Search Results - "Popova, Galina P"
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Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies
Published in Molecules (Basel, Switzerland) (01-01-2023)“…Fluorescent antibodies have proved to be an invaluable tool for molecular biology and diagnostics. They are routinely produced by modification of lysine…”
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Aminooxy Click Modification of a Periodate-Oxidized Immunoglobulin G: A General Approach to Antibody-Drug Conjugates with Dye-Mediated Expeditious Stoichiometry Control
Published in International journal of molecular sciences (01-03-2023)“…A universal approach to the construction of antibody-drug conjugates (ADCs) has been developed. It relies on periodate oxidation of naturally present glycans…”
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Sensitive Immunofluorescent Detection of the PRAME Antigen Using a Practical Antibody Conjugation Approach
Published in International journal of molecular sciences (27-11-2021)“…Bioconjugation of antibodies with various payloads has diverse applications across various fields, including drug delivery and targeted imaging techniques…”
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Synthesis and Comparison of the Reactivity of 3,4,5-1H-Trinitropyrazole and Its N-Methyl Derivative
Published in Journal of heterocyclic chemistry (01-07-2013)“…3,4,5‐Trinitro‐1H‐pyrazole (1) has been obtained via nitration of 3,5‐dinitropyrazole with mixture of sulfuric and nitric acids. Compound 1 reacts with excess…”
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The specific reactivity of 3,4,5-trinitro-1H-pyrazole
Published in Mendeleev communications (01-09-2010)“…Nitration of 3,5-dinitropyrazole with HNO3-H2SO4 mixture gives 3,4,5-trinitro-1H-pyrazole, which in reaction with ammonia, amines or thiols under mild…”
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Hydrogen halides as nucleophilic agents for 3,4,5-trinitro-1H-pyrazoles
Published in Mendeleev communications (01-01-2012)“…1-R-3,4,5-Trinitropyrazoles (R = H, Me) undergo nucleophilic substitution on treatment with concentrated hydrogen halide solutions to give…”
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Nucleophilic substitution in 1-methyl-3,4,5-trinitro-1H-pyrazole
Published in Mendeleev communications (01-05-2011)“…1-Methyl-3,4,5-trinitropyrazole in reaction with thiols, phenols, oximes, ammonia, amines and NH-azoles gives substitution products of the 5-positioned nitro…”
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N-Fluoro derivatives of nitrated pyrazole-containing fused heterocycles
Published in Mendeleev communications (01-01-2011)“…N-Fluorination of Na-salts of polynitrated bipyrazoles and pyrazole-based fused heterocycles with fluorine–nitrogen mixture (10% F 2) at −60 to −70 °C in MeOH…”
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Synthesis of 4-(N-azolyl)-3,5-dinitropyrazoles
Published in Mendeleev communications (01-11-2010)Get full text
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Nucleophilic substitution in 1-methyl-3,4,5-trinitro-1 H-pyrazole
Published in Mendeleev communications (2011)“…1-Methyl-3,4,5-trinitropyrazole in reaction with thiols, phenols, oximes, ammonia, amines and NH-azoles gives substitution products of the 5-positioned nitro…”
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12
The specific reactivity of 3,4,5-trinitro-1 H-pyrazole
Published in Mendeleev communications (2010)“…Nitration of 3,5-dinitropyrazole with HNO3–H2SO4 mixture gives 3,4,5-trinitro-1H-pyrazole, which in reaction with ammonia, amines or thiols under mild…”
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