Search Results - "Popowych, Y."

Intrauterine immunizations trigger antigen-specific mucosal and systemic immunity in pigs and passive protection in suckling piglets by Choudhary, P., Fourie, K.R., Ng, S., Hamonic, G., Bérubé, N., Popowych, Y., Wilson, H.L.

“…•Vaccines can be administered to the pig uterus during breeding.•Subunit vaccines formulated with select adjuvants do not affect sperm function or pig…”
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In vivo immunostimulatory effects of CpG oligodeoxynucleotide in cattle and sheep by Nichani, A.K, Mena, A, Popowych, Y, Dent, D, Townsend, H.G.G, Mutwiri, G.K, Hecker, R, Babiuk, L.A, Griebel, P.J

“…Oligodeoxynucleotides (ODN) containing cytosine–phosphate–guanosine (CpG) motifs have been shown to activate the innate immune system and protect mice and…”
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Cytokine profiles following interaction between bovine alveolar macrophages and Pasteurella haemolytica by Morsey, M.A, Van Kessel, A.G, Mori, Y, Popowych, Y, Godson, D, Campos, M, Babiuk, L.A

“…Pasteurella haemolytica is a gram negative bacterium frequently isolated from the lungs of calves suffering from a fibrinous pneumonic condition known as…”
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Lymphocyte proliferative responses to recombinant bovine herpes virus type 1 (BHV-1) glycoprotein gD (gIV) in immune cattle: identification of a T cell epitope by Tikoo, S K, Campos, M, Popowych, Y I, van Drunen Littel-van den Hurk, S, Babiuk, L A

“…The lymphocyte proliferative response to BHV-1 in immune cattle was compared to recombinant wild-type gD and truncated gD produced from recombinant vaccinia…”
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Cytokine profiles following interaction between bovine alveolar macrophages and by Morsey, M.A., Van-Kessel, A.G., Mori, Y., Popowych, Y., Godson, D., Campos, M., Babiuk, L.A.

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Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide by Mookherjee, Neeloffer, Wilson, Heather L., Doria, Silvana, Popowych, Yurij, Falsafi, Reza, Yu, Jie (Jessie), Li, YueXin, Veatch, Sarah, Roche, Fiona M., Brown, Kelly L., Brinkman, Fiona S. L., Hokamp, Karsten, Potter, Andy, Babiuk, Lorne A., Griebel, Philip J., Hancock, Robert E. W.

“…Genomic approaches can be exploited to expose the complexities and conservation of biological systems such as the immune network across various mammalian…”
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Effect of chronic administration of recombinant bovine tumor necrosis factor to cattle by Bielefeldt Ohmann, H, Campos, M, Snider, M, Rapin, N, Beskorwayne, T, Popowych, Y, Lawman, M J, Rossi, A, Babiuk, L A

“…Cachectin/tumor necrosis factor-alpha (TNF), a protein produced by macrophages upon stimulation, has been implicated as an important mediator of inflammatory…”
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Molecular cloning and expression of bovine interleukin-8 by Morsey, Mohamad A., Popowych, Yurij, Kowalski, Jacek, Gerlach, Gerald, Godson, Dale, Campos, Manuel, Babiuk, L.A.

“…Interleukin-8 (IL-8) is a neutrophil and T-lymphocyte chemotactic and activating factor. This cytokine is produced by many cell types including macrophages in…”
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Bovine toll-like receptor 9: A comparative analysis of molecular structure, function and expression by Griebel, Philip J., Brownlie, Robert, Manuja, Anju, Nichani, Anil, Mookherjee, Neeloffer, Popowych, Yurij, Mutwiri, George, Hecker, Rolf, Babiuk, Lorne A.

“…Non-methylated CpG motifs, present in viral and bacterial DNA, are one of many pathogen-associated molecular patterns (PAMP) recognized by the mammalian innate…”
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Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells by Mena, Angelo, Nichani, Anil K., Popowych, Yurij, Godson, Dale L., Dent, Donna, Townsend, Hugh G. G., Mutwiri, George K., Hecker, Rolf, Babiuk, Lorne A., Griebel, Philip

“…Summary Examples exist in the literature that demonstrate that treatment with immunostimulatory cytosine–phosphate–guanosine (CpG)‐DNA can protect mice against…”
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Th1/Th2 biasing effects of vaccination in cattle as determined by real-time PCR by Mena, Angelo, Ioannou, Xenia P., Van Kessel, Andrew, Van Drunen Little-Van Den Hurk, Sylvia, Popowych, Yurij, Babiuk, Lorne A., Godson, Dale L.

“…Real-time polymerase chain reaction (PCR) is now becoming an accepted tool for measuring gene expression at the transcriptional level. In this study, a direct…”
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CpG oligodeoxynucleotide induction of antiviral effector molecules in sheep by Nichani, Anil K., Kaushik, Radhey S., Mena, Angelo, Popowych, Yurij, Dent, Donna, Townsend, Hugh G.G., Mutwiri, George, Hecker, Rolf, Babiuk, Lorne A., Griebel, Philip J.

“…Immunostimulatory CpG oligodeoxynucleotide (ODN) can protect mice against infection by many pathogens but the mechanisms mediating disease protection are not…”
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Cloning non-transformed sheep B cells by Griebel, Philip J, Beskorwayne, Terry, Godson, Dale L, Popowych, Yurij, Hein, Wayne

“…The capacity to clone B cells and establish permanent B cell lines has greatly facilitated a wide variety of studies characterising the growth,…”
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Cytokine profiles following interaction between bovine alveolar macrophages andPasteurella haemolytica by Morsey, M.A., Van-Kessel, A.G., Mori, Y., Popowych, Y., Godson, D., Campos, M., Babiuk, L.A.

“…Pasteurella haemolyticais a Gram negative bacterium frequently isolated from the lungs of calves suffering from a fibrinous pneumonic condition known as…”
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Bovine and ovine blood mononuclear leukocytes differ markedly in innate immune responses induced by Class A and Class B CpG-oligodeoxynucleotide by Mena, Angelo, Nichani, Anil K, Popowych, Yurij, Ioannou, Xenia P, Godson, Dale L, Mutwiri, George K, Hecker, Rolf, Babiuk, Lorne A, Griebel, Philip

“…Cytosine-phosphate-guanosine (CpG)-DNA can induce an impressive array of innate immune responses that may directly or indirectly contribute to the clearance of…”
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