Search Results - "Poplawski, Tomasz"

DNA Damage Response as a Pharmacological Target for Cancer and Infectious Diseases by Poplawski, Tomasz

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Responses of human colon and breast adenocarcinoma cell lines (LoVo, MCF7) and non-tumorigenic mammary epithelial cells (MCF-10A) to the acellular fraction of packed red blood cells in the presence and absence of cisplatin by Czubak-Prowizor, Kamila, Macieja, Anna, Poplawski, Tomasz, Zbikowska, Halina Malgorzata

“…Perioperative blood transfusion in colorectal and some other cancer patients has been linked to the increased risk for recurrence, but a causal mechanism…”
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Tryptophan Metabolism in Postmenopausal Women with Functional Constipation by Blonska, Aleksandra, Chojnacki, Marcin, Macieja, Anna, Blasiak, Janusz, Majsterek, Ireneusz, Chojnacki, Jan, Poplawski, Tomasz

“…Constipation belongs to conditions commonly reported by postmenopausal women, but the mechanism behind this association is not fully known. The aim of the…”
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A Reduced Tryptophan Diet in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Improves Their Abdominal Symptoms and Their Quality of Life through Reduction of Serotonin Levels and Its Urinary Metabolites by Chojnacki, Cezary, Medrek-Socha, Marta, Blonska, Aleksandra, Zajdel, Radoslaw, Chojnacki, Jan, Poplawski, Tomasz

“…(1). An essential component of any treatment for patients with irritable bowel syndrome (IBS) is an adequate diet. Currently, a low FODMAP diet is recommended…”
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The Usefulness of the Low-FODMAP Diet with Limited Tryptophan Intake in the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome by Chojnacki, Cezary, Poplawski, Tomasz, Blonska, Aleksandra, Konrad, Paulina, Chojnacki, Jan, Blasiak, Janusz

“…(1) Background: A low-FODMAP diet is often recommended in the treatment of irritable bowel syndrome, but it does not improve abdominal symptoms in all…”
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Ochratoxin A—The Current Knowledge Concerning Hepatotoxicity, Mode of Action and Possible Prevention by Więckowska, Magdalena, Szelenberger, Rafał, Niemcewicz, Marcin, Harmata, Piotr, Poplawski, Tomasz, Bijak, Michał

“…Ochratoxin A (OTA) is considered as the most toxic of the other ochratoxins synthesized by various fungal species belonging to the Aspergillus and Penicillium…”
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Exploring the Gene Expression and Plasma Protein Levels of HSP90, HSP60, and GDNF in Multiple Sclerosis Patients and Healthy Controls by Sokolowski, Igor, Kucharska-Lusina, Aleksandra, Miller, Elzbieta, Poplawski, Tomasz, Majsterek, Ireneusz

“…Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by immune-mediated inflammation and neurodegeneration in the central nervous…”
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The Association between Inefficient Repair of DNA Double-Strand Breaks and Common Polymorphisms of the HRR and NHEJ Repair Genes in Patients with Rheumatoid Arthritis by Galita, Grzegorz, Sarnik, Joanna, Brzezinska, Olga, Budlewski, Tomasz, Poplawska, Marta, Sakowski, Sebastian, Dudek, Grzegorz, Majsterek, Ireneusz, Makowska, Joanna, Poplawski, Tomasz

“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation affecting up to 2.0% of adults around the world. The molecular…”
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Machine learning-based prediction of rheumatoid arthritis with development of ACPA autoantibodies in the presence of non-HLA genes polymorphisms by Dudek, Grzegorz, Sakowski, Sebastian, Brzezińska, Olga, Sarnik, Joanna, Budlewski, Tomasz, Dragan, Grzegorz, Poplawska, Marta, Poplawski, Tomasz, Bijak, Michał, Makowska, Joanna

“…Machine learning (ML) algorithms can handle complex genomic data and identify predictive patterns that may not be apparent through traditional statistical…”
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Changes in Tryptophan Metabolism on Serotonin and Kynurenine Pathways in Patients with Irritable Bowel Syndrome by Chojnacki, Cezary, Błońska, Aleksandra, Konrad, Paulina, Chojnacki, Marcin, Podogrocki, Marcin, Poplawski, Tomasz

“…(1) Background: L-tryptophan is a substrate for the synthesis of many biological compounds through the serotonin and kynurenine pathways. These compounds have…”
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DNA Double Strand Breaks Repair Inhibitors: Relevance as Potential New Anticancer Therapeutics by Kopa, Paulina, Macieja, Anna, Galita, Grzegorz, Witczak, Zbigniew J, Poplawski, Tomasz

“…DNA double-strand breaks are considered one of the most lethal forms of DNA damage. Many effective anticancer therapeutic approaches used chemical and physical…”
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Altered Tryptophan Metabolism on the Kynurenine Pathway in Depressive Patients with Small Intestinal Bacterial Overgrowth by Chojnacki, Cezary, Konrad, Paulina, Błońska, Aleksandra, Medrek-Socha, Marta, Przybylowska-Sygut, Karolina, Chojnacki, Jan, Poplawski, Tomasz

“…The causes of depression are diverse and are still not fully understood. Recently, an increasing role is attributed to nutritional and inflammatory factors…”
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DNA Computing: Concepts for Medical Applications by Sakowski, Sebastian, Waldmajer, Jacek, Majsterek, Ireneusz, Poplawski, Tomasz

“…The branch of informatics that deals with construction and operation of computers built of DNA, is one of the research directions which investigates issues…”
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DNA double-strand breaks repair inhibitors potentiates the combined effect of VP-16 and CDDP in human colorectal adenocarcinoma (LoVo) cells by Kopa, Paulina, Macieja, Anna, Pastwa, Elzbieta, Majsterek, Ireneusz, Poplawski, Tomasz

“…I. Background: A combination of etoposide (VP-16) and cisplatin (CDDP) is the standard treatment for certain colon cancers. These drugs promote the death of…”
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Polymorphisms in DNA Repair Genes and Association with Rheumatoid Arthritis in a Pilot Study on a Central European Population by Galita, Grzegorz, Sarnik, Joanna, Brzezinska, Olga, Budlewski, Tomasz, Dragan, Grzegorz, Poplawska, Marta, Majsterek, Ireneusz, Poplawski, Tomasz, Makowska, Joanna S

“…Rheumatoid arthritis (RA) is a chronic, multifactorial autoimmune disease characterized by chronic arthritis, a tendency to develop joint deformities, and…”
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Tyrosine kinase blockers: new hope for successful cancer therapy by Pytel, Dariusz, Sliwinski, Tomasz, Poplawski, Tomasz, Ferriola, Deborah, Majsterek, Ireneusz

“…Tyrosine kinases (TKs) are attractive targets for cancer therapy, as quite often their abnormal signaling has been linked with tumor development and growth…”
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Association of polymorphic variants in GEMIN genes with the risk of depression in a Polish population by Kowalczyk, Mateusz, Kowalczyk, Edward, Gogolewska, Monika, Skrzypek, Maciej, Talarowska, Monika, Majsterek, Ireneusz, Poplawski, Tomasz, Kwiatkowski, Paweł, Sienkiewicz, Monika

“…The role of miRNA in depression is widely described by many researchers. miRNA is a final product of many genes involved in its formation (maturation). One of…”
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Genotoxicity and cytotoxicity of 2-hydroxyethyl methacrylate by Pawlowska, Elzbieta, Poplawski, Tomasz, Ksiazek, Dominika, Szczepanska, Joanna, Blasiak, Janusz

“…Resin-based methacrylate materials are widely used in restorative dentistry. They are viscous substances that are converted into solid material via…”
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BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability by SLUPIANEK, Artur, POPLAWSKI, Tomasz, JOZWIAKOWSKI, Stanislaw K, CRAMER, Kimberly, PYTEL, Dariusz, STOCZYNSKA, Ewelina, NOWICKI, Michal O, BLASIAK, Janusz, SKORSKI, Tomasz

“…BCR/ABL-transformed chronic myeloid leukemia (CML) cells accumulate numerous DNA double-strand breaks (DSB) induced by reactive oxygen species (ROS) and…”
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BET Proteins as Attractive Targets for Cancer Therapeutics by Sarnik, Joanna, Popławski, Tomasz, Tokarz, Paulina

“…Transcriptional dysregulation is a hallmark of cancer and can be an essential driver of cancer initiation and progression. Loss of transcriptional control can…”
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