Search Results - "Portnoy, Alison"

Challenges of antibacterial discovery revisited by Gwynn, Michael N., Portnoy, Alison, Rittenhouse, Stephen F., Payne, David J.

“…The discovery of novel antibiotic classes has not kept pace with the growing threat of bacterial resistance. Antibiotic candidates that act at new targets or…”
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Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma by Portnoy, Alison, Kumar, Sanjay, Behm, David J, Mahar, Kelly M, Noble, Robert B, Throup, John P, Russ, Steven F

“…Urotensin II (U-II) is highly expressed in the human lung and has been implicated in regulating respiratory physiology in preclinical studies. Our objective…”
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A phase IIa study of afuresertib, an oral pan‐AKT inhibitor, in patients with Langerhans cell histiocytosis by Arceci, Robert J., Allen, Carl E., Dunkel, Ira J., Jacobsen, Eric, Whitlock, James, Vassallo, Robert, Morris, Shannon R., Portnoy, Alison, Reedy, Beth Ann, Smith, Deborah A., Noble, Robert, Murnane, Amy, Cornfeld, Mark, Rodriguez‐Galindo, Carlos, Heaney, Mark L., McClain, Kenneth, Vaiselbuh, Sarah

“…Background Langerhans cell histiocytosis (LCH) is a clonal neoplasm characterized by widely varied clinical presentations, including multisystem involvement…”
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Evaluation Of Afuresertib, An Oral Pan-AKT Inhibitor, In Patients With Langerhans Cell Histiocytosis by Arceci, Robert J., Allen, Carl E., Dunkel, Ira, Jacobsen, Eric D., Whitlock, James, Vassallo, Robert, Borrello, Ivan M., Oliff, Allen, Morris, Shannon R., Ann M Reedy, Beth, Portnoy, Alison, Smith, Deborah A., Noble, Bob, Murnane, Amy A., Szabo, Stephen A., Rodriguez-Galindo, Carlos, Heaney, Mark L., McClain, Kenneth L., Vaseilbuh, Sarah

“…▪ Langerhans cell histiocytosis (LCH) is a heterogeneous disease whose myriad manifestations result from accumulation of Langerhans cells in a variety of…”
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No let up in the search for novel antibiotics by Payne, David J, Portnoy, Alison, Pottage, John, Hong, Zhi

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Always Obtain a Rectal Temperature to Detect Febrile Illness by Portnoy, Alison

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