Search Results - "Poon, Gladys Y P"

The evolutionary dynamics and fitness landscape of clonal hematopoiesis by Watson, Caroline J, Papula, A L, Poon, Gladys Y P, Wong, Wing H, Young, Andrew L, Druley, Todd E, Fisher, Daniel S, Blundell, Jamie R

“…Somatic mutations acquired in healthy tissues as we age are major determinants of cancer risk. Whether variants confer a fitness advantage or rise to…”
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Synonymous mutations reveal genome-wide levels of positive selection in healthy tissues by Poon, Gladys Y. P., Watson, Caroline J., Fisher, Daniel S., Blundell, Jamie R.

“…Genetic alterations under positive selection in healthy tissues have implications for cancer risk. However, total levels of positive selection across the…”
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