Search Results - "Porto, Luis Cristóvão"

Characterisation of the Novel HLA‐DRB116:79 Allele Using Short‐ and Long‐Read Sequencing Technologies by Andrade, Gabriela, Cunha, Mayara, Vianna, Romulo, Porto, Luís Cristóvão, Secco, Danielle

“…ABSTRACT The novel HLA‐DRB1*16:79 allele, first described in an individual from Brazil…”
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Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries by Bezerra, Frank Silva, Lanzetti, Manuella, Nesi, Renata Tiscoski, Nagato, Akinori Cardozo, Silva, Cyntia Pecli E, Kennedy-Feitosa, Emanuel, Melo, Adriana Correa, Cattani-Cavalieri, Isabella, Porto, Luís Cristóvão, Valenca, Samuel Santos

“…Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung injury can affect several components of the respiratory system,…”
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The distribution of HLA haplotypes in the ethnic groups that make up the Brazilian Bone Marrow Volunteer Donor Registry (REDOME) by Halagan, Michael, Oliveira, Danielli Cristina, Maiers, Martin, Fabreti-Oliveira, Raquel A., Moraes, Maria Elisa Hue, Visentainer, Jeane Eliete Laguila, Pereira, Noemi Farah, Romero, Matilde, Cardoso, Juliana Fernandes, Porto, Luís Cristóvão

“…The Registries of Bone Marrow Donors around the world include more than 30 million volunteer donors from 57 different countries, and were responsible for over…”
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Putative role of HLA polymorphism among a Brazilian HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) population by Schor, Doris, Porto, Luís Cristóvão, Roma, Eric Henrique, Castro-Alves, Julio, Villela, Anna Paula, Araújo, Abelardo Q. C., Glória Bonecini-Almeida, Maria

“…Around ten million people are infected with HTLV-1 worldwide, and 1–4% develop HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP),…”
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High levels of pro-inflammatory SARS-CoV-2-specific biomarkers revealed by in vitro whole blood cytokine release assay (CRA) in recovered and long-COVID-19 patients by Gomes, Shayane Martins Rodrigues, Brito, Andréia Carolinne de Souza, Manfro, Wânia Ferraz Pereira, Ribeiro-Alves, Marcelo, Ribeiro, Roberto Stefan de Almeida, da Cal, Mariana Soares, Lisboa, Vinicius da Cunha, Abreu, Daniel Paiva Barros de, Castilho, Leda Dos Reis, Porto, Luís Cristóvão de Moares Sobrino, Mafort, Thiago Thomáz, Lopes, Agnaldo José, da Silva, Silvia Amaral Gonçalves, Dutra, Patrícia Maria Lourenço, Rodrigues, Luciana Silva

“…Cytokines induced by SARS-CoV-2 infection play a crucial role in the pathophysiology of COVID-19 and hyperinflammatory responses have been associated with poor…”
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Genomic surveillance of SARS-CoV-2 tracks early interstate transmission of P.1 lineage and diversification within P.2 clade in Brazil by Lamarca, Alessandra P, de Almeida, Luiz G. P, Francisco, Ronaldo da Silva, Lima, Lucymara Fassarella Agnez, Scortecci, Kátia Castanho, Perez, Vinícius Pietta, Brustolini, Otavio J, Sousa, Eduardo Sérgio Soares, Secco, Danielle Angst, Santos, Angela Maria Guimarães, Albuquerque, George Rego, Mariano, Ana Paula Melo, Maciel, Bianca Mendes, Gerber, Alexandra L, Guimarães, Ana Paula de C, Nascimento, Paulo Ricardo, Neto, Francisco Paulo Freire, Gadelha, Sandra Rocha, Porto, Luís Cristóvão, Campana, Eloiza Helena, Jeronimo, Selma Maria Bezerra, Vasconcelos, Ana Tereza R

“…The sharp increase of COVID-19 cases in late 2020 has made Brazil the new epicenter of the ongoing SARS-CoV-2 pandemic. The novel viral lineages P.1 (Variant…”
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Metabolic Adaptations Correlated with Antibody Response after Immunization with Inactivated SARS-CoV‑2 in Brazilian Subjects by de Souza Nogueira, Jeane, Santos-Rebouças, Cíntia Barros, Piergiorge, Rafael Mina, Valente, Ana Paula, Gama-Almeida, Marcos C., El-Bacha, Tatiana, Lopes Moreira, Maria Luiza, Baptista Marques, Bruna Silva, de Siqueira, Jessica Rodrigues, de Carvalho, Erika Martins, da Costa Ferreira, Orlando, Porto, Luís Cristóvão, Kelly da Silva Fidalgo, Tatiana, Costa dos Santos, Gilson

“…The adsorbed vaccine SARS-CoV-2 (inactivated) produced by Sinovac (SV) was the first vaccine against COVID-19 to be used in Brazil. To understand the metabolic…”
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Immune response stability to the SARS-CoV-2 mRNA vaccine booster is influenced by differential splicing of HLA genes by Santos-Rebouças, Cíntia Barros, Ferreira, Cristina dos Santos, Nogueira, Jeane de Souza, Brustolini, Otávio José, de Almeida, Luiz Gonzaga Paula, Gerber, Alexandra Lehmkuhl, Guimarães, Ana Paula de Campos, Piergiorge, Rafael Mina, Struchiner, Cláudio José, Porto, Luís Cristóvão, de Vasconcelos, Ana Tereza Ribeiro

“…Many molecular mechanisms that lead to the host antibody response to COVID-19 vaccines remain largely unknown. In this study, we used serum antibody detection…”
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Evaluation of HNF1B, KLK3, ELAC2, TMPRSS2-ERG, and CTNNB1 polymorphisms associated with prostate cancer in samples of patients from HUPE-UERJ by Menezes, Raphaela Dos Santos, Dornas, Maria Cristina, Campos, Carlos Frederico Ferreira, Rodeiro, Daniela Bouzas, Carrerette, Fabricio Borges, Oliveira, Romulo Vianna, de Souza, Brenda Amaral, Alves de Souza Carvalho, Gabriele, Brito, Ingrid Alexandre de Abreu, Silva, Dayse Aparecida, Damião, Ronaldo, Porto, Luís Cristóvão

“…Prostate cancer (PCa) is the leading cause of death among men in 48 countries. Genetic alterations play a significant role in PCa carcinogenesis. For the…”
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The effect of BCG vaccination on infection and antibody levels against SARS-CoV-2—The results of ProBCG: a multicenter randomized clinical trial in Brazil by Santos, Ana Paula, Werneck, Guilherme Loureiro, Dalvi, Ana Paula Razal, dos Santos, Carla Conceição, Tierno, Paulo Fernando Guimarães Morando Marzocchi, Condelo, Hanna Silva, Macedo, Bruna, de Medeiros Leung, Janaina Aparecida, de Souza Nogueira, Jeane, Malvão, Ludmila, Galliez, Rafael, Aguiar, Roberta, Stefan, Roberto, Knackfuss, Sabrina Modena, da Silva, Elisangela Costa, Castineiras, Terezinha Marta Pereira Pinto, de Andrade Medronho, Roberto, e Silva, José Roberto Lapa, Alves, Rogério Lopes Rufino, de Moraes Sobrino Porto, Luís Cristóvão, Rodrigues, Luciana Silva, Kritski, Afrânio Lineu, de Queiroz Mello, Fernanda Carvalho

“…•Bacillus Calmette-Guérin (BCG) could be effective against SARS-CoV-2 based on the concept of trained immunity.•COVID-19 vaccines and BCG can enhance the…”
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COPD Patients Exhibit Distinct Gene Expression, Accelerated Cellular Aging, and Bias to M2 Macrophages by da Silva, Camila Oliveira, de Souza Nogueira, Jeane, do Nascimento, Adriana Paulino, Victoni, Tatiana, Bártholo, Thiago Prudente, da Costa, Cláudia Henrique, Costa, Andrea Monte Alto, Valença, Samuel Dos Santos, Schmidt, Martina, Porto, Luís Cristóvão

“…COPD, one of world's leading contributors to morbidity and mortality, is characterized by airflow limitation and heterogeneous clinical features. Three main…”
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Use of eculizumab in a systemic lupus erythemathosus patient presenting thrombotic microangiopathy and heterozygous deletion in CFHR1-CFHR3. A case report and systematic review by de Holanda, Maria Izabel, Pôrto, Luis Cristóvão, Wagner, Teresa, Christiani, Luis Fernando, Palma, Lilian M. P.

“…The association of thrombotic microangiopathy (TMA) with systemic lupus erythematosus (SLE) has been described in 0.5 to 10% of cases, and patients present…”
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Evaluation of intracellular and extracellular trehalose as a cryoprotectant of stem cells obtained from umbilical cord blood by Motta, Juliana Pessanha Rodrigues, Paraguassú-Braga, Flávio Henrique, Bouzas, Luis Fernando, Porto, Luís Cristóvão

“…Cord blood is a source of hematopoietic stem cells used in transplantation in which hematopoietic reconstitution is necessary. This transplant modality…”
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Soluble Flt‐1, Placental Growth Factor, and Vascular Endothelial Growth Factor Serum Levels to Differentiate Between Active Lupus Nephritis During Pregnancy and Preeclampsia by Jesús, Guilherme R., Lacerda, Marcela I., Rodrigues, Bruna C., Santos, Flávia C., Nascimento, Adriana P., Cristóvão Porto, Luís, Jesús, Nilson R., Levy, Roger A., Klumb, Evandro M.

“…Objective To evaluate mean serum levels of vascular endothelial growth factor (VEGF), placental growth factor (PlGF), and soluble Flt‐1 (sFlt‐1) in pregnant…”
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Prevalence of autoimmune diseases in an admixed population of patients with type 1 diabetes: a multicenter study in Brazil by Gomes, Marilia Brito, Braga, Fernanda Oliveira, Drummond, Karla Guerra, Pinheiro, André, Leal, Franz, Porto, Luís Cristóvão, Ferreira, Livia Leite, Pinheiro, Geraldo da Rocha Castelar, Negrato, Carlos Antonio

“…The primary aim of this study was to evaluate the prevalence of autoimmune diseases (AIDs) and its associated factors in an admixed Brazilian population of…”
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Roflumilast N-oxide prevents cytokine secretion induced by cigarette smoke combined with LPS through JAK/STAT and ERK1/2 inhibition in airway epithelial cells by Victoni, Tatiana, Gleonnec, Florence, Lanzetti, Manuella, Tenor, Hermann, Valença, Samuel, Porto, Luis Cristovão, Lagente, Vincent, Boichot, Elisabeth

“…Cigarette smoke is a major cause of chronic obstructive pulmonary disease (COPD). Airway epithelial cells and macrophages are the first defense cells against…”
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HLA haplotypes and differential regional mortality caused by COVID-19 in Brazil: an ecological study based on a large bone marrow donor bank dataset by BOQUETT, JULIANO ANDRÉ, VIANNA, FERNANDA S.L., FAGUNDES, NELSON J.R., SCHROEDER, LUCAS, BARBIAN, MARCIA, ZAGONEL-OLIVEIRA, MARCELO, ANDREIS, TIAGO F., PÔRTO, LUIS CRISTÓVÃO M.S., CHIES, JOSÉ ARTUR B., SCHULER-FACCINI, LAVINIA, ASHTON-PROLLA, PATRICIA, ROSSET, CLÉVIA

“…Abstract The coronavirus disease 2019 (COVID-19) mortality rates varied among the states of Brazil during the course of the pandemics. The human leukocyte…”
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Genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in Type 1 Diabetes from an admixed Brazilian population by Azulay, Rossana Santiago de Sousa, Porto, Luís Cristóvão, Silva, Dayse Aparecida, Tavares, Maria da Glória, Reis, Roberta Maria Duailibe Ferreira, Nascimento, Gilvan Cortês, Damianse, Sabrina da Silva Pereira, Rocha, Viviane Chaves de Carvalho, Magalhães, Marcelo, Rodrigues, Vandilson, Carvalho, Paulo Ricardo Vilas Boas, Faria, Manuel dos Santos, Gomes, Marília Brito

“…This study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with…”
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How Ancestry Influences the Chances of Finding Unrelated Donors: An Investigation in Admixed Brazilians by Nunes, Kelly, Aguiar, Vitor R C, Silva, Márcio, Sena, Alexandre C, de Oliveira, Danielli C M, Dinardo, Carla L, Kehdy, Fernanda S G, Tarazona-Santos, Eduardo, Rocha, Vanderson G, Carneiro-Proietti, Anna Barbara F, Loureiro, Paula, Flor-Park, Miriam V, Maximo, Claudia, Kelly, Shannon, Custer, Brian, Weir, Bruce S, Sabino, Ester C, Porto, Luís Cristóvão, Meyer, Diogo

“…A match of HLA loci between patients and donors is critical for successful hematopoietic stem cell transplantation. However, the extreme polymorphism of HLA…”
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Analysis of Post-Sample Collection EDTA Effects on Mean Platelet Volume Values in Relation to Overweight and Obese Patient Status by Pinto, Renata V L, Rodrigues, Genilson, Simões, Rafael L, Porto, Luís Cristóvão

“…Mean platelet volume (MPV) may be a useful biomarker for platelet activation in obese patients. However, storage duration and use of anticoagulant…”
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