Search Results - "Popplewell, A."

BAlloon versus Stenting in severe Ischaemia of the Leg-3 (BASIL-3): study protocol for a randomised controlled trial by Hunt, Benjamin D, Popplewell, Matthew A, Davies, Huw, Meecham, Lewis, Jarrett, Hugh, Bate, Gareth, Grant, Margaret, Patel, Smitaa, Hewitt, Catherine, Andronis, Lazaros, Deeks, Jonathan J, Bradbury, Andrew

“…Severe limb ischaemia (SLI) is defined as the presence of rest pain and/or tissue loss secondary to lower extremity atherosclerotic peripheral arterial…”
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Ultra Boost for Economy: Extending the Limits of Extreme Engine Downsizing by Turner, J.W.G., Popplewell, A., Patel, R., Johnson, T.R., Darnton, N.J., Richardson, S., Bredda, S.W., Tudor, R.J., Bithell, C.I., Jackson, R., Remmert, S.M., Cracknell, R.F., Fernandes, J.X., Lewis, A.G.J., Akehurst, S., Brace, C.J., Copeland, C., Martinez-Botas, R., Romagnoli, A., Burluka, A.A.

“…The paper discusses the concept, design and final results from the ‘Ultra Boost for Economy’ collaborative project, which was part-funded by the Technology…”
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Comparison of Outcomes Following Infrapopliteal Plain Balloon Angioplasty in the BASIL Trial (1999-2004) and in a Contemporary Series (2009-2013) by Popplewell, Matthew A., Davies, Huw O.B., Renton, Mary, Bate, Gareth, Patel, Smitaa, Deeks, Jonathan J., Bradbury, Andrew W.

“…Objectives: To compare outcomes in patients randomized to infrapopliteal (IP) plain balloon angioplasty (PBA) for chronic limb-threatening ischemia within the…”
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A new technique to explant an infected aortic endograft by Popplewell, Matthew A., MRCS, MBChB, Garnham, Andrew W., FRCS, MB BCh, Hobbs, Simon D., FRCS, MD, BMedSc, MBChB

“…The management of an infected aortic endograft can be challenging both operatively and clinically. Although aortic endograft infection is rare, the incidence…”
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Comparing the surgical management of acute paediatric scrotal pain between adult urologists and general surgeons in the UK: an observational study by Bermingham, H N, Popplewell, M A, Naumann, D N, Gulamhussein, M A, Liaw, F, Layton, G R, Fernando, H, Tucker, O, Bowley, D, Dilworth, M P

“…Acute scrotal pain is a common paediatric surgical emergency. Assessment and timely exploration are required to rule out testicular torsion (TT) and prevent…”
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Octane Response in a Downsized, Highly Boosted Direct Injection Spark Ignition Engine by Remmert, S.M., Cracknell, R.F., Head, R., Schuetze, A., A.G.J., Lewis, Akehurst, S., Turner, J.W.G., Popplewell, A.

“…Increasingly strict government emissions regulations in combination with consumer demand for high performance vehicles is driving gasoline engine development…”
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Responses to the Main Critiques of the Bypass Versus Angioplasty in Severe Ischemia of the Leg (BASIL)-2 Trial by Popplewell, Matthew A., Bradbury, Andrew W.

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SuperGen on Ultraboost: Variable-Speed Centrifugal Supercharging as an Enabling Technology for Extreme Engine Downsizing by Turner, J.W.G., Popplewell, A., Marshall, D.J., Johnson, T.R., Barker, L., King, J., Martin, J., Lewis, A.G.J., Akehurst, S., Brace, C.J., Copeland, C.D.

“…The paper discusses investigations into improving the full-load and transient performance of the Ultraboost extreme downsizing engine by the application of the…”
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Bypass versus angio plasty in severe ischaemia of the leg - 2 (BASIL-2) trial: study protocol for a randomised controlled trial by Popplewell, Matthew A, Davies, Huw, Jarrett, Hugh, Bate, Gareth, Grant, Margaret, Patel, Smitaa, Mehta, Samir, Andronis, Lazaros, Roberts, Tracy, Deeks, Jon, Bradbury, Andrew

“…Severe limb ischaemia is defined by ischaemic rest/night pain, tissue loss, or both, secondary to arterial insufficiency and is increasingly caused by…”
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Formatting antibody fragments to mediate specific therapeutic functions by Weir, A N C, Nesbitt, A, Chapman, A P, Popplewell, A G, Antoniw, P, Lawson, A D G

“…Monoclonal antibodies are increasingly being used as therapeutic agents in a wide range of indications, including oncology, inflammation and infectious…”
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Procedural and 12-month in-hospital costs of primary infra-popliteal bypass surgery, infrapopliteal best endovascular treatment, and major lower limb amputation for chronic limb threatening ischemia by Popplewell, Matthew A., Andronis, Lazaros, Davies, Huw O.B., Meecham, Lewis, Kelly, Lisa, Bate, Gareth, Bradbury, Andrew W.

“…Chronic limb-threatening ischemia (CLTI) is a growing global problem due to the widespread use of tobacco and increasing prevalence of diabetes. Although the…”
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Editor's Choice – Bypass versus Angioplasty for Severe Ischaemia of the Leg (BASIL) Prospective Cohort Study and the Generalisability of the BASIL-2 Randomised Controlled Trial by Popplewell, Matthew A., Meecham, Lewis, Davies, Huw O.B., Kelly, Lisa, Ellis, Tracy, Bate, Gareth R., Moakes, Catherine A., Bradbury, Andrew W.

“…The Bypass versus Angioplasty in Severe Ischaemia of the Leg-2 (BASIL-2) randomised controlled trial has shown that, for patients with chronic limb threatening…”
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A Review of UK-based National and International Scientific Meeting Published Abstracts in Response to the Draft NICE Aortic Aneurysm Guidelines by Youssef, Sofian, Elkawafi, Mohamed, Peysner, Ryan, Popplewell, Matthew A, Rajagopalan, Sriram

“…Background: UK National Institute for Health and Care Excellence (NICE) draft clinical guidelines (CG) (2018) regarding aortic aneurysm repair were disputed…”
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A Comparison of Outcomes in Patients with Infrapopliteal Disease Randomised to Vein Bypass or Plain Balloon Angioplasty in the Bypass vs. Angioplasty in Severe Ischaemia of the Leg (BASIL) Trial by Popplewell, M.A, Davies, H.O.B, Narayanswami, J, Renton, M, Sharp, A, Bate, G, Patel, S, Deeks, J, Bradbury, A.W

“…Objective The aim was to compare outcomes in a subgroup of patients with infrapopliteal (IP) disease randomised to infrapopliteal vein bypass (VB) or plain…”
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A vascular multi-arm multi-stage trial to prevent groin wound surgical site infection: A feasibility survey by Popplewell, Matthew A, Gwilym, Brenig L, Benson, Ruth A, Juszczak, Maciej, Bosanquet, David, Pinkney, Thomas D, Chetter, Ian, Wall, Michael

“…Surgical site infection (SSI) is common following arterial surgery involving a groin incision. There is a lack of evidence regarding interventions to prevent…”
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Why Do Health Systems Not Fund Supervised Exercise Programmes for Intermittent Claudication? by Popplewell, M.A, Bradbury, A.W

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In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes by Berry, L.M., Adams, R., Airey, M., Bracher, M.G., Bourne, T., Carrington, B., Cross, A.S., Davies, G.C.G., Finney, H.M., Foulkes, R., Gozzard, N., Griffin, R.A., Hailu, H., Lamour, S.D., Lawson, A.D., Lightwood, D.J., McKnight, A.J., O'Dowd, V.L., Oxbrow, A.K.F., Popplewell, A.G., Shaw, S., Stephens, P.E., Sweeney, B., Tomlinson, K.L., Uhe, C., Palframan, R.T.

“…Interleukin-13 (IL-13) sequentially binds to IL-13Rα1 and IL-4Rα forming a high affinity signalling complex. This receptor complex is expressed on multiple…”
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Prolonged in Vivo Residence Times of Antibody Fragments Associated with Albumin by Smith, Bryan J, Popplewell, Andrew, Athwal, Dee, Chapman, Andrew P, Heywood, Sam, West, Shauna M, Carrington, Bruce, Nesbitt, Andrew, Lawson, Alastair D. G, Antoniw, Pari, Eddelston, Alison, Suitters, Amanda

“…Antibody fragments can be expressed at a high level in microbial systems, but they may have limited therapeutic value because they are rapidly eliminated from…”
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A Comparison of Contemporary Clinical Outcomes Following Femoro-Popliteal Plain Balloon Angioplasty and Bypass Surgery for Chronic Limb Threatening Ischemia by Meecham, Lewis, Popplewell, Mathew A., Bate, Gareth R., Patel, Smitaa, Bradbury, Andrew W.

“…Introduction: Despite the BASIL-1 trial concluding that bypass surgery (BS) was superior to plain balloon angioplasty (PBA) in terms of longer-term amputation…”
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Comparison of Clinical Outcomes in Patients Selected for Infra-Popliteal Bypass or Plain Balloon Angioplasty for Chronic Limb Threatening Ischemia Between 2009 and 2013 by Popplewell, Matthew A., Davies, Huw O. B., Meecham, Lewis, Bate, Gareth, Bradbury, Andrew W.

“…Introduction: A published subgroup analysis of the Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL)-1 trial suggests that, in patients with…”
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