Search Results - "Poortvliet, Rosalinde K. E"
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Potentially inappropriate medication and attitudes of older adults towards deprescribing
Published in PloS one (26-10-2020)“…Multimorbidity and polypharmacy are current challenges when caring for the older population. Both have led to an increase of potentially inappropriate…”
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What do older adults with multimorbidity and polypharmacy think about deprescribing? The LESS study - a primary care-based survey
Published in BMC geriatrics (31-10-2020)“…Multimorbidity and polypharmacy are very common in older adults in primary care. Ideally, general practitioners (GPs), should regularly review medication lists…”
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High Blood Pressure and Resilience to Physical and Cognitive Decline in the Oldest Old: The Leiden 85-Plus Study
Published in Journal of the American Geriatrics Society (JAGS) (01-11-2012)“…Objectives To evaluate the association between various blood pressure (BP) measures at age 85 and future decline in physical and cognitive function the oldest…”
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Deprescribing preventive cardiovascular medication in patients with predicted low cardiovascular disease risk in general practice - the ECSTATIC study: a cluster randomised non-inferiority trial
Published in BMC medicine (11-01-2018)“…The use of cardiovascular medication for the primary prevention of cardiovascular disease (CVD) is potentially inappropriate when potential risks outweigh the…”
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Correction: Statin Use and Self-Reported Hindering Muscle Complaints in Older Persons: A Population Based Study
Published in PloS one (22-01-2021)“…[This corrects the article DOI: 10.1371/journal.pone.0166857.]…”
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Assessment of the appropriateness of cardiovascular preventive medication in older people: using the RAND/UCLA Appropriateness Method
Published in BMC geriatrics (05-05-2022)“…In clinical practice and science, there is debate for which older adults the benefits of cardiovascular preventive medications (CPM) still outweigh the risks…”
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Understanding older patients’ willingness to have medications deprescribed in primary care: a protocol for a cross-sectional survey study in nine European countries
Published in BMC geriatrics (30-11-2022)“…Abstract Introduction To reduce inappropriate polypharmacy, deprescribing should be part of patients’ regular care. Yet deprescribing is difficult to…”
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Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)
Published in PloS one (20-12-2012)“…Variability in blood pressure predicts cardiovascular disease in young- and middle-aged subjects, but relevant data for older individuals are sparse. We…”
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Statin Use and Self-Reported Hindering Muscle Complaints in Older Persons: A Population Based Study
Published in PloS one (02-12-2016)“…Statins are widely used by older persons in primary and secondary prevention of cardiovascular disease. Although serious adverse events are rare, many statin…”
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The effect of ultraviolet irradiation compared to oral vitamin D supplementation on blood pressure of nursing home residents with dementia
Published in BMC geriatrics (19-10-2021)“…Abstract Background Observational studies have reported an inverse association between ultraviolet (UV) radiation and hypertension. The aim of this study was…”
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Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism
Published in JAMA : the journal of the American Medical Association (26-11-2019)“…IMPORTANCE: It is unclear whether levothyroxine treatment provides clinically important benefits in adults aged 80 years and older with subclinical…”
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Association of low blood pressure and falls: An analysis of data from the Leiden 85-plus Study
Published in PloS one (20-12-2023)“…Falls and consequent injuries are prevalent in older adults. In this group, half of injury-related hospitalizations are associated with falls and the rate of…”
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N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk
Published in Annals of neurology (01-08-2014)“…Objective Elevated levels of N‐terminal pro–brain natriuretic peptide (NT‐proBNP) are associated with cognitive impairment, which might be explained by…”
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Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines
Published in Journal of the American Geriatrics Society (JAGS) (01-02-2020)“…OBJECTIVES As a person's age increases and his/her health status declines, new challenges arise that may lead physicians to consider deprescribing statins. We…”
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Effects of discontinuation of levothyroxine treatment in older adults: protocol for a self-controlled trial
Published in BMJ open (25-04-2023)“…BackgroundMany older persons use the thyroid hormone levothyroxine which is often continued for life. Scientifically, there is much uncertainty whether simple…”
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Managing hypertension in frail oldest-old - the role of guideline use by general practitioners from 29 countries
Published in PloS one (10-07-2020)“…Investigates guideline use amongst general practitioners (GP) from 26 European countries and from Brazil, Israel and New Zealand, regarding best management of…”
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Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials
Published in Frontiers in endocrinology (Lausanne) (20-05-2021)“…The cardiovascular effects of treating older adults with subclinical hypothyroidism (SCH) are uncertain. Although concerns have been raised regarding a…”
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Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial
Published in JAMA network open (01-02-2021)“…Previous trials on the effect of levothyroxine on depressive symptom scores in patients with subclinical hypothyroidism were limited by small sample sizes (N =…”
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Biomarkers versus traditional risk factors to predict cardiovascular events in very old adults: cross-validated prospective cohort study
Published in BMJ open (28-06-2020)“…ObjectivesTo test new cardiovascular (CV) risk models in very old adults with and without a history of CV disease (CVD), based on traditional risk factors and…”
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A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations
Published in European thyroid journal (01-06-2024)“…Subclinical thyroid diseases are often the subject of debate concerning their clinical significance, the appropriateness of diagnostic testing, and possible…”
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