Search Results - "Poppe, Laszlo"
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Tailoring the Spacer Arm for Covalent Immobilization of Candida antarctica Lipase B-Thermal Stabilization by Bisepoxide-Activated Aminoalkyl Resins in Continuous-Flow Reactors
Published in Molecules (Basel, Switzerland) (01-06-2016)“…An efficient and easy-to-perform method was developed for immobilization of CaLB on mesoporous aminoalkyl polymer supports by bisepoxide activation…”
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2
Enantiocomplementary Bioreduction of 1-(Arylsulfanyl)propan-2-ones
Published in Molecules (Basel, Switzerland) (15-08-2024)“…This study explored the enantiocomplementary bioreduction of substituted 1-(arylsulfanyl)propan-2-ones in batch mode using four wild-type yeast strains and two…”
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3
Additives enhancing the catalytic properties of lipase from Burkholderia cepacia immobilized on mixed-function-grafted mesoporous silica gel
Published in Molecules (Basel, Switzerland) (08-07-2014)“…Effects of various additives on the lipase from Burkholderia cepacia (BcL) immobilized on mixed-function-grafted mesoporous silica gel support by hydrophobic…”
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4
Chemoenzymatic Dynamic Kinetic Resolution of Amines in Fully Continuous-Flow Mode
Published in Organic letters (21-12-2018)“…In this study, lipase-mediated dynamic kinetic resolution (DKR) of various benzylic amines (1a–g) is presented which is realized in a so far unprecedented…”
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5
The Fourth Wave of Biocatalysis Emerges— The 13th International Symposium on Biocatalysis and Biotransformations
Published in Chembiochem : a European journal of chemical biology (16-02-2018)“…Ride the wave! Biocatalysis uses nature's catalysts, enzymes and whole cell systems, for synthetic purposes. In a biotransformation, the biocatalyst transforms…”
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6
Substrate Tunnel Engineering Aided by X‑ray Crystallography and Functional Dynamics Swaps the Function of MIO-Enzymes
Published in ACS catalysis (16-04-2021)“…The enzyme family harboring the post-translationally formed 5-methylene-3,5-dihydro-4H-imidazol-4-one (MIO) catalytic residue comprises both aromatic amino…”
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7
Tailoring the Spacer Arm for Covalent Immobilization of Candida antarctica Lipase B-Thermal Stabilization by Bisepoxide-Activated Aminoalkyl Resins in Continuous-Flow Reactors
Published in Molecules (Basel, Switzerland) (13-06-2016)“…An efficient and easy-to-perform method was developed for immobilization of CaLB on mesoporous aminoalkyl polymer supports by bisepoxide activation…”
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8
Design and application of a bi-functional redox biocatalyst through covalent co-immobilization of ene-reductase and glucose dehydrogenase
Published in Journal of biotechnology (10-11-2020)“…[Display omitted] •A bi-functional redox biocatalyst was obtained by co-immobilization of ene-reductase and glucose dehydrogenase.•The bi-functional…”
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9
Step-Economic Synthesis of Tamsulosin Hydrochloride via Continuous Chlorosulfonation and Biocatalytic Transamination
Published in Organic process research & development (11-11-2024)Get full text
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10
Isopropyl 2-ethoxyacetate—an efficient acylating agent for lipase-catalyzed kinetic resolution of amines in batch and continuous-flow modes
Published in Tetrahedron (17-11-2016)“…Productivity [conversion (c) and specific reaction rate (rbatch or rflow)] and enantiomer selectivity [enantiomeric ratio (E) and enantiomeric excess (ee) of…”
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11
Upgrading Epoxy Supports for Enzyme Immobilization by Affinity Function Doping—A Case Study with Phenylalanine Ammonia-Lyase from Petroselinum crispum
Published in Catalysts (01-01-2024)“…This article provides a method to upgrade epoxy-functionalized carriers for covalent enzyme immobilization to selective carriers suitable for covalent…”
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12
Transaminase-mediated synthesis of enantiopure drug-like 1-(3′,4′-disubstituted phenyl)propan-2-amines
Published in RSC advances (10-11-2020)“…Transaminases (TAs) offer an environmentally and economically attractive method for the direct synthesis of pharmaceutically relevant disubstituted…”
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13
Mapping the Hydrophobic Substrate Binding Site of Phenylalanine Ammonia-Lyase from Petroselinum crispum
Published in ACS catalysis (06-09-2019)“…Modification of the hydrophobic binding pocket of phenylalanine ammonia-lyase from Petroselinum crispum (PcPAL) enables increased activity and selectivity…”
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14
A novel phenylalanine ammonia-lyase from Pseudozyma antarctica for stereoselective biotransformations of unnatural amino acids
Published in Catalysis today (15-04-2021)“…[Display omitted] •Novel phenylalanine ammonia-lyase for the production of unnatural amino acids.•Superior turnover numbers compared to known phenylalanine…”
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15
Novel Sol-Gel Lipases by Designed Bioimprinting for Continuous-Flow Kinetic Resolutions
Published in Advanced synthesis & catalysis (01-09-2011)“…The bioimprinting effect in sol‐gel immobilization of lipases was studied to develop efficient novel immobilized biocatalysts with significantly improved…”
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16
Optimization Workflow of Fumonisin Esterase Production for Biocatalytic Degradation of Fumonisin B1
Published in Life (Basel, Switzerland) (08-09-2023)“…Industrial enzyme production with the Pichia pastoris expression system requires a well-characterized production strain and a competitively priced fermentation…”
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17
Phenylalanine Ammonia-Lyase-Catalyzed Deamination of an Acyclic Amino Acid: Enzyme Mechanistic Studies Aided by a Novel Microreactor Filled with Magnetic Nanoparticles
Published in Chembiochem : a European journal of chemical biology (02-11-2015)“…Phenylalanine ammonia‐lyase (PAL), found in many organisms, catalyzes the deamination of l‐phenylalanine (Phe) to (E)‐cinnamate by the aid of its MIO…”
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18
"Fishing and Hunting"-Selective Immobilization of a Recombinant Phenylalanine Ammonia-Lyase from Fermentation Media
Published in Molecules (Basel, Switzerland) (15-11-2019)“…This article overviews the numerous immobilization methods available for various biocatalysts such as whole-cells, cell fragments, lysates or enzymes which do…”
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19
Exploring the substrate scope of ferulic acid decarboxylase (FDC1) from Saccharomyces cerevisiae
Published in Scientific reports (24-01-2019)“…Ferulic acid decarboxylase from Saccharomyces cerevisiae ( Sc FDC1) was described to possess a novel, prenylated flavin mononucleotide cofactor (prFMN)…”
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20
Optimization of 2-alkoxyacetates as acylating agent for enzymatic kinetic resolution of chiral amines
Published in Tetrahedron (05-07-2018)“…In this study, the activity of acetic acid esters modified with electron withdrawing 2-alkoxy-groups was investigated as acylating agent in kinetic resolution…”
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