Search Results - "Porchia, Bruna F. M. M"

Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice by Ramos da Silva, Jamile, Bitencourt Rodrigues, Karine, Formoso Pelegrin, Guilherme, Silva Sales, Natiely, Muramatsu, Hiromi, de Oliveira Silva, Mariângela, Porchia, Bruna F M M, Moreno, Ana Carolina Ramos, Aps, Luana Raposo M M, Venceslau-Carvalho, Aléxia Adrianne, Tombácz, István, Fotoran, Wesley Luzetti, Karikó, Katalin, Lin, Paulo J C, Tam, Ying K, de Oliveira Diniz, Mariana, Pardi, Norbert, de Souza Ferreira, Luís Carlos

“…As mRNA vaccines have proved to be very successful in battling the coronavirus disease 2019 (COVID-19) pandemic, this new modality has attracted widespread…”
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The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors by Moreno, Ana C R, Porchia, Bruna F M M, Pagni, Roberta L, Souza, Patrícia da Cruz, Pegoraro, Rafael, Rodrigues, Karine B, Barros, Tácita B, Aps, Luana R de Melo Moraes, de Araújo, Eliseu F, Calich, Vera L G, Ferreira, Luís C de Souza

“…Immunotherapy has become an important ally in the fight against distinct types of cancer. However, the metabolic plasticity of the tumor environment frequently…”
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Refolded dengue virus type 2 NS1 protein expressed in Escherichia coli preserves structural and immunological properties of the native protein by Amorim, Jaime Henrique, Porchia, Bruna F.M.M., Balan, Andrea, Cavalcante, Rafael C.M., da Costa, Simone Morais, de Barcelos Alves, Ada Maria, de Souza Ferreira, Luís Carlos

“…The dengue virus NS1 protein has been shown to be a protective antigen under different experimental conditions but the recombinant protein produced in…”
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Purified Herpes Simplex Type 1 Glycoprotein D (gD) Genetically Fused with the Type 16 Human Papillomavirus E7 Oncoprotein Enhances Antigen-Specific CD8+ T Cell Responses and Confers Protective Antitumor Immunity by Porchia, Bruna F. M. M, Diniz, Mariana O, Cariri, Francisco A. M. O, Santana, Vinícius C, Amorim, Jaime H, Balan, Andrea, Braga, Catarina J. M, Ferreira, Luís Carlos S

“…Type 1 herpes virus (HSV-1) glycoprotein D (gD) enhances antigen-specific immune responses, particularly CD8+ T cell responses, in mice immunized with DNA…”
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In vivo electroporation enhances vaccine-mediated therapeutic control of human papilloma virus-associated tumors by the activation of multifunctional and effector memory CD8+ T cells by Sales, Natiely S., Silva, Jamile R., Aps, Luana R.M.M., Silva, Mariângela O., Porchia, Bruna F.M.M., Ferreira, Luís Carlos S., Diniz, Mariana O.

“…In vivo electroporation (EP) has reignited the clinical interest on DNA vaccines as immunotherapeutic approaches to control different types of cancer. EP has…”
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Antigen Delivery to DEC205 + Dendritic Cells Induces Immunological Memory and Protective Therapeutic Effects against HPV-Associated Tumors at Different Anatomical Sites by Silva, Mariângela O, Almeida, Bianca S, Sales, Natiely S, Diniz, Mariana O, Aps, Luana R M M, Rodrigues, Karine B, Silva, Jamile R, Moreno, Ana C R, Porchia, Bruna F M M, Sulczewski, Fernando B, Boscardin, Silvia B, Ferreira, Luís C S

“…The generation of successful anticancer vaccines relies on the ability to induce efficient and long-lasting immune responses to tumor antigens. In this…”
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Herpes Simplex Virus Glycoprotein D Targets a Specific Dendritic Cell Subset and Improves the Performance of Vaccines to Human Papillomavirus-Associated Tumors by Porchia, Bruna F M M, Moreno, Ana Carolina R, Ramos, Rodrigo N, Diniz, Mariana O, de Andrade, Laís Helena T M, Rosa, Daniela S, Barbuto, José Alexandre M, Boscardin, Silvia B, Ferreira, Luís Carlos S

“…Cervical cancer is a major public health problem and one of the leading causes of cancer deaths in women. Virtually all cases of cervical cancer, as well as a…”
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Bacillus subtilis spores as adjuvants for DNA vaccines by Aps, Luana R.M.M, Diniz, Mariana O, Porchia, Bruna F.M.M, Sales, Natiely S, Moreno, Ana Carolina R, Ferreira, Luís C.S

“…Abstract Recently, Bacillus subtilis spores were shown to be endowed with strong adjuvant capacity when co-administered with purified antigenic proteins. In…”
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A therapeutic DNA vaccine and gemcitabine act synergistically to eradicate HPV-associated tumors in a preclinical model by Ramos da Silva, Jamile, Ramos Moreno, Ana Carolina, Silva Sales, Natiely, de Oliveira Silva, Mariângela, Aps, Luana R. M. M., Porchia, Bruna F.M.M., Bitencourt Rodrigues, Karine, Cestari Moreno, Natália, Venceslau-Carvalho, Aléxia Adrianne, Menck, Carlos Frederico M., de Oliveira Diniz, Mariana, de Souza Ferreira, Luís Carlos

“…Although active immunotherapies are effective strategies to induce activation of CD8 + T cells, advanced stage tumors require further improvements for…”
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Abstract B55: Targeting indoleamine 2,3 dioxygenase to improve the efficacy of a therapeutic vaccine against human papillomaviruses-associated tumors by Moreno, Ana Carolina Ramos, Porchia, Bruna F. M. M., Souza, Patrícia da Cruz, Pagni, Roberta Liberato, Pegoraro, Rafael, Ferreira, Luís Carlos de Souza

“…The activity of the enzyme indoleamine 2,3 dioxygenase-1 (IDO) has been associated with the maintenance of the immunosuppressive microenvironment in many types…”
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Abstract A62: In vivo electroporation improves the immune responses induced by a DNA vaccine and confers complete antitumor protection against HPV-associated tumors by Sales, Natiely Silva, Diniz, Mariana de Oliveira, Silva, Jamile Ramos, Silva, Mariângela de Oliveira, Porchia, Bruna F. M. M., Aps, Luana R. M. M., Ferreira, Luis Carlos Souza

“…Cervical cancer associated with persistent papilloma virus infections (HPV) is a public health problem and represents the third most frequent type of cancer in…”
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Role of bacteriophages in STEC infections: new implications for the design of prophylactic and treatment approaches by Amorim, Jaime H, Del Cogliano, Manuel E, Fernandez-Brando, Romina J, Bilen, Marcos F, Jesus, Monica R, Luiz, Wilson B, Palermo, Marina S, Ferreira, Rita C C, Servat, Esteban G, Ghiringhelli, Pablo D, Ferreira, Luis C S, Bentancor, Leticia V

“…Shiga toxin (Stx) is considered the main virulence factor in Shiga toxin-producing Escherichia coli (STEC) infections. Previously we reported the expression of…”
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