Search Results - "Porter, Craig T."

abYsis: Integrated Antibody Sequence and Structure—Management, Analysis, and Prediction by Swindells, Mark B., Porter, Craig T., Couch, Matthew, Hurst, Jacob, Abhinandan, K.R., Nielsen, Jens H., Macindoe, Gary, Hetherington, James, Martin, Andrew C.R.

“…abYsis is a web-based antibody research system that includes an integrated database of antibody sequence and structure data. The system can be interrogated in…”
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Effective Function Annotation through Catalytic Residue Conservation by George, Richard A., Spriggs, Ruth V., Bartlett, Gail J., Gutteridge, Alex, MacArthur, Malcolm W., Porter, Craig T., Al-Lazikani, Bissan, Thornton, Janet M., Swindells, Mark B.

“…Because of the extreme impact of genome sequencing projects, protein sequences without accompanying experimental data now dominate public databases. Homology…”
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The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data by Porter, Craig T., Bartlett, Gail J., Thornton, Janet M.

“…The Catalytic Site Atlas (CSA) provides catalytic residue annotation for enzymes in the Protein Data Bank. It is available online at…”
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BiopLib and BiopTools--a C programming library and toolset for manipulating protein structure by Porter, Craig T, Martin, Andrew C R

“…We describe BiopLib, a mature C programming library for manipulating protein structure, and BiopTools, a set of command-line tools which exploit BiopLib. The…”
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Analysis of Catalytic Residues in Enzyme Active Sites by Bartlett, Gail J., Porter, Craig T., Borkakoti, Neera, Thornton, Janet M.

“…We present an analysis of the residues directly involved in catalysis in 178 enzyme active sites. Specific criteria were derived to define a catalytic residue,…”
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Using a Library of Structural Templates to Recognise Catalytic Sites and Explore their Evolution in Homologous Families by Torrance, James W., Bartlett, Gail J., Porter, Craig T., Thornton, Janet M.

“…Catalytic site structure is normally highly conserved between distantly related enzymes. As a consequence, templates representing catalytic sites have the…”
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SAAPdb web resource: A large-scale structural analysis of mutant proteins by Hurst, Jacob M, McMillan, Lisa E.M, Porter, Craig T, Allen, James, Fakorede, Adebola, Martin, Andrew C.R

“…The Single Amino Acid Polymorphism database (SAAPdb) is a new resource for the analysis and visualization of the structural effects of mutations. Our…”
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The (βα)8 glycosidases: sequence and structure analyses suggest distant evolutionary relationships by Nagano, Nozomi, Porter, Craig T., Thornton, Janet M.

“…There are currently at least nine distinct glycosidase sequence families which are all known to adopt a TIM barrel fold [Henrissat,B. and Davies,G. (1997)…”
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A template search reveals mechanistic similarities and differences in β-ketoacyl synthases (KAS) and related enzymes by Dawe, Jennifer H., Porter, Craig T., Thornton, Janet M., Tabor, Alethea B.

“…A detailed comparison of the active sites in β‐ketoacyl synthases (KAS) and related enzymes has been made. Using three‐dimensional templates of the three…”
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