Search Results - "Poon, Leo L. M."

Emergence of a novel human coronavirus threatening human health by Poon, Leo L. M., Peiris, Malik

“…In late December 2019, a cluster of patients with ‘atypical pneumonia’ of unknown etiology was reported in Wuhan, China. A novel human coronavirus, now…”
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Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination by Cheng, Samuel M. S., Mok, Chris Ka Pun, Leung, Yonna W. Y., Ng, Susanna S., Chan, Karl C. K., Ko, Fanny W., Chen, Chunke, Yiu, Karen, Lam, Bosco H. S., Lau, Eric H. Y., Chan, Ken K. P., Luk, Leo L. H., Li, John K. C., Tsang, Leo C. H., Poon, Leo L. M., Hui, David S. C., Peiris, Malik

“…The Omicron variant is rapidly becoming the dominant SARS-CoV-2 virus circulating globally. It is important to define reductions in virus neutralizing activity…”
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Neutralizing antibody titres in SARS-CoV-2 infections by Lau, Eric H. Y., Tsang, Owen T. Y., Hui, David S. C., Kwan, Mike Y. W., Chan, Wai-hung, Chiu, Susan S., Ko, Ronald L. W., Chan, Kin H., Cheng, Samuel M. S., Perera, Ranawaka A. P. M., Cowling, Benjamin J., Poon, Leo L. M., Peiris, Malik

“…The SARS-CoV-2 pandemic poses the greatest global public health challenge in a century. Neutralizing antibody is a correlate of protection and data on kinetics…”
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ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection by Hachim, Asmaa, Kavian, Niloufar, Cohen, Carolyn A., Chin, Alex W. H., Chu, Daniel K. W., Mok, Chris K. P., Tsang, Owen T. Y., Yeung, Yiu Cheong, Perera, Ranawaka A. P. M., Poon, Leo L. M., Peiris, J. S. Malik, Valkenburg, Sophie A.

“…The SARS-CoV-2 virus emerged in December 2019 and has caused a worldwide pandemic due to the lack of any pre-existing immunity. Accurate serology testing is…”
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Highly Conserved Protective Epitopes on Influenza B Viruses by Dreyfus, Cyrille, Laursen, Nick S., Kwaks, Ted, Zuijdgeest, David, Khayat, Reza, Ekiert, Damian C., Lee, Jeong Hyun, Metlagel, Zoltan, Bujny, Miriam V., Jongeneelen, Mandy, van der Vlugt, Remko, Lamrani, Mohammed, Korse, Hans J. W. M., Geelen, Eric, Sahin, Özcan, Sieuwerts, Martijn, Brakenhoff, Just P. J., Vogels, Ronald, Li, Olive T. W., Poon, Leo L. M., Peiris, Malik, Koudstaal, Wouter, Ward, Andrew B., Wilson, Ian A., Goudsmit, Jaap, Friesen, Robert H. E.

“…Identification of broadly neutralizing antibodies against influenza A viruses has raised hopes for the development of monoclonal antibody—based immunotherapy…”
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A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses by Ekiert, Damian C., Friesen, Robert H. E., Bhabha, Gira, Kwaks, Ted, Jongeneelen, Mandy, Yu, Wenli, Ophorst, Carla, Cox, Freek, Korse, Hans J.W.M., Brandenburg, Boerries, Vogels, Ronald, Brakenhoff, Just P.J., Kompier, Ronald, Koldijk, Martin H., Cornelissen, Lisette A.H.M., Poon, Leo L. M., Peiris, Malik, Koudstaal, Wouter, Wilson, Ian A., Goudsmit, Jaap

“…Current flu vaccines provide only limited coverage against seasonal strains of influenza viruses. The identification of V H 1-69 antibodies that broadly…”
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Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin by Laursen, Nick S, Friesen, Robert H E, Zhu, Xueyong, Jongeneelen, Mandy, Blokland, Sven, Vermond, Jan, van Eijgen, Alida, Tang, Chan, van Diepen, Harry, Obmolova, Galina, van der Neut Kolfschoten, Marijn, Zuijdgeest, David, Straetemans, Roel, Hoffman, Ryan M B, Nieusma, Travis, Pallesen, Jesper, Turner, Hannah L, Bernard, Steffen M, Ward, Andrew B, Luo, Jinquan, Poon, Leo L M, Tretiakova, Anna P, Wilson, James M, Limberis, Maria P, Vogels, Ronald, Brandenburg, Boerries, Kolkman, Joost A, Wilson, Ian A

“…Broadly neutralizing antibodies against highly variable pathogens have stimulated the design of vaccines and therapeutics. We report the use of diverse camelid…”
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SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infection by Cohen, Carolyn A., Li, Athena P. Y., Hachim, Asmaa, Hui, David S. C., Kwan, Mike Y. W., Tsang, Owen T. Y., Chiu, Susan S., Chan, Wai Hung, Yau, Yat Sun, Kavian, Niloufar, Ma, Fionn N. L., Lau, Eric H. Y., Cheng, Samuel M. S., Poon, Leo L. M., Peiris, Malik, Valkenburg, Sophie A.

“…SARS-CoV-2 infection of children leads to a mild illness and the immunological differences with adults are unclear. Here, we report SARS-CoV-2 specific T cell…”
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Reply to: Population genetic considerations regarding the interpretation of within-patient SARS-CoV-2 polymorphism data by Nelson, Chase W., Poon, Leo L. M., Gu, Haogao

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SARS-CoV-2 virus transfers to skin through contact with contaminated solids by Behzadinasab, Saeed, Chin, Alex W. H., Hosseini, Mohsen, Poon, Leo L. M., Ducker, William A.

“…Transfer of SARS-CoV-2 from solids to fingers is one step in infection via contaminated solids, and the possibility of infection from this route has driven…”
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Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells by Throsby, Mark, van den Brink, Edward, Jongeneelen, Mandy, Poon, Leo L M, Alard, Philippe, Cornelissen, Lisette, Bakker, Arjen, Cox, Freek, van Deventer, Els, Guan, Yi, Cinatl, Jindrich, ter Meulen, Jan, Lasters, Ignace, Carsetti, Rita, Peiris, Malik, de Kruif, John, Goudsmit, Jaap

“…The hemagglutinin (HA) glycoprotein is the principal target of protective humoral immune responses to influenza virus infections but such antibody responses…”
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Seasonal antigenic prediction of influenza A H3N2 using machine learning by Shah, Syed Awais W., Palomar, Daniel P., Barr, Ian, Poon, Leo L. M., Quadeer, Ahmed Abdul, McKay, Matthew R.

“…Antigenic characterization of circulating influenza A virus (IAV) isolates is routinely assessed by using the hemagglutination inhibition (HI) assays for…”
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Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus by Wong, Emily H M, Smith, David K, Rabadan, Raul, Peiris, Malik, Poon, Leo L M

“…The influenza A virus is an important infectious cause of morbidity and mortality in humans and was responsible for 3 pandemics in the 20th century. As the…”
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Long-term evolution and transmission dynamics of swine influenza A virus by Vijaykrishna, Dhanasekaran, Smith, Gavin J. D., Pybus, Oliver G., Zhu, Huachen, Bhatt, Samir, Poon, Leo L. M., Riley, Steven, Bahl, Justin, Ma, Siu K., Cheung, Chung L., Perera, Ranawaka A. P. M., Chen, Honglin, Shortridge, Kennedy F., Webby, Richard J., Webster, Robert G., Guan, Yi, Peiris, J. S. Malik

“…Swine flu surveillance in pigs Pigs are recognized as important 'mixing vessels' in which influenza viruses can undergo reassortment, but despite the resulting…”
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Author Correction: Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children by Jia, Janice Z., Cohen, Carolyn A., Gu, Haogao, McLean, Milla R., Varadarajan, Raghavan, Bhandari, Nisha, Peiris, Malik, Leung, Gabriel M., Poon, Leo L. M., Tsang, Tim, Chung, Amy W., Cowling, Benjamin J., Leung, Nancy H. L., Valkenburg, Sophie A.

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The viruses of wild pigeon droppings by Phan, Tung Gia, Vo, Nguyen Phung, Boros, Ákos, Pankovics, Péter, Reuter, Gábor, Li, Olive T W, Wang, Chunling, Deng, Xutao, Poon, Leo L M, Delwart, Eric

“…Birds are frequent sources of emerging human infectious diseases. Viral particles were enriched from the feces of 51 wild urban pigeons (Columba livia) from…”
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Hemagglutinin–neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets by Yen, Hui-Ling, Liang, Chi-Hui, Wu, Chung-Yi, Forrest, Heather L, Ferguson, Angela, Choy, Ka-Tim, Jones, Jeremy, Wong, Diana Dik-Yan, Cheung, Peter Pak-Hang, Hsu, Che-Hsiung, Li, Olive T, Yuen, Kit M, Chan, Renee W. Y, Poon, Leo L. M, Chan, Michael C. W, Nicholls, John M, Krauss, Scott, Wong, Chi-Huey, Guan, Yi, Webster, Robert G, Webby, Richard J, Peiris, Malik

“…A novel reassortant derived from North American triple-reassortant (TRsw) and Eurasian swine (EAsw) influenza viruses acquired sustained human-to-human…”
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Viral load of SARS-CoV-2 in clinical samples by Pan, Yang, Zhang, Daitao, Yang, Peng, Poon, Leo L M, Wang, Quanyi

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SARS-CoV-2 accessory proteins reveal distinct serological signatures in children by Hachim, Asmaa, Gu, Haogao, Kavian, Otared, Mori, Masashi, Kwan, Mike Y. W., Chan, Wai Hung, Yau, Yat Sun, Chiu, Susan S., Tsang, Owen T. Y., Hui, David S. C., Mok, Chris K. P., Ma, Fionn N. L., Lau, Eric H. Y., Amarasinghe, Gaya K., Qavi, Abraham J., Cheng, Samuel M. S., Poon, Leo L. M., Peiris, J. S. Malik, Valkenburg, Sophie A., Kavian, Niloufar

“…The antibody response magnitude and kinetics may impact clinical severity, serological diagnosis and long-term protection of COVID-19, which may play a role in…”
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Characterization and Complete Genome Sequence of a Novel Coronavirus, Coronavirus HKU1, from Patients with Pneumonia by WOO, Patrick C. Y, LAU, Susanna K. P, POON, Leo L. M, WONG, Samson S. Y, YI GUAN, PEIRIS, J. S, YUEN, Kwok-Yung, CHU, Chung-Ming, CHAN, Kwok-Hung, TSOI, Hoi-Wah, YI HUANG, WONG, Beatrice H. L, POON, Rosana W. S, CAI, James J, LUK, Wei-Kwang

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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