Search Results - "Portela Catani, João Paulo"

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells by Ma, Yuting, Adjemian, Sandy, Mattarollo, Stephen R., Yamazaki, Takahiro, Aymeric, Laetitia, Yang, Heng, Portela Catani, João Paulo, Hannani, Dalil, Duret, Helene, Steegh, Kim, Martins, Isabelle, Schlemmer, Frederic, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Menger, Laurie, Vacchelli, Erika, Droin, Nathalie, Galluzzi, Lorenzo, Krzysiek, Roman, Gordon, Siamon, Taylor, Philip R., Van Endert, Peter, Solary, Eric, Smyth, Mark J., Zitvogel, Laurence, Kroemer, Guido

“…The therapeutic efficacy of anthracyclines relies on antitumor immune responses elicited by dying cancer cells. How chemotherapy-induced cell death leads to…”
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Anti-neuraminidase and anti-hemagglutinin immune serum can confer inter-lineage cross protection against recent influenza B by Portela Catani, João Paulo, Ysenbaert, Tine, Smet, Anouk, Vuylsteke, Marnik, Vogel, Thorsten U, Saelens, Xavier

“…Influenza B viruses (IBV) are responsible for a considerable part of the burden caused by influenza virus infections. Since their emergence in the 1980s, the…”
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The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017 by Catani, João Paulo Portela, Smet, Anouk, Ysenbaert, Tine, Vuylsteke, Marnik, Bottu, Guy, Mathys, Janick, Botzki, Alexander, Cortes-Garcia, Guadalupe, Strugnell, Tod, Gomila, Raul, Hamberger, John, Catalan, John, Ustyugova, Irina V, Farrell, Timothy, Stegalkina, Svetlana, Ray, Satyajit, LaRue, Lauren, Saelens, Xavier, Vogel, Thorsten U

“…Human H3N2 influenza viruses are subject to rapid antigenic evolution which translates into frequent updates of the composition of seasonal influenza vaccines…”
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Vaccination using melanoma cells treated with p19arf and interferon beta gene transfer in a mouse model: a novel combination for cancer immunotherapy by Medrano, Ruan Felipe Vieira, Catani, João Paulo Portela, Ribeiro, Aline Hunger, Tomaz, Samanta Lopes, Merkel, Christian A., Costanzi-Strauss, Eugenia, Strauss, Bryan E.

“…Previously, we combined p19 Arf ( Cdkn2a , tumor suppressor protein) and interferon beta (IFN-β, immunomodulatory cytokine) gene transfer in order to enhance…”
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Pre-existing antibodies directed against a tetramerizing domain enhance the immune response against artificially stabilized soluble tetrameric influenza neuraminidase by Catani, João Paulo Portela, Job, Emma R., Ysenbaert, Tine, Smet, Anouk, Ray, Satyajit, LaRue, Lauren, Stegalkina, Svetlana, Barro, Mario, Vogel, Thorsten U., Saelens, Xavier

“…The neuraminidase (NA) is an abundant antigen at the surface of influenza virions. Recent studies have highlighted the immune-protective potential of NA…”
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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models by Schepens, Bert, van Schie, Loes, Nerinckx, Wim, Roose, Kenny, Van Breedam, Wander, Fijalkowska, Daria, Devos, Simon, Weyts, Wannes, De Cae, Sieglinde, Vanmarcke, Sandrine, Lonigro, Chiara, Eeckhaut, Hannah, Van Herpe, Dries, Borloo, Jimmy, Oliveira, Ana Filipa, Catani, João Paulo Portela, Creytens, Sarah, De Vlieger, Dorien, Michielsen, Gitte, Marchan, Jackeline Cecilia Zavala, Moschonas, George D, Rossey, Iebe, Sedeyn, Koen, Van Hecke, Annelies, Zhang, Xin, Langendries, Lana, Jacobs, Sofie, Ter Horst, Sebastiaan, Seldeslachts, Laura, Liesenborghs, Laurens, Boudewijns, Robbert, Thibaut, Hendrik Jan, Dallmeier, Kai, Velde, Greetje Vande, Weynand, Birgit, Beer, Julius, Schnepf, Daniel, Ohnemus, Annette, Remory, Isabel, Foo, Caroline S, Abdelnabi, Rana, Maes, Piet, Kaptein, Suzanne J F, Rocha-Pereira, Joana, Jochmans, Dirk, Delang, Leen, Peelman, Frank, Staeheli, Peter, Schwemmle, Martin, Devoogdt, Nick, Tersago, Dominique, Germani, Massimiliano, Heads, James, Henry, Alistair, Popplewell, Andrew, Ellis, Mark, Brady, Kevin, Turner, Alison, Dombrecht, Bruno, Stortelers, Catelijne, Neyts, Johan, Callewaert, Nico, Saelens, Xavier

“…Broadly neutralizing antibodies are an important treatment for individuals with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome…”
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Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine by Zhong, Zifu, Portela Catani, João Paulo, Mc Cafferty, Séan, Couck, Liesbeth, Van Den Broeck, Wim, Gorlé, Nina, Vandenbroucke, Roosmarijn E, Devriendt, Bert, Ulbert, Sebastian, Cnops, Lieselotte, Michels, Johan, Ariën, Kevin K, Sanders, Niek N

“…To combat emerging infectious diseases like Zika virus (ZIKV), synthetic messenger RNAs (mRNAs) encoding viral antigens are very attractive as they allow a…”
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Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs by Zhong, Zifu, McCafferty, Séan, Opsomer, Lisa, Wang, Haixiu, Huysmans, Hanne, De Temmerman, Joyca, Lienenklaus, Stefan, Portela Catani, João Paulo, Combes, Francis, Sanders, Niek N.

“…Synthetic mRNAs are an appealing platform with multiple biomedical applications ranging from protein replacement therapy to vaccination. In comparison with…”
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CCL2/CCR2-Dependent Recruitment of Functional Antigen-Presenting Cells into Tumors upon Chemotherapy by YUTING MA, MATTAROLLO, Stephen R, YIDAN WANG, SISTIGU, Antonella, SCHULTZE, Joachim L, STOLL, Gautier, GALLUZZI, Lorenzo, ZITVOGEL, Laurence, SMYTH, Mark J, KROEMER, Guido, ADJEMIAN, Sandy, HENG YANG, AYMERIC, Laetitia, HANNANI, Dalil, PORTELA CATANI, João Paulo, DURET, Helene, TENG, Michele W. L, KEPP, Oliver

“…The therapeutic efficacy of anthracyclines relies, at least partially, on the induction of a dendritic cell- and T-lymphocyte-dependent anticancer immune…”
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ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy by Ma, Yuting, Adjemian, Sandy, Yang, Heng, Catani, João Paulo Portela, Hannani, Dalil, Martins, Isabelle, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Vacchelli, Erika, Galluzzi, Lorenzo, Zitvogel, Laurence, Kroemer, Guido

“…Tumor cells succumb to chemotherapy while releasing ATP. We have found that extracellular ATP attracts dendritic cell (DC) precursors into the tumor bed,…”
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Intratumoral Immunization by p19Arf and Interferon-β Gene Transfer in a Heterotopic Mouse Model of Lung Carcinoma by Catani, João Paulo Portela, Medrano, Ruan F.V, Hunger, Aline, Del Valle, Paulo, Adjemian, Sandy, Zanatta, Daniela Bertolini, Kroemer, Guido, Costanzi-Strauss, Eugenia, Strauss, Bryan E

“…Abstract Therapeutic strategies that act by eliciting and enhancing antitumor immunity have been clinically validated as an effective treatment modality but…”
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Near future of tumor immunology: Anticipating resistance mechanisms to immunotherapies, a big challenge for clinical trials by Catani, João Paulo Portela, Riechelmann, Rachel P., Adjemian, Sandy, Strauss, Bryan E.

“…The success of immunotherapies brings hope for the future of cancer treatment. Even so, we are faced with a new challenge, that of understanding which patients…”
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Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles–TLR7/8 Agonist Conjugates by Van Herck, Simon, Deswarte, Kim, Nuhn, Lutz, Zhong, Zifu, Portela Catani, Joao Paulo, Li, Yupeng, Sanders, Niek N, Lienenklaus, Stefan, De Koker, Stefaan, Lambrecht, Bart N, David, Sunil A, De Geest, Bruno G

“…Small molecule immuno-modulators such as agonists of Toll-like receptors (TLRs) are attractive compounds to stimulate innate immune cells toward potent…”
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Antibodies directed towards neuraminidase restrict influenza virus replication in primary human bronchial epithelial cells by Smet, Anouk, Catani, Joao Paulo Portela, Ysenbaert, Tine, Gonçalves, Amanda, Kleanthous, Harry, Vogel, Thorsten U, Saelens, Xavier, Job, Emma R

“…Influenza neuraminidase (NA) is implicated in various aspects of the virus replication cycle and therefore is an attractive target for vaccination and…”
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Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists by Yamazaki, T, Hannani, D, Poirier-Colame, V, Ladoire, S, Locher, C, Sistigu, A, Prada, N, Adjemian, S, Catani, J PP, Freudenberg, M, Galanos, C, André, F, Kroemer, G, Zitvogel, L

“…Immunogenic cell death induced by anticancer chemotherapy is characterized by a series of molecular hallmarks that include the exodus of high-mobility group…”
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The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017 by Catani, João Paulo Portela, Smet, Anouk, Ysenbaert, Tine, Vuylsteke, Marnik, Bottu, Guy, Mathys, Janick, Botzki, Alexander, Cortes-Garcia, Guadalupe, Strugnell, Tod, Gomila, Raul, Hamberger, John, Catalan, John, Ustyugova, Irina V, Farrell, Timothy, Stegalkina, Svetlana, Ray, Satyajit, LaRue, Lauren, Saelens, Xavier, Vogel, Thorsten U

“…Human H3N2 influenza viruses are subject to rapid antigenic evolution which translates into frequent updates of the composition of seasonal influenza vaccines…”
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Intratumoral Immunization by p19Arf and Interferon-β Gene Transfer in a Heterotopic Mouse Model of Lung Carcinoma12 by Catani, João Paulo Portela, Medrano, Ruan F.V., Hunger, Aline, Del Valle, Paulo, Adjemian, Sandy, Zanatta, Daniela Bertolini, Kroemer, Guido, Costanzi-Strauss, Eugenia, Strauss, Bryan E.

“…Therapeutic strategies that act by eliciting and enhancing antitumor immunity have been clinically validated as an effective treatment modality but may benefit…”
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Antibodies directed towards neuraminidase restrict influenza virus replication in primary human bronchial epithelial cells by Anouk Smet, Joao Paulo Portela Catani, Tine Ysenbaert, Amanda Gonçalves, Harry Kleanthous, Thorsten U. Vogel, Xavier Saelens, Emma R. Job

“…Influenza neuraminidase (NA) is implicated in various aspects of the virus replication cycle and therefore is an attractive target for vaccination and…”
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