Search Results - "Portois, M C"
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Comparative activity of pulsed or continuous estradiol exposure on gene expression and proliferation of normal and tumoral human breast cells
Published in Journal of molecular endocrinology (01-06-2002)“…Intranasal administration of hormone replacement therapy presents an original plasma kinetic profile with transient estrogen levels giving rise to the concept…”
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Hormonal regulation of the androgen receptor expression in human prostatic cells in culture
Published in The Journal of steroid biochemistry and molecular biology (01-09-1998)“…The regulation of the androgen receptor (AR) expression was studied using immunocytochemical and Western blot techniques on separate cultures of epithelial…”
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Predominant expression of 5α-reductase type 1 in pubic skin from normal subjects and hirsute patients
Published in The journal of clinical endocrinology and metabolism (01-05-1996)“…Dihydrotestosterone (DHT), the 5 alpha-reduced metabolite of testosterone, is the active molecule triggering androgen action, and 5 alpha-reductase (5…”
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Pharmacological and molecular evidence for the expression of the two steroid 5α-reductase isozymes in normal and hyperplastic human prostatic cells in culture
Published in The Prostate (01-08-1997)“…BACKGROUND Whereas the embryological development of the human prostate is clearly dependent on steroid 5α‐reductase (5α‐R) type 2 expression, the respective…”
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Androgen insensitivity in oligospermic men: a reappraisal
Published in The journal of clinical endocrinology and metabolism (01-11-1986)“…Androgen insensitivity has been reported to be present in as many as 40% of patients with severe oligospermia. In order to evaluate further the role of…”
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6
Photoaffinity labeling of the androgen receptor from human skin fibroblasts
Published in Molecular and cellular endocrinology (01-12-1987)“…The reproducible photolabeling of the androgen receptor from human skin fibroblasts, using [3H]methyltrienolone (R-1881) as ligand is described. Crude nuclei…”
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Isoelectric focusing and 2D electrophoresis of the human androgen receptor
Published in The Journal of steroid biochemistry and molecular biology (01-01-1992)“…Nuclear androgen receptors from cultured genital skin fibroblasts were analyzed by non-denaturing isoelectric focusing (IEF) in ultrathin polyacrylamide gels…”
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Androgen dependence of the Dunning R3327G cell line in monolayer culture
Published in The Prostate (1987)“…For optimal application of new treatment strategies for prostate cancer, the basic biologic effects of androgens on cell kinetics and DNA synthesis require…”
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9
A point mutation in the second zinc finger of the DNA-binding domain of the androgen receptor gene causes complete androgen insensitivity in two siblings with receptor-positive androgen resistance
Published in Molecular endocrinology (Baltimore, Md.) (01-07-1993)“…We have analyzed the nucleotide sequence of complementary and genomic DNAs of the human androgen receptor (AR) gene in two siblings (patients 9006 and 9030)…”
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10
Plasma concentrations of ethynyl oestradiol and norethindrone after oral administration to women
Published in Journal of reproduction & fertility (01-03-1977)“…Plasma concentrations of ethynyl oestradiol and norethindrone in women were measured by radioimmunoassays after oral administration of 50 microng and 1000…”
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Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid
Published in British journal of dermatology (1951) (01-11-1988)“…The effects of zinc sulphate and azelaic acid on 5 alpha-reductase activity in human skin were studied using an in vitro assay with 1,2[3H]-testosterone as…”
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Human prostatic cells in culture: Different testosterone metabolic profile in epithelial cells and fibroblasts from normal or hyperplastic prostates
Published in The Journal of steroid biochemistry and molecular biology (01-05-1996)“…The prostate gland depends on androgens for its development and the maintainance of its differentiated structures and secretory function. We have characterized…”
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13
Receptor and biological response to estriol in the fetal uterus of guinea pig
Published in Journal of receptor research (1980)“…The binding of 3H-estriol was examined in the fetal uterus of guinea pig. The physico-chemical characteristics of the binding of 3H-estriol to macromolecules…”
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Expression of androgen receptor gene in normal subjects and patients with complete androgen insensitivity
Published in Annales d'endocrinologie (1991)“…The Androgen Receptor (AR) mRNA was studied in cultured cells from normal subjects and 10 patients with Complete (CAI, 9 patients, 5: R-, 4: R+) or Partial…”
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Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients
Published in The journal of clinical endocrinology and metabolism (01-05-1996)Get full text
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17
Radioimmunoassay of norethindrone (17 alpha-ethynyl-17 beta-hydroxy-4-estren-3-one) and ethynyl-estradiol (17 alpha-ethynyl-1,3,5, (10)-estratien-3, 17 beta-diol). Application to human plasma determination of norethindrone after oral administration of this steroid
Published in Reproduccion (01-07-1975)“…The experiment conditions for the evaluation of Norethindrone (17 alpha-Ethynyl-17 beta-hydroxy-4-estren-3-one, NET) and Ethynyl-estradiol (17 alpha-ethynyl-1,…”
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