Search Results - "Poon, C M"

Guidelines for the management of hemophilia by Srivastava, A., Brewer, A. K., Mauser-Bunschoten, E. P., Key, N. S., Kitchen, S., Llinas, A., Ludlam, C. A., Mahlangu, J. N., Mulder, K., Poon, M. C., Street, A.

“…Summary Hemophilia is a rare disorder that is complex to diagnose and to manage. These evidence‐based guidelines offer practical recommendations on the…”
Get full text

Management of hepatocellular carcinoma with portal vein tumor thrombosis: Review and update at 2016 by Chan, Stephen L, Chong, Charing C N, Chan, Anthony W H, Poon, Darren M C, Chok, Kenneth S H

“…Portal vein tumor thrombosis(PVTT) is a common phenomenon in hepatocellular carcinoma(HCC). Compared to HCC without PVTT, HCC with PVTT is characterized by an…”
Get full text

Musculoskeletal health of subjects with hemophilia A treated with tailored prophylaxis: Canadian Hemophilia Primary Prophylaxis (CHPS) Study by Hilliard, P., Zourikian, N., Blanchette, V., Chan, A., Elliott, B., Israels, S. J., Nilson, J., Poon, M.‐C., Laferriere, N., Van Neste, C., Jarock, C., Wu, J., McLimont, M., Feldman, B.

“…Summary Background Full‐dose prophylaxis is very effective at minimizing joint damage but is costly. Tailored prophylaxis has been proposed as a way of…”
Get full text

Low dose secondary prophylaxis reduces joint bleeding in severe and moderate haemophilic children: a pilot study in China by WU, R., LUKE, K.-H., POON, M.-C., WU, X., ZHANG, N., ZHAO, L., SU, Y., ZHANG, J.

“…The most common bleeding in haemophilic patients is in joints, and joint disability is the most common complications in these patients receiving inadequate…”
Get full text

Short-term low-dose secondary prophylaxis for severe/moderate haemophilia A children is beneficial to reduce bleed and improve daily activity, but there are obstacle in its execution: a multi-centre pilot study in China by Tang, L., Wu, R., Sun, J., Zhang, X., Feng, X., Luke, K.-H., Poon, M.-C.

“…Summary We recently showed in a single centre trial that low‐dose secondary prophylaxis in severe/moderate haemophilia patients with arthropathy is feasible…”
Get full text

Cardiovascular disease (CVD) in Canadians with haemophilia: Age-Related CVD in Haemophilia Epidemiological Research (ARCHER study) by Minuk, L., Jackson, S., Iorio, A., Poon, M.-C., Dilworth, E., Brose, K., Card, R., Rizwan, I., Chin-Yee, B., Louzada, M.

“…Introduction Improvements in haemophilia care have increased life expectancy in persons with haemophilia (PWH). This ageing population presents clinicians with…”
Get full text

Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study by FELDMAN, B. M., PAI, M., RIVARD, G. E., ISRAELS, S., POON, M.‐C., DEMERS, C., ROBINSON, S., LUKE, K.‐H., WU, J. K. M., GILL, K., LILLICRAP, D., BABYN, P., MCLIMONT, M., BLANCHETTE, V. S.

“…Background: Prophylactic treatment for severe hemophilia A is likely to be more effective than treatment when bleeding occurs, however, prophylaxis is costly…”
Get full text

Chinese Hemophilia Joint Health Score 2.1 reliability study by Sun, J., Hilliard, P. E., Feldman, B. M., Zourikian, N., Chen, L., Blanchette, V. S., Luke, K. H., Poon, M-C.

“…Summary To meet the rapidly expanding need for musculoskeletal (MSK) specialists [physiotherapists (PTs), physiatrists] in haemophilia care in China, a 4‐day…”
Get full text

Fracture risk in patients with haemophilia by Khanna, P., Lee, A., Poon, M.-C.

Get full text

Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach by Lane, S. J., Walker, I., Chan, A. K., Heddle, N. M., Poon, M.-C., Minuk, L., Jardine, L., Arnold, E., Sholapur, N., Webert, K. E.

“…Summary The first generation of young men using primary prophylaxis is coming of age. Important questions regarding the management of severe haemophilia with…”
Get full text

Coexisting congenital dysfibrinogenemia with a novel mutation in fibrinogen γ chain (γ322 Phe→Ile, Fibrinogen Beijing) and haemophilia B in a family by Hua, B., Li, K., Lee, A., Poon, M.-C., Zhao, Y.

“…Introduction Both congenital dysfibrinogenemia and haemophilia B (HB) are rare coagulopathies caused by mutations within the fibrinogen and F9 genes…”
Get full text

Low‐dose factor VIII infusion in Chinese adult haemophilia A patients: pharmacokinetics evidence that daily infusion results in higher trough level than with every‐other‐day infusion with similar factor VIII consumption by Hua, B., Lee, A., Fan, L., Li, K., Zhang, Y., Poon, M.‐C., Zhao, Y.

“…Introduction Pharmacokinetics (PK) modelling suggests improvement of trough levels are achieved by using more frequent infusion strategy. However, no clinical…”
Get full text

Editorial for “Multi‐site concordance of diffusion weighted imaging quantification for assessing prostate cancer aggressiveness” by Yuan, Jing, Poon, Darren M.C., Lo, Gladys

Get full text

A prospective study of health‐related quality of life of boys with severe haemophilia A in China: comparing on‐demand to prophylaxis treatment by Wu, R., Sun, J., Xiao, J., Liu, Y., Xue, F., Wang, H., Tang, L., Zhao, Y., Li, K., Yang, R., Hu, Y., Luke, K.‐H., Poon, M.‐C., Blanchette, V. S., Usuba, K., Young, N. L.

“…Introduction Treatment for boys with haemophilia in China is rapidly improving; however, comprehensive outcomes have not been examined prospectively. Aim The…”
Get full text

Adult males with haemophilia have a different macrovascular and microvascular endothelial function profile compared with healthy controls by Sun, H., Yang, M., Fung, M., Chan, S., Jawi, M., Anderson, T., Poon, M.‐C., Jackson, S.

“…Introduction Endothelial function has been identified as an independent predictor of cardiovascular risk in the general population. It is unclear if the…”
Get full text

Validation of the Chinese version of the Canadian Haemophilia Outcomes-Kids' Life Assessment Tool (the CHO-KLAT) by Wu, R., Zhang, J., Sun, J., Zhou, M., Wu, J. S., Li, N., Li, X., Luke, K. H., Poon, M.-C., Blanchette, V. S., Young, N. L.

“…Summary It is important to assess the health‐related quality of life outcomes of boys in China, but there are no tools validated for this purpose. The…”
Get full text

Suspected collagen disorders in the bleeding disorder clinic: A case-control study by Jackson, S. C., Odiaman, L., Card, R. T., van der Bom, J. G., Poon, M-C.

“…Summary Disorders of collagen are associated with a mild bleeding tendency because of the potential abnormal interaction of collagen, von Willebrand factor…”
Get full text

Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China by Li, Z., Wu, J., Zhao, Y., Liu, R., Li, K., Zhou, Y., Wu, R., Yang, R., Zhang, X., Lian, S., Hu, Q., Li, X., Gu, J., Zhou, R., Sun, J., Li, C., Xu, W., Poon, M.‐C., Xiao, J.

“…Objective To explore the influence of medical insurance policy and charity assistance projects on the uptake and discontinuation of regular prophylaxis…”
Get full text

Experience with central venous access devices (CVADs) in the Canadian hemophilia primary prophylaxis study (CHPS) by Langley, A. R., Stain, A. M., Chan, A., McLimont, M., Chait, S., Wu, J., Poon, M.-C., Card, R., Israels, S. J., Laferriere, N., Klaassen, R. J., Rivard, G. E., Cloutier, S., Hawes, S., Feldman, B., Blanchette, V.

“…Introduction Haemophilia A treatment with factor VIII concentrates requires frequent venipunctures; a central venous access device (CVAD) may be required to…”
Get full text

Evaluation of the Reliability and the Performance of Magnetic Resonance Imaging Radiomics in the Presence of Randomly Generated Irrelevant Features for Prostate Cancer by Xue, Cindy, Yuan, Jing, Lo, Gladys G, Poon, Darren M C, Chu, Winnie C W

“…Radiomics has the potential to aid prostate cancer (PC) diagnoses and prediction by analyzing and modeling quantitative features extracted from clinical…”
Get full text