Search Results - "Poonam, Patil"
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Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases
Published in Current drug targets (01-01-2023)“…Pyroptosis has become a noteworthy area of focus in recent years due to its association with inflammatory diseases. Pyroptosis is a type of programmed cell…”
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Immunomodulatory effect of 1, 25 dihydroxy vitamin D3 on the expression of RNA sensing pattern recognition receptor genes and cytokine response in dengue virus infected U937-DC-SIGN cells and THP-1 macrophages
Published in International immunopharmacology (01-09-2018)“…Dengue virus (DENV) infections are straining public health systems worldwide. Vitamin D, a secosteroid hormone, is currently being investigated for its…”
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Immunomodulatory effect of 1, 25 dihydroxy vitamin D 3 on the expression of RNA sensing pattern recognition receptor genes and cytokine response in dengue virus infected U937-DC-SIGN cells and THP-1 macrophages
Published in International immunopharmacology (01-09-2018)“…Dengue virus (DENV) infections are straining public health systems worldwide. Vitamin D, a secosteroid hormone, is currently being investigated for its…”
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In Vitro Antiviral Activity of α-Mangostin against Dengue Virus Serotype-2 (DENV-2)
Published in Molecules (Basel, Switzerland) (19-05-2021)“…Dengue virus (DENV), a member of the family Flaviviridae, is a threat for global health as it infects more than 100 million people yearly. Approved antiviral…”
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Effect of Cationic Lipid Nanoparticle Loaded siRNA with Stearylamine against Chikungunya Virus
Published in Molecules (Basel, Switzerland) (09-02-2022)“…Chikungunya is an infectious disease caused by mosquito-transmitted chikungunya virus (CHIKV). It was reported that NS1 and E2 siRNAs administration…”
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In vitro and in vivo studies reveal α-Mangostin, a xanthonoid from Garcinia mangostana, as a promising natural antiviral compound against chikungunya virus
Published in Virology journal (28-02-2021)“…Chikungunya virus (CHIKV), a serious health problem in several tropical countries, is the causative agent of chikungunya fever. Approved antiviral therapies or…”
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Anti-Dengue Activity of Lipophilic Fraction of Ocimum basilicum L. Stem
Published in Molecules (Basel, Switzerland) (02-02-2023)“…L. is used to cure many types of fever in traditional medicine. This study aims to explore the antiviral activity of the lipophilic fraction of the stem of…”
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Molecular Testing in Stage 4 Stomach Cancer in India: A Single-Centre Experience
Published in Curēus (Palo Alto, CA) (25-11-2023)“…IntroductionAdvanced gastric cancer (GC) has a very poor prognosis, and chemotherapy has been the standard of care. The use of immunotherapy or targeted…”
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Studies on the antiviral activity of chebulinic acid against dengue and chikungunya viruses and in silico investigation of its mechanism of inhibition
Published in Scientific reports (21-06-2022)“…Chebulinic acid (CA), originally isolated from the flower extract of the plant Terminalia chebula , has been shown to inhibit infection of herpes simplex…”
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Drug repurposing approach against chikungunya virus: an in vitro and in silico study
Published in Frontiers in cellular and infection microbiology (27-04-2023)“…The chikungunya virus (CHIKV) is an alphavirus transmitted by . There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing…”
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A Transcriptomics-Based Bioinformatics Approach for Identification and In Vitro Screening of FDA-Approved Drugs for Repurposing against Dengue Virus-2
Published in Viruses (29-09-2022)“…The rising incidence of dengue virus (DENV) infections in the tropical and sub-tropical regions of the world emphasizes the need to identify effective…”
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Effect of full-length and truncated variants of LL-37 on dengue virus infection and immunomodulatory effects of LL-37 in dengue virus infected U937-DC-SIGN cells
Published in International journal of peptide research and therapeutics (01-03-2020)“…LL-37 is an antiviral and an immunomodulatory antimicrobial peptide present in humans. The present study investigated the inhibitory effect of LL-37 and its…”
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In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses
Published in Frontiers in cellular and infection microbiology (07-04-2022)“…Dengue and chikungunya are two important mosquito-borne infections which are known to occur extensively in tropical and subtropical areas. Presently, there is…”
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Corrigendum: Drug repurposing approach against chikungunya virus: an in vitro and in silico study
Published in Frontiers in cellular and infection microbiology (23-06-2023)“…[This corrects the article DOI: 10.3389/fcimb.2023.1132538.]…”
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Targeted in vitro gene silencing of E2 and nsP1 genes of chikungunya virus by biocompatible zeolitic imidazolate framework
Published in Frontiers in bioengineering and biotechnology (14-12-2022)“…Chikungunya fever caused by the mosquito-transmitted chikungunya virus (CHIKV) is a major public health concern in tropical, sub-tropical and temperate…”
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Expert Consensus on Effective Management of Chemotherapy-Induced Nausea and Vomiting: An Indian Perspective
Published in Frontiers in oncology (27-03-2020)“…Chemotherapy-induced nausea and vomiting (CINV) is one of the most common and feared side effects in cancer patients undergoing chemotherapy. Scientific…”
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Real-World Experience with Nivolumab in Metastatic Renal Cell Carcinoma Patients Who Have Progressed on Prior Therapies: A Single-Center Study from India
Published in South Asian journal of cancer (01-04-2022)“…Introduction Nivolumab monotherapy is approved for the treatment of metastatic renal cell carcinoma (mRCC) patients who have progressed on prior therapies…”
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Practical Consensus Guidelines on the Use of Cetuximab in Head and Neck Squamous Cell Carcinoma (HNSCC)
Published in South Asian journal of cancer (16-10-2024)“…Head and neck squamous cell carcinoma (HNSCC) is the most common malignancy group in India and several other low- and middle-income countries. Currently,…”
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An Overview of the Impact of Body Mass Index on Pathological Complete Response Following Neoadjuvant Chemotherapy in Operable Breast Cancer in a Tertiary Care Centre in South India
Published in European journal of breast health (01-07-2022)“…ObjectiveThe incidence of female breast cancer in the world is 11.7% with a mortality rate of 6.9%. According to Globocon 2020, breast cancer is the most…”
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Reactions of ketene dithioacetal for a new versatile synthesis of 4,5-substituted 3-aminothiophene-2-carboxylate derivatives
Published in Journal of sulfur chemistry (03-07-2016)“…Poly substituted 3-aminothiophenes were successfully synthesized in good yields by using a one-pot protocol via ketene S,S-acetal as an intermediate in basic…”
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