Search Results - "Poon, K K"

Self-reported Antibiotic Allergy Incidence and Prevalence: Age and Sex Effects by Macy, Eric, MD, Poon K-Y, T., MS

“…Abstract Background Data on the prevalence and incidence of adverse reactions to antibiotics in outpatient populations are rare. These events are commonly…”
Get full text

Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris by Caruso, Sarah, Poon, Ivan K H

“…The many functions of extracellular vesicles (EVs) like exosomes and microvesicles released from healthy cells have been well characterized, particularly in…”
Get full text

Towards a Unified Description of the Rheology of Hard-Particle Suspensions by Guy, B M, Hermes, M, Poon, W C K

“…The rheology of suspensions of Brownian, or colloidal, particles (diameter d≲1  μm) differs markedly from that of larger grains (d≳50  μm). Each of these two…”
Get full text

Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis by Paone, Stephanie, Baxter, Amy A., Hulett, Mark D., Poon, Ivan K. H.

“…To maintain physiological homeostasis, cell turnover occurs every day in the body via a form of programmed cell death called apoptosis. During apoptosis, cells…”
Get full text

New tools for the analysis and validation of cryo‐EM maps and atomic models by Afonine, Pavel V., Klaholz, Bruno P., Moriarty, Nigel W., Poon, Billy K., Sobolev, Oleg V., Terwilliger, Thomas C., Adams, Paul D., Urzhumtsev, Alexandre

“…Recent advances in the field of electron cryomicroscopy (cryo‐EM) have resulted in a rapidly increasing number of atomic models of biomacromolecules that have…”
Get full text

Polder maps: improving OMIT maps by excluding bulk solvent by Liebschner, Dorothee, Afonine, Pavel V., Moriarty, Nigel W., Poon, Billy K., Sobolev, Oleg V., Terwilliger, Thomas C., Adams, Paul D.

“…The crystallographic maps that are routinely used during the structure‐solution workflow are almost always model‐biased because model information is used for…”
Get full text

Hydrodynamic and Contact Contributions to Continuous Shear Thickening in Colloidal Suspensions by Lin, Neil Y C, Guy, Ben M, Hermes, Michiel, Ness, Chris, Sun, Jin, Poon, Wilson C K, Cohen, Itai

“…Shear thickening is a widespread phenomenon in suspension flow that, despite sustained study, is still the subject of much debate. The longstanding view that…”
Get full text

Painting with light-powered bacteria by Arlt, Jochen, Martinez, Vincent A., Dawson, Angela, Pilizota, Teuta, Poon, Wilson C. K.

“…Self-assembly is a promising route for micro- and nano-fabrication with potential to revolutionise many areas of technology, including personalised medicine…”
Get full text

A growing bacterial colony in two dimensions as an active nematic by Dell’Arciprete, D., Blow, M. L., Brown, A. T., Farrell, F. D. C., Lintuvuori, J. S., McVey, A. F., Marenduzzo, D., Poon, W. C. K.

“…How a single bacterium becomes a colony of many thousand cells is important in biomedicine and food safety. Much is known about the molecular and genetic bases…”
Get full text

DNA is an antimicrobial component of neutrophil extracellular traps by Halverson, Tyler W R, Wilton, Mike, Poon, Karen K H, Petri, Björn, Lewenza, Shawn

“…Neutrophil extracellular traps (NETs) comprise an ejected lattice of chromatin enmeshed with granular and nuclear proteins that are capable of capturing and…”
Get full text

Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4 by Goodall, Katharine J, Poon, Ivan K H, Phipps, Simon, Hulett, Mark D

“…Heparanase is a β-D-endoglucuronidase that cleaves heparan sulfate (HS), facilitating degradation of the extracellular matrix (ECM) and the release of HS-bound…”
Get full text

Unexpected link between an antibiotic, pannexin channels and apoptosis by Poon, Ivan K. H., Chiu, Yu-Hsin, Armstrong, Allison J., Kinchen, Jason M., Juncadella, Ignacio J., Bayliss, Douglas A., Ravichandran, Kodi S.

“…Plasma membrane pannexin 1 channels (PANX1) release nucleotide find-me signals from apoptotic cells to attract phagocytes. Here we show that the quinolone…”
Get full text

Flagellated bacterial motility in polymer solutions by Martinez, Vincent A., Schwarz-Linek, Jana, Reufer, Mathias, Wilson, Laurence G., Morozov, Alexander N., Poon, Wilson C. K.

“…Significance The way microorganisms swim in concentrated polymer solutions has important biomedical implications, i.e., how pathogens invade the mucosal lining…”
Get full text

Constraint-Based Approach to Granular Dispersion Rheology by Guy, B M, Richards, J A, Hodgson, D J M, Blanco, E, Poon, W C K

“…We present a phenomenological model for granular suspension rheology in which particle interactions enter as constraints to relative particle motion. By…”
Get full text

Phase separation and rotor self-assembly in active particle suspensions by Schwarz-Linek, J, Valeriani, C, Cacciuto, A, Cates, M. E, Marenduzzo, D, Morozov, A. N, Poon, W. C. K

“…Adding a nonadsorbing polymer to passive colloids induces an attraction between the particles via the "depletion" mechanism. High enough polymer concentrations…”
Get full text

Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects by Baxter, Amy A., Lay, Fung T., Poon, Ivan K. H., Kvansakul, Marc, Hulett, Mark D.

“…There is an ongoing need for effective and targeted cancer treatments that can overcome the detrimental side effects presented by current treatment options…”
Get full text

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis by Samuel, Monisha, Fonseka, Pamali, Sanwlani, Rahul, Gangoda, Lahiru, Chee, Sing Ho, Keerthikumar, Shivakumar, Spurling, Alex, Chitti, Sai V., Zanker, Damien, Ang, Ching-Seng, Atukorala, Ishara, Kang, Taeyoung, Shahi, Sanjay, Marzan, Akbar L., Nedeva, Christina, Vennin, Claire, Lucas, Morghan C., Cheng, Lesley, Herrmann, David, Pathan, Mohashin, Chisanga, David, Warren, Sean C., Zhao, Kening, Abraham, Nidhi, Anand, Sushma, Boukouris, Stephanie, Adda, Christopher G., Jiang, Lanzhou, Shekhar, Tanmay M., Baschuk, Nikola, Hawkins, Christine J., Johnston, Amelia J., Orian, Jacqueline Monique, Hoogenraad, Nicholas J., Poon, Ivan K., Hill, Andrew F., Jois, Markandeya, Timpson, Paul, Parker, Belinda S., Mathivanan, Suresh

“…The concept that extracellular vesicles (EVs) from the diet can be absorbed by the intestinal tract of the consuming organism, be bioavailable in various…”
Get full text

Apoptotic cell clearance: basic biology and therapeutic potential by Poon, Ivan K. H., Lucas, Christopher D., Rossi, Adriano G., Ravichandran, Kodi S.

“…Key Points Apoptotic cells are rapidly removed by tissue-resident professional phagocytes and/or by neighbouring non-professional phagocytes under homeostatic…”
Get full text

Detecting recurrent passenger mutations in melanoma by targeted UV damage sequencing by Selvam, Kathiresan, Sivapragasam, Smitha, Poon, Gregory M. K., Wyrick, John J.

“…Sequencing of melanomas has identified hundreds of recurrent mutations in both coding and non-coding DNA. These include a number of well-characterized…”
Get full text

Monolithically integrated, broadband, high-efficiency silicon nitride-on-silicon waveguide photodetectors in a visible-light integrated photonics platform by Lin, Yiding, Yong, Zheng, Luo, Xianshu, Azadeh, Saeed Sharif, Mikkelsen, Jared C., Sharma, Ankita, Chen, Hong, Mak, Jason C. C., Lo, Patrick Guo-Qiang, Sacher, Wesley D., Poon, Joyce K. S.

“…Visible and near-infrared spectrum photonic integrated circuits are quickly becoming a key technology to address the scaling challenges in quantum information…”
Get full text