Search Results - "Popovic, Marko A"
-
1
Saltatory Conduction along Myelinated Axons Involves a Periaxonal Nanocircuit
Published in Cell (23-01-2020)“…The propagation of electrical impulses along axons is highly accelerated by the myelin sheath and produces saltating or “jumping” action potentials across…”
Get full text
Journal Article -
2
The spatio‐temporal characteristics of action potential initiation in layer 5 pyramidal neurons: a voltage imaging study
Published in The Journal of physiology (01-09-2011)“…Non‐technical summary Axons are long process of nerve cells that mediate communication and control within the organism. Mammalian neurons have developed a…”
Get full text
Journal Article -
3
Dependence of STIM1/Orai1-mediated Calcium Entry on Plasma Membrane Phosphoinositides
Published in The Journal of biological chemistry (31-07-2009)“…Recent studies identified two main components of store-operated calcium entry (SOCE): the endoplasmic reticulum-localized Ca2+ sensor protein, STIM1, and the…”
Get full text
Journal Article -
4
The stochastic nature of action potential backpropagation in apical tuft dendrites
Published in Journal of neurophysiology (01-08-2017)“…In cortical pyramidal neurons, backpropagating action potentials (bAPs) supply Ca to synaptic contacts on dendrites. To determine whether the efficacy of AP…”
Get full text
Journal Article -
5
FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State
Published in Cancers (10-09-2020)“…Cancer stem cells (CSCs) are located in dedicated niches, where they remain inert to chemotherapeutic drugs and drive metastasis. Although plasticity in the…”
Get full text
Journal Article -
6
A Versatile and Open-Source Rapid LED Switching System for One-Photon Imaging and Photo-Activation
Published in Frontiers in cellular neuroscience (17-01-2019)“…Combining fluorescence and transmitted light sources for microscopy is an invaluable method in cellular neuroscience to probe the molecular and cellular…”
Get full text
Journal Article -
7
Sarcomere Disassembly and Transfection Efficiency in Proliferating Human iPSC-Derived Cardiomyocytes
Published in Journal of cardiovascular development and disease (27-01-2022)“…Contractility of the adult heart relates to the architectural degree of sarcomeres in individual cardiomyocytes (CMs) and appears to be inversely correlated…”
Get full text
Journal Article -
8
Electrical behaviour of dendritic spines as revealed by voltage imaging
Published in Nature communications (05-10-2015)“…Thousands of dendritic spines on individual neurons process information and mediate plasticity by generating electrical input signals using a sophisticated…”
Get full text
Journal Article -
9
High-Frequency Microdomain Ca2+ Transients and Waves during Early Myelin Internode Remodeling
Published in Cell reports (Cambridge) (02-01-2019)“…Ensheathment of axons by myelin is a highly complex and multi-cellular process. Cytosolic calcium (Ca2+) changes in the myelin sheath have been implicated in…”
Get full text
Journal Article -
10
Multiple Roles of Gi/o Protein-coupled Receptors in Control of Action Potential Secretion Coupling in Pituitary Lactotrophs
Published in Annals of the New York Academy of Sciences (01-01-2009)“…Gi/o protein‐coupled receptors, signaling through G protein‐dependent and protein‐independent pathways, have prominent effects on secretion by modulating…”
Get full text
Journal Article -
11
Loss of Saltation and Presynaptic Action Potential Failure in Demyelinated Axons
Published in Frontiers in cellular neuroscience (27-02-2017)“…In cortical pyramidal neurons the presynaptic terminals controlling transmitter release are located along unmyelinated axon collaterals, far from the original…”
Get full text
Journal Article -
12
Cortical dendritic spine heads are not electrically isolated by the spine neck from membrane potential signals in parent dendrites
Published in Cerebral cortex (New York, N.Y. 1991) (01-02-2014)“…The evidence for an important hypothesis that cortical spine morphology might participate in modifying synaptic efficacy that underlies plasticity and possibly…”
Get full text
Journal Article -
13
Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling
Published in eLife (17-06-2020)“…Calcium ions (Ca 2+ ) are essential for many cellular signaling mechanisms and enter the cytosol mostly through voltage-gated calcium channels. Here, using…”
Get full text
Journal Article -
14
Imaging with organic indicators and high-speed charge-coupled device cameras in neurons: some applications where these classic techniques have advantages
Published in Neurophotonics (Print) (01-04-2015)“…Dynamic calcium and voltage imaging is a major tool in modern cellular neuroscience. Since the beginning of their use over 40 years ago, there have been major…”
Get full text
Journal Article -
15
Ca.sup.2+ entry through Na.sub.V channels generates submillisecond axonal Ca.sup.2+ signaling
Published in eLife (17-06-2020)“…Calcium ions (Ca.sup.2+) are essential for many cellular signaling mechanisms and enter the cytosol mostly through voltage-gated calcium channels. Here, using…”
Get full text
Journal Article -
16
Ca 2+ entry through Na V channels generates submillisecond axonal Ca 2+ signaling
Published in eLife (17-06-2020)“…Calcium ions (Ca ) are essential for many cellular signaling mechanisms and enter the cytosol mostly through voltage-gated calcium channels. Here, using…”
Get full text
Journal Article -
17
High-Frequency Microdomain Ca 2+ Transients and Waves during Early Myelin Internode Remodeling
Published in Cell reports (Cambridge) (02-01-2019)“…Ensheathment of axons by myelin is a highly complex and multi-cellular process. Cytosolic calcium (Ca ) changes in the myelin sheath have been implicated in…”
Get full text
Journal Article -
18
Multiple Roles of G sub(i/o) Protein-coupled Receptors in Control of Action Potential Secretion Coupling in Pituitary Lactotrophs
Published in Annals of the New York Academy of Sciences (01-01-2009)“…G sub(i/o) protein-coupled receptors, signaling through G protein-dependent and protein-independent pathways, have prominent effects on secretion by modulating…”
Get full text
Journal Article -
19
Multiple Roles of G i/o Protein‐coupled Receptors in Control of Action Potential Secretion Coupling in Pituitary Lactotrophs
Published in Annals of the New York Academy of Sciences (01-01-2009)“…G i/o protein‐coupled receptors, signaling through G protein‐dependent and protein‐independent pathways, have prominent effects on secretion by modulating…”
Get full text
Journal Article