Search Results - "Poruba, M."

The Effect of Homogeneous and Non-Homogeneous Dissolution of Meropenem on the Quality of Parenteral Treatment by Poruba, M, Štrbová, P, Urbánek, K

“…Background Parenteral administration is the main route of drug administration in intensive care unit patients. To maintain high level of treatment efficacy and…”
Get full text

Acute medication poisoning causing hospital admissions in childhood: a 3-year prospective observational single-center study by Matalová, P, Poruba, M, Wawruch, M, Ondra, P, Urbánek, K

“…Although the risks of medication poisoning in children are often reported, there is a lack of studies addressing this issue. The majority of papers deal with a…”
Get full text

The effect of combined diet containing n-3 polyunsaturated fatty acids and silymarin on metabolic syndrome in rats by Poruba, M, Anzenbacher, P, Racova, Z, Oliyarnyk, O, Hüttl, M, Malinska, H, Markova, I, Gurska, S, Kazdova, L, Vecera, R

“…The risk of development of metabolic syndrome can be increased by hypertriglyceridemia. A search for effective therapy is a subject of considerable attention…”
Get full text

Positive effects of different drug forms of silybin in the treatment of metabolic syndrome by Poruba, M, Matušková, Z, Kazdová, L, Oliyarnyk, O, Malínská, H, Tozzi di Angelo, I, Večeřa, R

“…Silymarin and silybin are widely used for their hepatoprotective properties. Our previous studies confirm positive effect of silymarin on lipoprotein profile…”
Get full text

Micronized silymarin extract reduced hepatotoxic effect of fenofibrate in hereditary hypertriglyceridemic rats by Oliyarnyk, O., Markova, I., Malinska, H., Trnovska, J., Hüttl, M., Skop, V., Matuskova, Z., Poruba, M., Vecera, R., Kazdova, L.

Get full text

The combination of atorvastatin with silymarin enhances hypolipidemic, antioxidant and anti-inflammatory effects in a rat model of metabolic syndrome by Marková, I, Malínská, H, Hüttl, M, Miklánková, D, Oliyarnyk, O, Poruba, M, Rácová, Z, Kazdová, L, Večeřa, R

“…Hypolipidemic and cardioprotective effects of statins can be associated with the development of myopathies and new-onset type 2 diabetes. These adverse effects…”
Get full text

In vitro and in silico studies of interaction of synthetic 2,6,9-trisubstituted purine kinase inhibitors BPA-302, BP-21 and BP-117 with liver drug-metabolizing cytochromes P450 by Špičáková, A, Kraus, P, Gucký, T, Kryštof, V, Strnad, M, Bazgier, V, Otyepka, M, Kubíčková, V, Poruba, M, Rácová, Z, Zapletalová, I, Anzenbacher, P

“…An evaluation of possible interactions with enzymes of drug metabolism (cytochromes P450, CYP) is an important part of studies on safety and, in general, on…”
Get full text