Search Results - "Poon, Leo"

Emergence of a novel human coronavirus threatening human health by Poon, Leo L. M., Peiris, Malik

“…In late December 2019, a cluster of patients with ‘atypical pneumonia’ of unknown etiology was reported in Wuhan, China. A novel human coronavirus, now…”
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Viral load of SARS-CoV-2 in clinical samples by Pan, Yang, Zhang, Daitao, Yang, Peng, Poon, Leo L M, Wang, Quanyi

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Pathogenesis and transmission of SARS-CoV-2 in golden hamsters by Sia, Sin Fun, Yan, Li-Meng, Chin, Alex W. H., Fung, Kevin, Choy, Ka-Tim, Wong, Alvina Y. L., Kaewpreedee, Prathanporn, Perera, Ranawaka A. P. M., Poon, Leo L. M., Nicholls, John M., Peiris, Malik, Yen, Hui-Ling

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus with high nucleotide identity to SARS-CoV and to SARS-related coronaviruses…”
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Cupric Oxide Coating That Rapidly Reduces Infection by SARS-CoV‑2 via Solids by Hosseini, Mohsen, Chin, Alex W. H, Behzadinasab, Saeed, Poon, Leo L. M, Ducker, William A

“…The ongoing COVID-19 pandemic has created a need for coatings that reduce infection from SARS-CoV-2 via surfaces. Such a coating could be used on common touch…”
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Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination by Cheng, Samuel M. S., Mok, Chris Ka Pun, Leung, Yonna W. Y., Ng, Susanna S., Chan, Karl C. K., Ko, Fanny W., Chen, Chunke, Yiu, Karen, Lam, Bosco H. S., Lau, Eric H. Y., Chan, Ken K. P., Luk, Leo L. H., Li, John K. C., Tsang, Leo C. H., Poon, Leo L. M., Hui, David S. C., Peiris, Malik

“…The Omicron variant is rapidly becoming the dominant SARS-CoV-2 virus circulating globally. It is important to define reductions in virus neutralizing activity…”
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SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease by Perera, Ranawaka A P M, Tso, Eugene, Tsang, Owen T Y, Tsang, Dominic N C, Fung, Kitty, Leung, Yonna W Y, Chin, Alex W H, Chu, Daniel K W, Cheng, Samuel M S, Poon, Leo L M, Chuang, Vivien W M, Peiris, Malik

“…We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory…”
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Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia by Chu, Daniel K W, Pan, Yang, Cheng, Samuel M S, Hui, Kenrie P Y, Krishnan, Pavithra, Liu, Yingzhi, Ng, Daisy Y M, Wan, Carrie K C, Yang, Peng, Wang, Quanyi, Peiris, Malik, Poon, Leo L M

“…Abstract Background A novel coronavirus of zoonotic origin (2019-nCoV) has recently been identified in patients with acute respiratory disease. This virus is…”
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Neutralizing antibody titres in SARS-CoV-2 infections by Lau, Eric H. Y., Tsang, Owen T. Y., Hui, David S. C., Kwan, Mike Y. W., Chan, Wai-hung, Chiu, Susan S., Ko, Ronald L. W., Chan, Kin H., Cheng, Samuel M. S., Perera, Ranawaka A. P. M., Cowling, Benjamin J., Poon, Leo L. M., Peiris, Malik

“…The SARS-CoV-2 pandemic poses the greatest global public health challenge in a century. Neutralizing antibody is a correlate of protection and data on kinetics…”
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Probable Transmission of SARS-CoV-2 Omicron Variant in Quarantine Hotel, Hong Kong, China, November 2021 by Gu, Haogao, Krishnan, Pavithra, Ng, Daisy Y M, Chang, Lydia D J, Liu, Gigi Y Z, Cheng, Samuel S M, Hui, Mani M Y, Fan, Mathew C Y, Wan, Jacob H L, Lau, Leo H K, Cowling, Benjamin J, Peiris, Malik, Poon, Leo L M

“…We report detection of severe acute respiratory syndrome coronavirus 2 Omicron variant (B.1.1.529) in an asymptomatic, fully vaccinated traveler in a…”
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Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus by Wong, Emily H M, Smith, David K, Rabadan, Raul, Peiris, Malik, Poon, Leo L M

“…The influenza A virus is an important infectious cause of morbidity and mortality in humans and was responsible for 3 pandemics in the 20th century. As the…”
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Highly Conserved Protective Epitopes on Influenza B Viruses by Dreyfus, Cyrille, Laursen, Nick S., Kwaks, Ted, Zuijdgeest, David, Khayat, Reza, Ekiert, Damian C., Lee, Jeong Hyun, Metlagel, Zoltan, Bujny, Miriam V., Jongeneelen, Mandy, van der Vlugt, Remko, Lamrani, Mohammed, Korse, Hans J. W. M., Geelen, Eric, Sahin, Özcan, Sieuwerts, Martijn, Brakenhoff, Just P. J., Vogels, Ronald, Li, Olive T. W., Poon, Leo L. M., Peiris, Malik, Koudstaal, Wouter, Ward, Andrew B., Wilson, Ian A., Goudsmit, Jaap, Friesen, Robert H. E.

“…Identification of broadly neutralizing antibodies against influenza A viruses has raised hopes for the development of monoclonal antibody—based immunotherapy…”
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SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo by Hui, Kenrie P. Y., Ho, John C. W., Cheung, Man-chun, Ng, Ka-chun, Ching, Rachel H. H., Lai, Ka-ling, Kam, Tonia Tong, Gu, Haogao, Sit, Ko-Yung, Hsin, Michael K. Y., Au, Timmy W. K., Poon, Leo L. M., Peiris, Malik, Nicholls, John M., Chan, Michael C. W.

“…The emergence of SARS-CoV-2 variants of concern with progressively increased transmissibility between humans is a threat to global public health. The Omicron…”
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ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection by Hachim, Asmaa, Kavian, Niloufar, Cohen, Carolyn A., Chin, Alex W. H., Chu, Daniel K. W., Mok, Chris K. P., Tsang, Owen T. Y., Yeung, Yiu Cheong, Perera, Ranawaka A. P. M., Poon, Leo L. M., Peiris, J. S. Malik, Valkenburg, Sophie A.

“…The SARS-CoV-2 virus emerged in December 2019 and has caused a worldwide pandemic due to the lack of any pre-existing immunity. Accurate serology testing is…”
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A Push for Real Normal: Mass Screening for COVID-19 by Poon, Leo L M

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A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses by Ekiert, Damian C., Friesen, Robert H. E., Bhabha, Gira, Kwaks, Ted, Jongeneelen, Mandy, Yu, Wenli, Ophorst, Carla, Cox, Freek, Korse, Hans J.W.M., Brandenburg, Boerries, Vogels, Ronald, Brakenhoff, Just P.J., Kompier, Ronald, Koldijk, Martin H., Cornelissen, Lisette A.H.M., Poon, Leo L. M., Peiris, Malik, Koudstaal, Wouter, Wilson, Ian A., Goudsmit, Jaap

“…Current flu vaccines provide only limited coverage against seasonal strains of influenza viruses. The identification of V H 1-69 antibodies that broadly…”
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Viral dynamics in mild and severe cases of COVID-19 by Liu, Yang, Yan, Li-Meng, Wan, Lagen, Xiang, Tian-Xin, Le, Aiping, Liu, Jia-Ming, Peiris, Malik, Poon, Leo L M, Zhang, Wei

“…Patients who had any of the following features at the time of, or after, admission were classified as severe cases: (1) respiratory distress (≥30 breaths per…”
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Effect of moist heat reprocessing of N95 respirators on SARS-CoV-2 inactivation and respirator function by Daeschler, Simeon C, Manson, Niclas, Joachim, Kariym, Chin, Alex W H, Chan, Katelyn, Chen, Paul Z, Tajdaran, Kiana, Mirmoeini, Kaveh, Zhang, Jennifer J, Maynes, Jason T, Zhang, Libo, Science, Michelle, Darbandi, Ali, Stephens, Derek, Gu, Frank, Poon, Leo L M, Borschel, Gregory H

“…Unprecedented demand for N95 respirators during the coronavirus disease 2019 (COVID-19) pandemic has led to a global shortage of these masks. We validated a…”
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MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea, 2015 by Choe, Pyoeng Gyun, Perera, R A P M, Park, Wan Beom, Song, Kyoung-Ho, Bang, Ji Hwan, Kim, Eu Suk, Kim, Hong Bin, Ko, Long Wei Ronald, Park, Sang Won, Kim, Nam-Joong, Lau, Eric H Y, Poon, Leo L M, Peiris, Malik, Oh, Myoung-Don

“…We investigated the kinetics of the Middle East respiratory syndrome coronavirus (MERS-CoV) neutralizing and spike protein antibody titers over the course of 1…”
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Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters by Burckhardt, Rachel M, Dennehy, John J, Poon, Leo L M, Saif, Linda J, Enquist, Lynn W

“…Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for…”
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The first 2019 novel coronavirus case in Nepal by Bastola, Anup, Sah, Ranjit, Rodriguez-Morales, Alfonso J, Lal, Bibek Kumar, Jha, Runa, Ojha, Hemant Chanda, Shrestha, Bikesh, Chu, Daniel K W, Poon, Leo L M, Costello, Anthony, Morita, Kouichi, Pandey, Basu Dev

“…In January, 2020, the outbreak of the 2019 novel coronavirus (2019-nCoV) in China spread progressively to other countries,1,2 with WHO declaring it a Public…”
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