Search Results - "Popov Aleksandrov, Aleksandra"
-
1
Impact of Skin Exposure to Benzo[a]pyrene in Rat Model: Insights into Epidermal Cell Function and Draining Lymph Node Cell Response
Published in International journal of molecular sciences (08-08-2024)“…The skin is a direct target of the air pollutant benzo[a]pyrene (BaP). While its carcinogenic qualities are well-studied, the immunotoxicity of BaP after…”
Get full text
Journal Article -
2
Acute cadmium administration to rats exerts both immunosuppressive and proinflammatory effects in spleen
Published in Toxicology (Amsterdam) (04-12-2014)“…Highlights • The effect of cadmium on splenic T and innate immune cells in rats is explored. • Differential effects of 1 mg/kg on T cell and innate immune…”
Get full text
Journal Article -
3
Effects of warfarin on biological processes other than haemostasis: A review
Published in Food and chemical toxicology (01-03-2018)“…Warfarin is the world's most widely used anticoagulant drug. Its anticoagulant activity is based on the inhibition of the vitamin K-dependent (VKD) step in the…”
Get full text
Journal Article -
4
Aryl Hydrocarbon Receptor is Involved in the Proinflammatory Cytokine Response to Cadmium
Published in Biomedical and environmental sciences (01-03-2021)“…To investigate involvement of the aryl hydrocarbon receptor (AhR) in the immunomodulatory effects of cadmium (Cd). The effect of Cd on AhR activation ( and…”
Get more information
Journal Article -
5
Gut microbial dysbiosis occurring during pulmonary fungal infection in rats is linked to inflammation and depends on healthy microbiota composition
Published in Microbiology spectrum (01-10-2023)“…ABSTRACT While the effect of gut microbiota and/or inflammation on a distant body site, including the lungs (gut–lung axis), has been well characterized, data…”
Get full text
Journal Article -
6
Subchronic Oral Cadmium Exposure Exerts both Stimulatory and Suppressive Effects on Pulmonary Inflammation/Immune Reactivity in Rats
Published in Biomedical and environmental sciences (01-07-2019)“…The aim of this study is to investigate the effects of oral cadmium (Cd) ingestion on the pulmonary immune response. Determination of Cd content in lungs and…”
Get more information
Journal Article -
7
Immunotoxicology of cadmium: Cells of the immune system as targets and effectors of cadmium toxicity
Published in Food and chemical toxicology (01-03-2021)“…Cadmium (Cd) has been listed as one of the most toxic substances affecting numerous tissues/organs, including the immune system. Due to variations in studies…”
Get full text
Journal Article -
8
Toxicity of oral cadmium intake: Impact on gut immunity
Published in Toxicology letters (02-09-2015)“…•Examination of the effect of oral cadmium intake on gut immune responses in rat.•Tissue damage and inflammation were evident in homogenates of…”
Get full text
Journal Article -
9
Pulmonary immune responses to Aspergillus fumigatus in rats
Published in Biomedical and environmental sciences (01-09-2014)“…To evaluate immunologic mechanisms underlying Aspergillus fumigatus pulmonary infections in immunocompetent Dark Agouti (DA) and Albino Oxford (AO) rats…”
Get more information
Journal Article -
10
Immunomodulation by heavy metals as a contributing factor to inflammatory diseases and autoimmune reactions: Cadmium as an example
Published in Immunology letters (01-12-2021)“…•Cd accumulation in organs could cause inflammatory / autoimmune reactions.•Cd-induced responses contribute to tissue/organ injury and dysfunction.•Such…”
Get full text
Journal Article -
11
Toxicology of chemical biocides: Anticoagulant rodenticides – Beyond hemostasis disturbance
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-03-2024)“…The use of anticoagulant rodenticides (ARs) is one of the most commonly employed management methods for pest rodents. ARs compete with vitamin K (VK) required…”
Get full text
Journal Article -
12
Cadmium and immunologically-mediated homeostasis of anatomical barrier tissues
Published in Toxicology letters (01-02-2021)“…[Display omitted] Cadmium (Cd) is a toxic heavy metal that when absorbed into the body causes nephrotoxicity and effects in other tissues.Anatomical barrier…”
Get full text
Journal Article -
13
Lung microbiota changes during pulmonary Aspergillus fumigatus infection in rats
Published in Microbes and infection (01-11-2023)“…Since the realization that the lungs are not sterile but are normally inhabited by various bacterial species, studies have been conducted to define healthy…”
Get full text
Journal Article -
14
Physiological strategies in wild rodents: immune defenses of commensal rats
Published in Integrative zoology (01-05-2024)“…The importance of issues associated with urban/commensal rats and mice (property damage, management costs, and health risks) press upon research on these…”
Get full text
Journal Article -
15
Strain differences in toxicity of vitamin K antagonist warfarin in rats
Published in Journal of the Serbian Chemical Society (01-01-2013)“…Warfarin (4-hydroxy coumarin) is Vitamin K (VK) antagonist that inhibits Vitamin K-dependent (VKD) processes, such as blood coagulation. It exerts influence on…”
Get full text
Journal Article -
16
Oral cadmium exposure affects skin immune reactivity in rats
Published in Ecotoxicology and environmental safety (30-11-2018)“…Skin can acquire cadmium (Cd) by oral route, but there is paucity of data concerning cutaneous effects of this metal. Cd acquired by oral route can affect skin…”
Get full text
Journal Article -
17
Proinflammatory effects of environmental cadmium boost resistance to opportunistic pathogen Aspergillus fumigatus: Implications for sustained low-level pulmonary inflammation?
Published in Toxicology (Amsterdam) (15-01-2021)“…•Cd does not affect the elimination of the A. fumigatus in immunocompetent rats.•Cd causes preservation and/or increase in innate immunity against the…”
Get full text
Journal Article -
18
Strain differences of cadmium-induced toxicity in rats: Insight from spleen and lung immune responses
Published in Toxicology letters (10-08-2016)“…•Strain differences in acute cadmium immunotoxicity are explored in DA and AO rats.•Cadmium affected spleen and lungs cells immune response in DA and AO…”
Get full text
Journal Article -
19
Orally Administrated Lactiplantibacillus plantarum BGAN8-Derived EPS-AN8 Ameliorates Cd Hazards in Rats
Published in International journal of molecular sciences (02-02-2023)“…Cadmium (Cd) is a highly toxic metal that is distributed worldwide. Exposure to it is correlated with a vast number of diseases and organism malfunctions…”
Get full text
Journal Article -
20
Dermatotoxicity of oral cadmium is strain-dependent and related to differences in skin stress response and inflammatory/immune activity
Published in Environmental toxicology and pharmacology (01-04-2020)“…•Oral Cd accumulates in rat skin and epidermal cells, without strain differences.•More pronounced oxidative and immune activity was noted in DA skin/epidermal…”
Get full text
Journal Article