Search Results - "Poretz, R D"

Rethinking cellular targets for lead neurotoxicity by Poretz, R.D.

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Lead Exposure Affects Levels of Galactolipid Metabolic Enzymes in the Developing Rat Brain by Deng, Wenbin, Poretz, R.D.

“…Lead poisoning is known to cause myelin defects. Galactolipids are the major lipid components of myelin and myelin-competent oligodendrocytes. The present…”
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Sites of Photodamage Induced by Photodynamic Therapy with a Chlorin e6 Triacetoxymethyl Ester (CAME) by Kessel, David, Poretz, R. D.

“…The acetoxymethyl ester of chlorin e6 (CAME) was initially designed to be a hydrophobic photosensitizing agent that would be recognized by an endocytic pathway…”
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The interaction of lead exposure and arylsulfatase A genotype affects sulfatide catabolism in human fibroblasts by Poretz, R D, Yang, A, Deng, W, Manowitz, P

“…Lead exposure causes cognitive and behavioral deficits in some affected children. We propose that a contributing mechanism for the neurological damage is that…”
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Antimutagenicity, cytotoxicity and composition of chlorophyllin copper complex by Chernomorsky, Simon, Rancourt, Raymond, Virdi, Kamalpreet, Segelman, Alvin, Poretz, Ronald D

“…The preparation of chlorophyllin copper complex (CCC), shown to be a tumor promoter in an animal model (Nelson, R.L. (1992) Chlorophyllin, an antimutagen, acts…”
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An acidic modification of the cytoplasmic domain contributes to the charge heterogeneity of the MHC class I antigens by Balomenos, D, Poretz, R D

“…Polypeptide phosphorylation and sialylation of the glycan moieties contribute to the charge heterogeneity of the class I major histocompatibility complex…”
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Association of alcoholism with the N-glycosylation polymorphism of pseudodeficient human arylsulfatase A by Park, D S, Poretz, R D, Stein, S, Nora, R, Manowitz, P

“…The IIIa and IIIb electrophoretic variants of arylsulfatase A (EC 3.1.6.8) are 12 times more prevalent in alcoholic than in nonalcoholic populations. These…”
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Pheophorbide a-induced photo-oxidation of cytochrome c: implication for photodynamic therapy by Chernomorsky, S, Wong, C, Poretz, R D

“…Pheophorbide a-induced photo-oxidation, in vitro, of cytochrome c oxidase and cytochrome c results in irreversible modifications to both protein components…”
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Metabolically convertible lipophilic derivatives of pH-sensitive amphipathic photosensitizers by Sahai, D, Lo, J L, Hagen, I K, Bergstrom, L, Chernomorsky, S, Poretz, R D

“…We propose the use of acetoxymethyl esters of pH-sensitive amphipathic photosensitizers (PS) for photodynamic therapy (PDT). These compounds may be applicable…”
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In-vitro photocytotoxicity of lysosomotropic immunoliposomes containing pheophorbide a with human bladder carcinoma cells by Bergstrom, L C, Vucenik, I, Hagen, I K, Chernomorsky, S A, Poretz, R D

“…Pheophorbide a is a photocytotoxic agent. To develop a tissue-specific, intracellularly targeted photoactive system, pheophorbide a was incorporated into…”
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The structural basis for the electrophoretic isoforms of normal and variant human platelet arylsulphatase A by PORETZ, R. D, RONG SHENG YANG, CANAS, B, LACKLAND, H, STEIN, S, MANOWITZ, P

“…Human platelet arylsulphatase A (ASA) exhibits a multiple banding pattern when examined by PAGE. The isoform pattern (IVa) of the enzyme obtained from normal…”
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Structural characterization of variant forms of arylsulfatase A that associate with alcoholism by Park, D S, Manowitz, P, Stein, S, Poretz, R D

“…Several electrophoretic forms of human platelet arylsulfatase A (ASA), including variant type IIIa and normal type IV(a), have been identified by nondenaturing…”
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Proteolytic processing of epidermal growth factor within endosomes by Schaudies, R P, Gorman, R M, Savage, Jr, C R, Poretz, R D

“…Following binding to its plasma membrane receptor, epidermal growth factor is transferred into three biochemically distinct endosomal compartments in a…”
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Resolution of multiple endosomal compartments associated with the internalization of epidermal growth factor and transferrin by Gorman, R M, Poretz, R D

“…Morphological studies have indicated divergent pathways for the endocytosis of epidermal growth factor (EGF) and transferrin (Tf). In order to obtain…”
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Hybrid myeloma cells which secrete heterodimetric IgG: A model to study the N‐linked glycan by LEE, S‐O., PORETZ, R. D.

“…Summary Fundamental questions remain unanswered regarding the effect of the acceptor polypeptide structure on the fine structure of the N‐linked glycan of…”
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Protein kinase C activation is required for the lead-induced inhibition of proliferation and differentiation of cultured oligodendroglial progenitor cells by Deng, Wenbin, Poretz, Ronald D.

“…Lead (Pb) is a common neurotoxicant of major public health concern. Previous studies revealed that cultured oligodendrocyte progenitor cells (OPCs) are highly…”
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A novel arylsulfatase A protein variant and genotype in two patients with major depression by Ricketts, Michael H., Amsterdam, Jay D., Park, David S., Yang, Rong-Sheng, Poretz, Ronald D., Zhang, Xiaoping, Fanale, Michelle, Baddoo, Andrew, Manowitz, Paul

“…A new, ‘diffuse, multiple banding’, electrophoretic variant of arylsulfatase A protein was found in two patients with major depression. Protein analyses showed…”
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The polypeptide of immunoglobulin G influences its galactosylation in vivo by SOO-OK LEE, J. M, CONNOLLY, J. M, RAMIREZ-SOTO, D, PORETZ, R. D

“…To examine the nature of the factors influencing the galactosylation pattern of the heavy chain of murine immunoglobulin G (IgG), cell fusion was performed…”
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Lead Exposure Delays the Differentiation of Oligodendroglial Progenitors in Vitro by Deng, Wenbin, McKinnon, Randall D., Poretz, Ronald D.

“…Lead (Pb) is an environmental neurotoxicant that can cause hypo- and demyelination. Oligodendrocytes (OLs), the myelin-forming cells in the central nervous…”
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Purification and properties of the hemagglutinin from Maclura pomifera seeds by Bausch, James N, Poretz, R. D

“…Maclura promifera seeds contain a protein which agglutinates human erythrocytes at concentrations as low as 4 ng/mL. This property is related to its ability to…”
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