Search Results - "Porras, Ana M"

Well-Defined Bifunctional Dendrimer Bearing 54 Nitric Oxide-Releasing Moieties and 54 Ursodeoxycholic Acid Groups Presenting High Anti-Inflammatory Activity by Garzón-Porras, Ana M., Bertuzzi, Diego L., Lucas, Kurt, Ornelas, Catia

“…Nitric oxide (NO) and ursodeoxycholic acid (UDCA) are endogenous molecules involved in physiological processes associated with inflammation. Since inflammatory…”
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Anti-inflammatory activity of polyamide dendrimers bearing bile acid termini synthesized via SPAAC by Garzón-Porras, Ana M., Bertuzzi, Diego L., Lucas, Kurt, Ornelas, Catia

“…Inflammation is a general pathomechanism associated with numerous diseases of global impact such as many cancers, metabolic disorders, and neurodegenerative…”
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Robust Generation of Quiescent Porcine Valvular Interstitial Cell Cultures by Porras, Ana M., Engeland, Nicole C. A., Marchbanks, Evelyn, McCormack, Ann, Bouten, Carlijn V. C., Yacoub, Magdi H., Latif, Najma, Masters, Kristyn S.

“…Background Valvular interstitial cells (VICs) in the healthy aortic valve leaflet exhibit a quiescent phenotype, with <5% of VICs exhibiting an activated…”
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Nitric Oxide Releasing Polyamide Dendrimer with Anti-inflammatory Activity by Garzón-Porras, Ana M, Bertuzzi, Diego L, Lucas, Kurt, da Silva, Laura C. E, de Oliveira, Marcelo G, Ornelas, Catia

“…Inflammatory processes are related to a wide variety of diseases with high global impact. Nitric oxide (NO) is an excellent candidate for the treatment of such…”
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Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease by Porras, Ana M., Westlund, Jennifer A., Evans, Austin D., Masters, Kristyn S.

“…An insufficient understanding of calcific aortic valve disease (CAVD) pathogenesis remains a major obstacle in developing treatment strategies for this…”
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Calcific Aortic Valve Disease by Porras, Ana M, McCoy, Chloé M, Masters, Kristyn S

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Calcific Aortic Valve Disease: A Battle of the Sexes by Porras, Ana M, McCoy, Chloé M, Masters, Kristyn S

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Engineering the aortic valve extracellular matrix through stages of development, aging, and disease by Scott, Ashley J., Simon, LaTonya R., Hutson, Heather N., Porras, Ana M., Masters, Kristyn S.

“…For such a thin tissue, the aortic valve possesses an exquisitely complex, multi-layered extracellular matrix (ECM), and disruptions to this structure…”
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Engineering approaches to study fibrosis in 3-D in vitro systems by Porras, Ana M, Hutson, Heather N, Berger, Anthony J, Masters, Kristyn S

“…Graphical abstract…”
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Gene expression profiling of valvular interstitial cells in Rapacz familial hypercholesterolemic swine by Porras, Ana M., Shanmuganayagam, Dhanansayan, Meudt, Jennifer J., Krueger, Christian G., Reed, Jess D., Masters, Kristyn S.

“…Rapacz familial hypercholesterolemic (RFH) swine is a well-established model of human FH, a highly prevalent hereditary disease associated with increased risk…”
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Building a virtual community to support and celebrate the success of Latinx scientists by Aguado, Brian A., Porras, Ana M.

“…In February 2019, we co-founded LatinXinBME to build a diverse and welcoming virtual community of Latinx researchers in biomedical engineering (BME). We…”
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Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification by Rodriguez, Karien J, Piechura, Laura M, Porras, Ana M, Masters, Kristyn S

“…Extracellular matrix (ECM) disarray is found in calcific aortic valvular disease (CAVD), yet much remains to be learned about the role of individual ECM…”
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Wave mice: a new tool in the quest to characterize aortic valvular disease etiologies by Porras, Ana M, Masters, Kristyn S

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Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology by Porras, Ana M, Shanmuganayagam, Dhanansayan, Meudt, Jennifer J, Krueger, Christian G, Hacker, Timothy A, Rahko, Peter S, Reed, Jess D, Masters, Kristyn S

“…Familial hypercholesterolemia (FH) is a prevalent hereditary disease associated with increased atherosclerosis and calcific aortic valve disease (CAVD)…”
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