Search Results - "Poole, Amy V"
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Precision Medicine and the Role of Biomarkers of Radiotherapy Response in Breast Cancer
Published in Frontiers in oncology (24-04-2020)“…Radiotherapy remains an important treatment modality in nearly two thirds of all cancers, including the primary curative or palliative treatment of breast…”
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Chloride co‐transporters as possible therapeutic targets for stroke
Published in Journal of neurochemistry (01-01-2017)“…Stroke is one of the major causes of death and disability worldwide. The major type of stroke is an ischaemic one, which is caused by a blockage that…”
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Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia
Published in PloS one (02-10-2017)“…Stroke causes severe neuronal damage as disrupted cerebral blood flow starves neurons of oxygen and glucose. The hypoxia inducible factors (HIF-1α and HIF-2α)…”
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4
hASH1 nuclear localization persists in neuroendocrine transdifferentiated prostate cancer cells, even upon reintroduction of androgen
Published in Scientific reports (13-12-2019)“…Neuroendocrine prostate cancer (NEPC) is thought to arise as prostate adenocarcinoma cells transdifferentiate into neuroendocrine (NE) cells to escape potent…”
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GABA(A) receptor chloride channels are involved in the neuroprotective role of GABA following oxygen and glucose deprivation in the rat cerebral cortex but not in the hippocampus
Published in Brain research (02-10-2013)“…Assays on "ex vivo" sections of rat hippocampus and rat cerebral cortex, subjected to oxygen and glucose deprivation (OGD) and a three-hour reperfusion-like…”
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GABAA receptor chloride channels are involved in the neuroprotective role of GABA following oxygen and glucose deprivation in the rat cerebral cortex but not in the hippocampus
Published in Brain research (02-10-2013)“…Abstract Assays on “ex vivo” sections of rat hippocampus and rat cerebral cortex, subjected to oxygen and glucose deprivation (OGD) and a three-hour…”
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Preferential activation of HIF-2[alpha] adaptive signalling in neuronal-like cells in response to acute hypoxia
Published in PloS one (02-10-2017)“…Stroke causes severe neuronal damage as disrupted cerebral blood flow starves neurons of oxygen and glucose. The hypoxia inducible factors (HIF-1[alpha] and…”
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Journal Article