, A M, Kurkela, R M, Taavitsainen, P A, Lindqvist, Y, Schneider, G, Vihko, P T

“…At the active site of rat prostatic acid phosphatase (rPAP), residue Asp258 is a suitable candidate to act as an acid/base catalyst during phosphoester…”
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Differential Androgen Regulation of Rat Prostatic Acid Phosphatase Transcripts by Porvari, K., Kurkela, R., Kivinen, A., Vihko, P.

“…Steady-state levels of the mRNAs encoding rat prostatic acid phosphatase (rPAP) were measured from the ventral prostate of rats after castration and…”
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Rat acid phosphatase: overexpression of active, secreted enzyme by recombinant baculovirus-infected insect cells, molecular properties, and crystallization by Vihko, P. (University of Oulu, Oulu, Finland), Kurkela, R, Porvari, K, Herrala, A, Lindfors, A, Lindqvist, Y, Schneider, G

“…Rat prostatic acid phosphatase (rPAP; orthophosphoric-monoester phosphohydrolase (acid optimum), EC (3.1.3.2) was expressed in the baculovirus expression…”
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Structural comparison of human and rat prostate-specific acid phosphatase genes and their promoters: identification of putative androgen response elements by Virkkunen, P, Hedberg, P, Palvimo, J J, Birr, E, Porvari, K, Ruokonen, M, Taavitsainen, P, Jänne, O A, Vihko, P

“…Structural comparison of human and rat prostate-specific acid phosphatase (hPAP and rPAP) genes indicate that the exon number is different between these…”
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The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: Detection of mutated TMPRSS2 form in a case of aggressive disease by Vaarala, Markku H., Porvari, Katja, Kyllönen, Atte, Lukkarinen, Olavi, Vihko, Pirkko

“…The serine protease TMPRSS2 gene expression was studied by in situ hybridization using benign prostatic hyperplasia and prostate cancer tissue samples from 32…”
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Differentially Expressed Genes in Two LNCaP Prostate Cancer Cell Lines Reflecting Changes during Prostate Cancer Progression by VAARALA, M. H, PORVARI, K, KYLLÖNEN, A, VIHKO, P

“…Prostate cancer tends to become transformed to androgen-independent disease over time when treated by androgen-deprivation therapy. We used two variants of the…”
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Sex Hormone Metabolism in Prostate Cancer Cells during Transition to an Androgen-Independent State by Härkönen, Päivi, Törn, Svea, Kurkela, Riitta, Porvari, Katja, Pulkka, Anitta, Lindfors, Aija, Isomaa, Veli, Vihko, Pirkko

“…The progression of prostate cancer during androgen deprivation therapy is a serious clinical problem. Little is known, however, about the mechanisms behind the…”
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Body temperatures during three long-distance polar swims in water of 0–3 °C by Noakes, T.D., Dugas, J.P., Dugas, L.R., Tucker, R., Oksa, J., Dunn, J., van der Merwe, B.S., Dirker, J.A., Porvari, K., Smolander, J.

“…1. We report body temperature responses in a single individual to 3 swims of 1000 m or longer in ice-cold water (0–3 °C) during which he swam the normal crawl…”
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