Search Results - "Portoles, Antonio"

Optimisation by Taguchi’s method of the electrical parameters and geometry of an S32205 duplex weld by Chacón-Fernández, Sandra, Meseguer-Valdenebro, José L., García, Antonio Portolés

“…Duplex alloys have excellent mechanical properties, as well as resistance to corrosion, but when they are welded, they present a segregation process of the…”
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Influence of welding parameters on grain size, HAZ and degree of dilution of 6063-T5 alloy: optimization through the Taguchi method of the GMAW process by Meseguer-Valdenebro, José L., Martínez-Conesa, Eusebio, Portoles, Antonio

“…The aim of this work is to design experiments using Taguchi’s method that determine the influence of welding parameters on the grain size, heat-affected zone…”
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Analysis of the Influence of GMAW Process Parameters on the Properties and Microstructure of S32001 Steel by Chacón-Fernández, Sandra, Antonio Portolés García, Labanda, Gerardo Romaní

“…The properties of duplex steels can be seriously affected when welding processes are performed on them. Duplex S32001 is a recent development, so there is very…”
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Amantadine and/or transcranial magnetic stimulation for fatigue associated with multiple sclerosis (FETEM): study protocol for a phase 3 randomised, double-blind, cross-over, controlled clinical trial by Matias-Guiu, Jordi A, González-Rosa, Javier, Hernández, Miguel Ángel, Martínez-Ginés, Maria Luisa, Portolés, Antonio, Pérez-Macías, Natalia, Benito-León, Julián, Padrón, Iván, Prieto, Julio, Matias-Guiu, Jorge

“…IntroductionFatigue is one of the most disabling symptoms of multiple sclerosis (MS), and effective treatments are lacking. Amantadine is one of the most used…”
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Economic impact of immunoglobulin replacement therapy in secondary immunodeficiency to hematological cancer: a single center observational study by Guerola, Luciana Del Campo, Sacristán, Ana Andrea García, Portolés, Antonio, Jasso, Maricruz, Guerra-Galán, Teresa, de la Fuente-Munoz, Eduardo, Palacios-Ortega, María, Fernández-Arquero, Miguel, Cuesta-Mínguez, Cristina, Rodríguez-Sanz, Aránzazu, Peña-Cortijo, Ascensión, Polo, Marta, Morales, Marta Mateo, Anguita-Mandly, Eduardo, Benítez Jiménez, Teresa, Benavente Cuesta, Celina, Sánchez-Ramón, Silvia

“…This is the first report of the health economic benefits derived from preventing infections through Immunoglobulin Replacement Therapy (IgRT) in patients with…”
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Influence of post-weld heat treatments on the formation of the sigma phase and the corrosion resistance of S32001 steel by Chacón-Fernández, Sandra, Martín, Andrea Peña, García, Antonio Portolés

“…Due to their good resistance to corrosion, duplex stainless steels are often used in more demanding environments. S32001 duplex stainless steels are of recent…”
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Academia and industry agreement on a feasibility tool for first‐time‐in‐human clinical trial units by Moraga, Paloma, Prieto, Paula, Conradie, Almari, Benhayoun, Majda, Rousell, Vicki, Davy, Maria, Fuhr, Uwe, Antonijoan Arbos, Rosa, Abad‐Santos, Francisco, Portolés, Antonio, Van Duinen, Jolanda, Carcas, Antonio J., Borobia, Alberto M.

“…First‐time‐in‐human (FTIH) trials are designed to generate information on the safety, tolerability, as well as the pharmacokinetic and pharmacodynamics profile…”
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2-year outcomes of MitraClip as a bridge to heart transplantation: The international MitraBridge registry by Munafò, Andrea Raffaele, Scotti, Andrea, Estévez-Loureiro, Rodrigo, Adamo, Marianna, Hernàndez, Antonio Portolés, Peregrina, Estefanìa Fernàndez, Gutierrez, Lola, Taramasso, Maurizio, Fam, Neil P., Ho, Edwin C., Asgar, Anita, Vitrella, Giancarlo, Raineri, Claudia, Chizzola, Giuliano, Pezzola, Elisa, Le Ruz, Robin, Montalto, Claudio, Oreglia, Jacopo A., Fraccaro, Chiara, Giannini, Cristina, Fiorelli, Francesca, Rubbio, Antonio Popolo, Ooms, J.F., Compagnone, Miriam, Marcelli, Chiara, Maffeo, Diego, Bettari, Luca, Fürholz, Monika, Arzamendi, Dabit, Guerin, Patrice, Tamburino, Corrado, Petronio, A. Sonia, Grasso, Carmelo, Agricola, Eustachio, Van Mieghem, Nicolas M., Tarantini, Giuseppe, Praz, Fabien, Pascual, Isaac, Potena, Luciano, Colombo, Antonio, Maisano, Francesco, Metra, Marco, Margonato, Alberto, Crimi, Gabriele, Saia, Francesco, Godino, Cosmo

“…In the first report from the MitraBridge registry, MitraClip as a bridge to heart transplantation (HTx) proved to be at 1-year an effective treatment strategy…”
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Single and Multiple Dose PK-PD Characterization for Carisoprodol. Part I: Pharmacokinetics, Metabolites, and 2C19 Phenotype Influence. Double-Blind, Placebo-Controlled Clinical Trial in Healthy Volunteers by Calvo, Aitana, Alonso, Saioa, Prieto, Esther, Ascaso-Del-Rio, Ana, Ortuño, Jordi, Fernandez, Nieves, Portolés, Antonio

“…Carisoprodol was authorised in 1959 without a full pharmacokinetic-pharmacodynamic (PK-PD) characterisation. We designed a crossover, double-blind,…”
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Carisoprodol Single and Multiple Dose PK-PD. Part II: Pharmacodynamics Evaluation Method for Central Muscle Relaxants. Double-Blind Placebo-Controlled Clinical Trial in Healthy Volunteers by Calvo, Aitana, González-Hidalgo, Mercedes, Terleira, Ana, Fernández, Nieves, Portolés, Antonio

“…Centrally acting skeletal muscle relaxants (CMR) such as carisoprodol are used to treat acute, painful musculoskeletal conditions, though its precise mode of…”
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Rational Design, Structure–Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants by Eichhorn, Stephanie, Hörschläger, Angelika, Steiner, Markus, Laimer, Josef, Jensen, Bettina M, Versteeg, Serge A, Pablos, Isabel, Briza, Peter, Jongejan, Laurian, Rigby, Neil, Asturias, Juan A, Portolés, Antonio, Fernandez‐Rivas, Montserrat, Papadopoulos, Nikolaos G, Mari, Adriano, Poulsen, Lars K, Lackner, Peter, Ree, Ronald, Ferreira, Fatima, Gadermaier, Gabriele

“…Scope Allergies to lipid transfer proteins involve severe adverse reactions; thus, effective and sustainable therapies are desired. Previous attempts…”
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Effect of enantiomerism on the bioequivalence of a new ibuprofen 600‐mg tablet formulation obtained by roller compaction by Matji, Antonio, Vargas, Emilio, Carvajal, Luis, Terleira, Ana Isabel, Portolés, Antonio, Garcia‐Arieta, Alfredo, Torrado, Juan J., Serrano, Dolores R.

“…The bioequivalence of a new ibuprofen 600‐mg film‐coated tablet obtained by roller compaction was studied in a crossover study with 22 healthy volunteers…”
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Chiral bioanalytical methods in bioequivalence studies of intravenous vs. oral formulations of ibuprofen by González‐Rojano, Esperanza, Marcotegui, Julio, Laredo, Leonor, Gwaza, Luther, Gordon, John, Portolés, Antonio, Vargas, Emilio, Morales‐Alcelay, Susana, García‐Arieta, Alfredo

“…According to the Ibuprofen Product‐Specific Bioequivalence Guidance of the European Medicines Agency, achiral bioanalytical methods are considered acceptable…”
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Effect of Obesity and Roux-En-Y Gastric Surgery on Omeprazole Pharmacokinetics by Portolés-Pérez, Antonio, Paterna, Ana Belén Rivas, Sánchez Pernaute, Andrés, Torres García, Antonio José, Moreno Lopera, Carmen, Chicharro, Luis M., Bandrés, Fernando, López-Picado, Amanda, Rubio, Miguel A., Castrillón, Emilio Vargas

“…Abstract Introduction: The prevalence of obesity is increasing globally. The principal aim was to evaluate whether gastric bypass surgery modifies the…”
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Effect of Roux-en-Y gastric surgery on ciprofloxacin pharmacokinetics: an obvious effect? by Rivas, Ana Belén, Lopez-Picado, Amanda, Salas-Butrón, María del Rosario, Terleira, Ana, Sanchez Pernaute, Andres, Torres Garcia, Antonio José, Moreno Lopera, Carmen, Chicharro, Luis Miguel, Bandrés, Fernando, Rubio Herrera, Miguel Angel, Portolés, Antonio, Vargas, Emilio

“…Purpose To evaluate pharmacokinetic parameters of ciprofloxacin in patients undergoing Roux-en-Y gastric surgery (RYGS). Methods Controlled, single-dose,…”
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Immune response and reactogenicity after immunization with two-doses of an experimental COVID-19 vaccine (CVnCOV) followed by a third-fourth shot with a standard mRNA vaccine (BNT162b2): RescueVacs multicenter cohort study by Ascaso-del-Rio, Ana, García-Pérez, Javier, Pérez-Olmeda, Mayte, Arana-Arri, Eunate, Vergara, Itziar, Pérez-Ingidua, Carla, Bermejo, Mercedes, Castillo de la Osa, María, Imaz-Ayo, Natale, Riaño Fernández, Ioana, Astasio González, Oliver, Díez-Fuertes, Francisco, Meijide, Susana, Arrizabalaga, Julio, Hernández Gutiérrez, Lourdes, de la Torre-Tarazona, Humberto Erick, Mariano Lázaro, Alberto, Vargas-Castrillón, Emilio, Alcamí, José, Portolés, Antonio

“…There is no evidence to date on immunogenic response among individuals who participated in clinical trials of COVID-19 experimental vaccines redirected to…”
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Response Letter to Malafarina and Colleagues by Laredo, Leonor, Vargas, Emilio, Moreno, Alfonso, Portolés, Antonio

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Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study by García-Pérez, Javier, González-Pérez, María, Castillo de la Osa, María, Borobia, Alberto M., Castaño, Luis, Bertrán, María Jesús, Campins, Magdalena, Portolés, Antonio, Lora, David, Bermejo, Mercedes, Conde, Patricia, Hernández-Gutierrez, Lourdes, Carcas, Antonio, Arana-Arri, Eunate, Tortajada, Marta, Fuentes, Inmaculada, Ascaso, Ana, García-Morales, María Teresa, Erick de la Torre-Tarazona, Humberto, Arribas, José-Ramón, Imaz-Ayo, Natale, Mellado-Pau, Eugènia, Agustí, Antonia, Pérez-Ingidua, Carla, Gómez de la Cámara, Agustín, Ochando, Jordi, Belda-Iniesta, Cristobal, Frías, Jesús, Alcamí, José, Pérez-Olmeda, Mayte

“…The CombiVacS study was designed to assess immunogenicity and reactogenicity of the heterologous ChAdOx1-S/BNT162b2 combination, and 14-day results showed a…”
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Risk of Cerebrovascular Accident Associated with Use of Antipsychotics: Population-Based Case-Control Study by Laredo, Leonor, Vargas, Emilio, Blasco, Antonio Javier, Aguilar, Maria Dolores, Moreno, Alfonso, Portolés, Antonio

“…OBJECTIVES: To explore the association between use of antipsychotics and risk of cerebrovascular accident (CVA) in individuals with dementia aged 65 and older…”
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Experimental Research on the Electrical Parameters of GMAW on Different Positions Welds by Romaní, Gerardo, Meseguer-Valdenebro, José L., Portolés, Antonio

“…This paper presents the influence of the main parameters of the GMAW welding process on ingot iron sized 300 × 125 × 3 mm 3 , with a 1 mm separation between…”
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