Search Results - "Poole, James C."

Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-D3) dilution in rats by Stimpson, Stephen A, Turner, Scott M, Clifton, Lisa G, Poole, James C, Mohammed, Hussein A, Shearer, Todd W, Waitt, Greg M, Hagerty, Laura L, Remlinger, Katja S, Hellerstein, Marc K, Evans, William J

“…There is currently no direct, facile method to determine total-body skeletal muscle mass for the diagnosis and treatment of skeletal muscle wasting conditions…”
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Longitudinal changes in total body creatine pool size and skeletal muscle mass using the D3-creatine dilution method by Stimpson, Stephen A., Leonard, Michael S., Clifton, Lisa G., Poole, James C., Turner, Scott M., Shearer, Todd W., Remlinger, Katja S., Clark, Richard V., Hellerstein, Marc K., Evans, William J.

“…Background We recently validated in cross-sectional studies a new method to determine total body creatine pool size and skeletal muscle mass based on D 3…”
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Longitudinal changes in total body creatine pool size and skeletal muscle mass using the D 3 -creatine dilution method by Stimpson, Stephen A, Leonard, Michael S, Clifton, Lisa G, Poole, James C, Turner, Scott M, Shearer, Todd W, Remlinger, Katja S, Clark, Richard V, Hellerstein, Marc K, Evans, William J

“…We recently validated in cross-sectional studies a new method to determine total body creatine pool size and skeletal muscle mass based on D -creatine dilution…”
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Longitudinal determination of total body creatine pool size and skeletal muscle mass in rats by D 3 ‐creatine dilution by Stimpson, Stephen A., Leonard, Michael S., Clifton, Lisa G., Poole, James C., Turner, Scott M., Shearer, Todd W., Remlinger, Katja S., Clark, Richard V., Hellerstein, Marc K., Evans, William J.

“…Abstract only We recently described a new method to determine total body creatine pool size and skeletal muscle mass based on dilution of an oral dose of D 3…”
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Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-d3) dilution in rats by STIMPSON, Stephen A, TURNER, Scott M, EVANS, William J, CLIFTON, Lisa G, POOLE, James C, MOHAMMED, Hussein A, SHEARER, Todd W, WAITT, Greg M, HAGERTY, Laura L, REMLINGER, Katja S, HELLERSTEIN, Marc K

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Disposition kinetics of ML-1035 sulfoxide enantiomers and the prochiral sulfide in rats by Kuo, B S, Poole, J C, Mandagere, A K, Hwang, K K

“…ML-1035, 4-amino-5-chloro-2-[2-(methylsulfinyl)ethoxy]-N-[2- (diethyl-amino)ethyl]benzamide, is a sulfoxide compound and a racemic gastroprokinetic agent with…”
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Validation of a column-switching high-performance liquid chromatographic (HPLC) method for determination of ML-1035 and its five metabolites in plasma by Kuo, B S, Poole, J C, Hwang, K K

“…A fully automated column-switching HPLC procedure has been developed and validated for quantitation of ML-1035 and its five metabolites in plasma employing…”
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Determination of bioavailability and systemically available fractions of drugs undergoing reversible metabolism: application to 4-amino-5-chloro-2-[2-(methylsulfinyl)ethoxy]-N-[2- (diethylamino)ethyl]benzamide and its sulfide and sulfone metabolites in rats by Kuo, B S, Poole, J C, Hwang, K K, Cheng, H

“…Methods are discussed which permit the calculation of the bioavailability (F) and fraction of an oral dose entering the central circulation (f) of a drug and…”
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Pharmacokinetics and metabolic interconversion of intravenous 4-amino-5-chloro-2-[(methylsulfinyl)ethoxy]-N-[2-(diethylamino)ethyl] benzamide and its sulfide and sulfone metabolites in rats by Kuo, B S, Poole, J C, Hwang, K K, Cheng, H

“…The pharmacokinetics of a new 5-hydroxytryptamine (5HT3) receptor antagonist, 4-amino-5-chloro-2-[(methylsulfinyl)ethoxy]-N-[2-(diethylamino)ethyl] benzamide…”
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Column-switching liquid chromatographic determination of ML-1035 sulphoxide and its sulphone and sulphide metabolites in rat urine by Kuo, B S, Poole, J C, Mandagere, A, Hwang, K K

“…A fully automated column-switching LC assay has been developed for the simultaneous determination of a gastroprokinetic agent, ML-1035 sulphoxide, and its…”
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