Search Results - "Pop, Laura Ancuta"
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Next Generation Sequencing Technology in Lung Cancer Diagnosis
Published in Biology (Basel, Switzerland) (03-09-2021)“…Lung cancer is still one of the most commonly diagnosed cancers, and one of the deadliest. The high death rate is mainly due to the late stage of diagnosis and…”
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Influenza A, Influenza B, and SARS-CoV-2 Similarities and Differences – A Focus on Diagnosis
Published in Frontiers in microbiology (20-06-2022)“…In late December 2019, the first cases of viral pneumonia caused by an unidentified pathogen were reported in China. Two years later, SARS-CoV-2 was…”
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3
The new era of nanotechnology, an alternative to change cancer treatment
Published in Drug design, development and therapy (01-01-2017)“…In the last few years, nanostructures have gained considerable interest for the safe delivery of therapeutic agents. Several therapeutic approaches have been…”
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Aberrant miRNAs expressed in HER-2 negative breast cancers patient
Published in Journal of experimental & clinical cancer research (20-10-2018)“…Breast cancer is a highly heterogeneous pathology, exhibiting a number of subtypes commonly associated with a poor outcome. Due to their high stability,…”
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5
Discovering the Biological Significance and Therapeutic Potential of miR-29b-3p in Triple-Negative Breast Cancer
Published in International journal of molecular sciences (01-03-2023)“…The lack of estrogen or progesterone receptors and absence of amplification/overexpression in triple-negative breast cancer (TNBC) restricts therapeutic…”
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New perspectives in triple-negative breast cancer therapy based on treatments with TGFβ1 siRNA and doxorubicin
Published in Molecular and cellular biochemistry (01-12-2020)“…Triple-negative breast cancer (TNBC), which accounts for 10–20% of all breast cancers, has the worst prognosis. Although chemotherapy treatment is a standard…”
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Exosome-Carried microRNA-375 Inhibits Cell Progression and Dissemination via Bcl-2 Blocking in Colon Cancer
Published in Journal of gastrointestinal and liver diseases : JGLD (01-12-2015)“…Worldwide, colorectal cancer (CRC) is the third most common cancer in men and second in women. The aim of the current study was to identify whether the miR-375…”
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8
Critical Analysis of Genome-Wide Association Studies: Triple Negative Breast Cancer Quae Exempli Causa
Published in International journal of molecular sciences (14-08-2020)“…Genome-wide association studies (GWAS) are useful in assessing and analyzing either differences or variations in DNA sequences across the human genome to…”
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New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells
Published in Journal of experimental & clinical cancer research (13-11-2020)“…Triple negative breast cancer (TNBC) is a heterogeneous disease with aggressive behavior and an unfavorable prognosis rate. Due to the lack of surface…”
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10
New Insights in Gene Expression Alteration as Effect of Paclitaxel Drug Resistance in Triple Negative Breast Cancer Cells
Published in Cellular physiology and biochemistry (04-07-2020)“…Triple negative breast cancer (TNBC) is a highly aggressive form of cancer which lacks targeted therapy options. Thus, TNBC patients have poor outcomes and a…”
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11
HLA Genotyping using Next Generation Sequencing
Published in Revue roumaine de médecine interne (1990) (01-06-2016)“…From an oncological perspective, the second most common malignancies in children are brain tumors. Despite the recent therapeutic breakthroughs in this field,…”
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Arsenic Methyltransferase and Apolipoprotein E Polymorphism in Pregnant Women Exposed to Inorganic Arsenic in Drinking Water in Western Romania
Published in International journal of molecular sciences (15-03-2024)“…Previous studies have shown that inorganic arsenic (iAs) exposure may be associated with genotoxic and cytotoxic effects. The aim of this study was to evaluate…”
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The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression
Published in Cell death & disease (19-01-2018)“…EMT represents the dominant program within advanced stages of colon cancer, where cells acquire migratory characteristics in order to invade secondary tissues…”
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Connecting the dots between different networks: miRNAs associated with bladder cancer risk and progression
Published in Journal of experimental & clinical cancer research (29-10-2019)“…Bladder cancer (BC) is a common urothelial malignancy, characterized by a high recurrence rate. The biology of bladder cancer is complex and needs to be…”
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Beyond Conventional: The New Horizon of Anti-Angiogenic microRNAs in Non-Small Cell Lung Cancer Therapy
Published in International journal of molecular sciences (27-10-2020)“…GLOBOCAN 2018 identified lung cancer as the leading oncological pathology in terms of incidence and mortality rates. Angiogenesis is a key adaptive mechanism…”
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Alteration of Gene and miRNA Expression in Cervical Intraepithelial Neoplasia and Cervical Cancer
Published in International journal of molecular sciences (27-05-2022)“…: Cervical cancer is one of the most common malignancies in women in terms of prevalence and mortality. Cervical cancer has some particularities that…”
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Dysregulation of miR-21-5p, miR-93-5p, miR-200c-3p and miR-205-5p in Oral Squamous Cell Carcinoma: A Potential Biomarkers Panel?
Published in Current issues in molecular biology (16-04-2022)“…Oral squamous cell carcinoma (OSCC) is considered the sixth most common cancer worldwide. To reduce the high mortality of the disease, sensitive and specific…”
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Genetic alterations in sporadic triple negative breast cancer
Published in Breast (Edinburgh) (01-04-2018)“…Recent studies have aimed to identify gene mutation profiles to explain the cause of TNBC therapy limitations. The purpose of our study was to use Next…”
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Identification of a miRNA Panel with a Potential Determinant Role in Patients Suffering from Periodontitis
Published in Current issues in molecular biology (01-03-2023)“…In recent years, the role of microRNA (miRNA) in post-transcriptional gene regulation has advanced and supports strong evidence related to their important role…”
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Partnering bevacizumab with irinotecan as first line-therapy of metastatic colorectal cancer improves progression free survival-A retrospective analysis
Published in PloS one (28-04-2021)“…Colorectal cancer remains one of the most frequent malignancies (third place at both genders) worldwide in the last decade, owing to significant changes in…”
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