Search Results - "Portillo, Federico"

Sp1-regulated expression of p11 contributes to motor neuron degeneration by membrane insertion of TASK1 by García-Morales, Victoria, Rodríguez-Bey, Guillermo, Gómez-Pérez, Laura, Domínguez-Vías, Germán, González-Forero, David, Portillo, Federico, Campos-Caro, Antonio, Gento-Caro, Ángela, Issaoui, Noura, Soler, Rosa M., Garcera, Ana, Moreno-López, Bernardo

“…Disruption in membrane excitability contributes to malfunction and differential vulnerability of specific neuronal subpopulations in a number of neurological…”
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Backbone Cyclic Peptidomimetic Melanocortin-4 Receptor Agonist as a Novel Orally Administrated Drug Lead for Treating Obesity by Hess, Shmuel, Linde, Yaniv, Ovadia, Oded, Safrai, Eli, Shalev, Deborah E, Swed, Avi, Halbfinger, Efrat, Lapidot, Tair, Winkler, Ilan, Gabinet, Yael, Faier, Avi, Yarden, Dana, Xiang, Zhimin, Portillo, Federico P, Haskell-Luevano, Carrie, Gilon, Chaim, Hoffman, Amnon

“…The tetrapeptide sequence His-Phe-Arg-Trp, derived from melanocyte-stimulating hormone (αMSH) and its analogs, causes a decrease in food intake and elevates…”
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Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage Motoneuron Excitability by García-Morales, Victoria, Gento-Caro, Ángela, Portillo, Federico, Montero, Fernando, González-Forero, David, Moreno-López, Bernardo

“…Intrinsic membrane excitability (IME) sets up neuronal responsiveness to synaptic drive. Several neurotransmitters and neuromodulators, acting through…”
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Structure-activity relationship and metabolic stability studies of backbone cyclization and N-methylation of melanocortin peptides by Linde, Yaniv, Ovadia, Oded, Safrai, Eli, Xiang, Zhimin, Portillo, Federico P., Shalev, Deborah E., Haskell-Luevano, Carrie, Hoffman, Amnon, Gilon, Chaim

“…Backbone cyclization (BC) and N‐methylation have been shown to enhance the activity and/or selectivity of biologically active peptides and improve metabolic…”
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Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 Modified at the Para Position of the Benzyl Side Chain (DPhe): Importance for Mouse Melanocortin-3 Receptor Agonist versus Antagonist Activity by Proneth, Bettina, Pogozheva, Irina D, Portillo, Federico P, Mosberg, Henry I, Haskell-Luevano, Carrie

“…The melanocortin-3 and -4 receptors (MC3R, MC4R) have been implicated in energy homeostasis and obesity. Whereas the physiological role of the MC4R is…”
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Nitric Oxide-Directed Synaptic Remodeling in the Adult Mammal CNS by Sunico, Carmen R, Portillo, Federico, Gonzalez-Forero, David, Moreno-Lopez, Bernardo

“…In adult mammals, learning, memory, and restoration of sensorimotor lost functions imply synaptic reorganization that requires diffusible messengers-mediated…”
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Comparison of 6 handheld ultrasound devices by point-of-care ultrasound experts: a cross-sectional study by Perez-Sanchez, Ariadna, Johnson, Gordon, Pucks, Neysan, Soni, Riya N., Lund, Terry J. S., Andrade, Anthony J., Le, Minh-Phuong T., Solis-McCarthy, Jessica, Wong, Tanping, Ashraf, Arsal, Kumar, Andre D., Banauch, Gisela I., Verner, James R., Sodhi, Amik, Thomas, Meghan K., LoPresti, Charles, Schmitz, Hannah, Koratala, Abhilash, Hunninghake, John, Manninen, Erik, Candotti, Carolina, Minami, Taro, Mathews, Benji K., Bandak, Ghassan, Sauthoff, Harald, Mayo-Malasky, Henry, Cho, Joel, Villalobos, Nick, Proud, Kevin C., Boesch, Brandon, Fenton Portillo, Federico, Reierson, Kreegan, Malik, Manpreet, Abbas, Firas, Johnson, Tim, Haro, Elizabeth K., Mader, Michael J., Mayo, Paul, Franco-Sadud, Ricardo, Soni, Nilam J.

“…Background Point-of-care ultrasound (POCUS) has emerged as an essential bedside tool for clinicians, but lack of access to ultrasound equipment has been a top…”
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A combination of ligand SAR and receptor site-directed mutagenesis reveals requirements for antagonist activity at the melanocortin-3 receptor by Proneth, Bettina, Portillo, Federico P, Haskell-Luevano, Carrie

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Nerve injury reduces responses of hypoglossal motoneurones to baseline and chemoreceptor-modulated inspiratory drive in the adult rat by González‐Forero, David, Portillo, Federico, Sunico, Carmen R., Moreno‐López, Bernardo

“…The effects of peripheral nerve lesions on the membrane and synaptic properties of motoneurones have been extensively studied. However, minimal information…”
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A study of $^{35}$Cl excited states via $^{32}$S($\alpha, p$) by Setoodehnia, Kiana, Kelley, John H, Marshall, Caleb, Chaves, Federico Portillo, Longland, Richard

“…Presolar grains originating in oxygen-neon novae may be identified by their sulfur isotopic ratios compared with theoretical estimates. These ratios depend on…”
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Nitric oxide controls excitatory/inhibitory balance in the hypoglossal nucleus during early postnatal development by Portillo, Federico, Moreno-López, Bernardo

“…Synaptic remodeling during early postnatal development lies behind neuronal networks refinement and nervous system maturation. In particular, the respiratory…”
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The Focal-Plane Detector Package on the TUNL Split-Pole Spectrograph by Marshall, Caleb, Setoodehnia, Kiana, Kowal, Katie, Portillo, Federico, Champagne, Arthur E., Hale, Stephen, Dummer, Andrew, Longland, Richard

“…A focal-plane detector for the Enge split-pole spectrograph at the Triangle Universities Nuclear Laboratory has been designed. The detector package consists of…”
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Targeting autotaxin impacts disease advance in the SOD1‐G93A mouse model of amyotrophic lateral sclerosis by Gento‐Caro, Ángela, Vilches‐Herrando, Esther, Portillo, Federico, González‐Forero, David, Moreno‐López, Bernardo

“…A preclinical strategy to broaden the search of potentially effective treatments in amyotrophic lateral sclerosis (ALS) relies on identifying factors…”
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Interfering with lysophosphatidic acid receptor edg2/lpa 1 signalling slows down disease progression in SOD1-G93A transgenic mice by Gento-Caro, Ángela, Vilches-Herrando, Esther, García-Morales, Victoria, Portillo, Federico, Rodríguez-Bey, Guillermo, González-Forero, David, Moreno-López, Bernardo

“…Alterations in excitability represent an early hallmark in Amyotrophic Lateral Sclerosis (ALS). Therefore, deciphering the factors that impact motor neuron…”
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The Focal-Plane Detector Package on the TUNL Split-Pole Spectrograph by Marshall, Caleb, Setoodehnia, Kiana, Kowal, Katie, Portillo, Federico, Champagne, Arthur E., Hale, Stephen, Dummer, Andrew, Longland, Richard

“…A focal plane detector for the Enge Split-pole Spectrograph at Triangle Universities Nuclear Laboratory has been designed. The detector package consists of two…”
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Interfering with lysophosphatidic acid receptor edg2/lpa1 signalling slows down disease progression in SOD1‐G93A transgenic mice by Gento‐Caro, Ángela, Vilches‐Herrando, Esther, García‐Morales, Victoria, Portillo, Federico, Rodríguez‐Bey, Guillermo, González‐Forero, David, Moreno‐López, Bernardo

“…Aims Alterations in excitability represent an early hallmark in Amyotrophic Lateral Sclerosis (ALS). Therefore, deciphering the factors that impact motor…”
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Role of tau protein on neocortical and hippocampal oscillatory patterns by Cantero, Jose L., Moreno-Lopez, Bernardo, Portillo, Federico, Rubio, Alicia, Hita-Yañez, Eva, Avila, Jesus

“…Tau is a neuronal microtubule‐associated protein implicated in microtubules stabilization, axonal establishment and elongation during neuronal morphogenesis…”
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High Resolution Study of 40Ca to Constrain Potassium Nucleosynthesis in NGC 2419 by Fox, William, Longland, Richard, Marshall, Caleb, Portillo-Chaves, Federico

“…The globular cluster NGC 2419 was the first to exhibit a Mg-K anticorrelation, linked to hydrogen burning at temperatures between 80-260 MK. However, the key…”
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Tau protein role in sleep-wake cycle by Cantero, Jose L, Hita-Yañez, Eva, Moreno-Lopez, Bernardo, Portillo, Federico, Rubio, Alicia, Avila, Jesus

“…Evidence has shown that the lack of tau produces subtle changes in neuronal structure and modest impairment in complex behaviors, suggesting compensatory…”
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Inhibition of Resting Potassium Conductances by Long-Term Activation of the NO/cGMP/Protein Kinase G Pathway: A New Mechanism Regulating Neuronal Excitability by Gonzalez-Forero, David, Portillo, Federico, Gomez, Laura, Montero, Fernando, Kasparov, Sergey, Moreno-Lopez, Bernardo

“…Glutamate-induced excitotoxicity, the most common pathological mechanism leading to neuronal death, may occur even with normal levels of glutamate if it…”
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