Search Results - "Poosala, Suresh"

AGEMAP: a gene expression database for aging in mice by Zahn, Jacob M, Poosala, Suresh, Owen, Art B, Ingram, Donald K, Lustig, Ana, Carter, Arnell, Weeraratna, Ashani T, Taub, Dennis D, Gorospe, Myriam, Mazan-Mamczarz, Krystyna, Lakatta, Edward G, Boheler, Kenneth R, Xu, Xiangru, Mattson, Mark P, Falco, Geppino, Ko, Minoru S H, Schlessinger, David, Firman, Jeffrey, Kummerfeld, Sarah K, Wood, 3rd, William H, Zonderman, Alan B, Kim, Stuart K, Becker, Kevin G

“…We present the AGEMAP (Atlas of Gene Expression in Mouse Aging Project) gene expression database, which is a resource that catalogs changes in gene expression…”
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Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction by Pearson, Kevin J, Lewis, Kaitlyn N, Price, Nathan L, Chang, Joy W, Perez, Evelyn, Cascajo, Maria Victoria, Tamashiro, Kellie L, Poosala, Suresh, Csiszar, Anna, Ungvari, Zoltan, Kensler, Thomas W, Yamamoto, Masayuki, Egan, Josephine M, Longo, Dan L, Ingram, Donald K, Navas, Placido, de Cabo, Rafael

“…Caloric restriction (CR) is the most potent intervention known to both protect against carcinogenesis and extend lifespan in laboratory animals. A variety of…”
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Chronic ingestion of 2-deoxy- d-glucose induces cardiac vacuolization and increases mortality in rats by Minor, Robin K., Smith, Daniel L., Sossong, Alex M., Kaushik, Susmita, Poosala, Suresh, Spangler, Edward L., Roth, George S., Lane, Mark, Allison, David B., de Cabo, Rafael, Ingram, Donald K., Mattison, Julie A.

“…Calorie restriction (CR), the purposeful reduction of energy intake with maintenance of adequate micronutrient intake, is well known to extend the lifespan of…”
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Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke by Mattson, Mark P, Arumugam, Thiruma V, Chan, Sic L, Jo, Dong-Gyu, Yilmaz, Gokhan, Tang, Sung-Chun, Cheng, Aiwu, Gleichmann, Marc, Okun, Eitan, Dixit, Vishwa D, Chigurupati, Srinivasulu, Mughal, Mohamed R, Ouyang, Xin, Miele, Lucio, Magnus, Tim, Poosala, Suresh, Granger, D Neil

“…Mice transgenic for antisense Notch and normal mice treated with inhibitors of the Notch-activating enzyme γ-secretase showed reduced damage to brain cells and…”
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Involvement of notch signaling in wound healing by Chigurupati, Srinivasulu, Arumugam, Thiruma V, Son, Tae Gen, Lathia, Justin D, Jameel, Shafaq, Mughal, Mohamed R, Tang, Sung-Chun, Jo, Dong-Gyu, Camandola, Simonetta, Giunta, Marialuisa, Rakova, Irina, McDonnell, Nazli, Miele, Lucio, Mattson, Mark P, Poosala, Suresh

“…The Notch signaling pathway is critically involved in cell fate decisions during development of many tissues and organs. In the present study we employed in…”
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Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender by Xu, Xiangru, Zhan, Ming, Duan, Wenzhen, Prabhu, Vinayakumar, Brenneman, Randall, Wood, William, Firman, Jeff, Li, Huai, Zhang, Peisu, Ibe, Carol, Zonderman, Alan B, Longo, Dan L, Poosala, Suresh, Becker, Kevin G, Mattson, Mark P

“…The structural and functional complexity of the mammalian central nervous system (CNS) is organized and modified by complicated molecular signaling processes…”
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Effects of aging and calorie restriction on the global gene expression profiles of mouse testis and ovary by Sharov, Alexei A, Falco, Geppino, Piao, Yulan, Poosala, Suresh, Becker, Kevin G, Zonderman, Alan B, Longo, Dan L, Schlessinger, David, Ko, Minoru Sh

“…The aging of reproductive organs is not only a major social issue, but of special interest in aging research. A long-standing view of 'immortal germ line…”
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A synthetic uric acid analog accelerates cutaneous wound healing in mice by Chigurupati, Srinivasulu, Mughal, Mohamed R, Chan, Sic L, Arumugam, Thiruma V, Baharani, Akanksha, Tang, Sung-Chun, Yu, Qian-Sheng, Holloway, Harold W, Wheeler, Ross, Poosala, Suresh, Greig, Nigel H, Mattson, Mark P

“…Wound healing is a complex process involving intrinsic dermal and epidermal cells, and infiltrating macrophages and leukocytes. Excessive oxidative stress and…”
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Red cell interactions with amyloid-β1–40 fibrils in a murine model by Ravi, Luke B., Poosala, Suresh, Ahn, Dongchoon, Chrest, Francis J., Spangler, Edward L., Jayakumar, Rajadas, Nagababu, Enika, Mohanty, Joy G., Talan, Mark, Ingram, Donald K., Rifkind, Joseph M.

“…Vascular amyloidosis in Alzheimer's disease (AD) results in the exposure of red blood cells to β-amyloid fibrils (Aβ). The potential in vivo ramifications of…”
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The Capability Maturity Model as a Measure of Culture of Care in Laboratory Animal Science by Amarasekara, Dulshara Sachini, Rathnadiwakara, Hasanthi, Ratnayake, Kalpani, Gunatilake, Mangala, Singh, Vijay Pal, Poosala, Suresh

“…Culture of care in Laboratory Animal Science (LAS) refers to a commitment toward improving animal welfare, scientific quality, staff wellbeing, and…”
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Resveratrol improves health and survival of mice on a high-calorie diet by Baur, J.A, Pearson, K.J, Price, N.L, Jamieson, H.A, Lerin, C, Kalra, A, Prabhu, V.V, Allard, J.S, Lopez-Lluch, G, Lewis, K

“…Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila…”
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Comparative evaluation of several techniques for purification of Cryptosporidium parvum oocysts from rat feces by Suresh, P. (St. Jude Children's Research Hospital, Memphis, TN.), Rehg, J.E

“…Three methods of isolating Cryptosporidium parvum oocysts from rat feces were evaluated. Oocyts were initially isolated by sucrose density gradient…”
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Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Third International Conference on 3Rs Research and Progress, Vishakhapatnam, 2022 by Naik, Nikita Narayan, Vadloori, Bharadwaja, Poosala, Suresh, Srivastava, Pratima, Coecke, Sandra, Smith, Adrian, Akhtar, Aysha, Roper, Clive, Radhakrishnan, Sridhar, Bhyravbhatla, Balaji, Damle, Madhujit, Pulla, Venkat Koushik, Hackethal, Johannes, Horland, Reyk, Li, Albert P., Pati, Falguni, Singh, Manu Smriti, Occhetta, Paola, Bisht, Rohit, Dandekar, Prajakta, Bhagavatula, Krishna, Pajkrt, Dasja, Johnson, Michael, Weber, Tilo, Huang, John, Hysenaj, Lisiena, Mallar, Banerjee, Ramray, Bhat, Dixit, Santosh, Joshi, Shreekanth, Kulkarni, Mandar

“…Animal experimentation has been integral to drug discovery and development and safety assessment for many years, since it provides insights into the mechanisms…”
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Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Second International Conference on 3Rs Research and Progress, Hyderabad, 2021 by Sonawane, Akshay, Vadloori, Bharadwaja, Poosala, Suresh, Kandarova, Helena, Kulkarni, Mandar, Olayanju, Adedamola, Dey, Tuli, Saxena, Uday, Smirnova, Lena, Kanda, Yasunari, Reddy, Jaganmohan, Dravida, Subhadra, Biswas, Saikat, Vinken, Mathieu, Gettayacamin, Montip, Ahluwalia, Arti, Mondini, Franco, Bhattacharya, Somshuvra, Kulkarni, Pushkar, Jacobsen, Kirsten Rosenmay, Vangala, Subrahmanyam, Millás, Ana Luiza

“…The fact that animal models fail to replicate human disease faithfully is now being widely accepted by researchers across the globe. As a result, they are…”
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Laws, Regulations, Guidelines and Standards for Animal Care and Use for Scientific Purposes in the Countries of Singapore, Thailand, Indonesia, Malaysia, and India by Retnam, Leslie, Chatikavanij, Pradon, Kunjara, Pattamarat, Paramastri, Yasmina A, Goh, Yong Meng, Hussein, Fuzina Nor, Mutalib, Abdul Rahim, Poosala, Suresh

“…The laws, regulations, guidelines, and standards on animal care and use for scientific purposes in the countries of Singapore, Thailand, Indonesia, and…”
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Improvement of Vivarium Biodecontamination through Data-acquisition Systems and Automation by Devan, Shakthi RK, Vasu, Suresh, Mallikarjuna, Yogesha, Ponraj, Ramkumar, Kamath, Gireesh, Poosala, Suresh

“…Biodecontamination is important for eliminating pathogens at research animal facilities, thereby preventing contamination within barrier systems. We enhanced…”
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Age-Related Changes of Claudin Expression in Mouse Liver, Kidney, and Pancreas by D’Souza, Theresa, Sherman-Baust, Cheryl A., Poosala, Suresh, Mullin, James M., Morin, Patrice J.

“…Tight junctions (TJs) play crucial roles in tissue homeostasis and inflammation through their roles in the control of paracellular transport and barrier…”
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EFFECTS OF AGING AND CALORIC RESTRICTION ON THE GLOBAL GENE EXPRESSION PROFILES OF TESTIS AND OVARY by Falco, Geppino, Sharov, Alexei, Piao, Yulan, Poosala, Suresh, Becker, Kevin, Zonderman, Alan, Longo, Dan, Schlessinger, David, Ko, Minoru

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Transcriptome analysis of age-, gender- and diet-associated changes in murine thymus by Lustig, Ana, Weeraratna, Ashani T., Wood, William W., Teichberg, Diane, Bertak, Dorothy, Carter, Arnell, Poosala, Suresh, Firman, Jeffrey, Becker, Kevin G., Zonderman, Alan B., Longo, Dan L., Taub, Dennis D.

“…The loss of thymic function with age may be due to diminished numbers of T-cell progenitors and the loss of critical mediators within the thymic…”
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Validated alternatives: is immediate implementation required? IACUC must review by Bell, Jeffrey B, Poosala, Suresh, Smith, Rebekah

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