Search Results - "Pool, Lieneke"
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Tolerogenic dendritic cells generated in vitro using a novel protocol mimicking mucosal tolerance mechanisms represent a potential therapeutic cell platform for induction of immune tolerance
Published in Frontiers in immunology (2023)“…Dendritic cells (DCs) are mediators between innate and adaptive immunity and vital in initiating and modulating antigen-specific immune responses. The most…”
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Deletion of IRF4 in Dendritic Cells Leads to Delayed Onset of T Cell-Dependent Colitis
Published in The Journal of immunology (1950) (15-02-2020)“…Classical dendritic cells (cDC) can be classified into two major subsets: Irf8-dependent cDC1 and Irf4-expressing cDC2. Although these subsets play distinct…”
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IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis
Published in Immunity (Cambridge, Mass.) (19-04-2016)“…The role of dendritic cells (DCs) in intestinal immune homeostasis remains incompletely defined. Here we show that mice lacking IRF8…”
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IL-18Rα-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness
Published in European journal of immunology (01-06-2016)“…IL-18 has been implicated in inflammatory bowel disease (IBD), however its role in the regulation of intestinal CD4(+) T-cell function remains unclear. Here we…”
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IL‐18Rα‐deficient CD4+ T cells induce intestinal inflammation in the CD45RBhi transfer model of colitis despite impaired innate responsiveness
Published in European journal of immunology (01-06-2016)“…IL‐18 has been implicated in inflammatory bowel disease (IBD), however its role in the regulation of intestinal CD4+ T‐cell function remains unclear. Here we…”
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IL-18R[alpha]-deficient CD4+ T cells induce intestinal inflammation in the CD45RBhi transfer model of colitis despite impaired innate responsiveness
Published in European journal of immunology (01-06-2016)“…IL-18 has been implicated in inflammatory bowel disease (IBD), however its role in the regulation of intestinal CD4+ T-cell function remains unclear. Here we…”
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Journal Article -
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IL-18R alpha -deficient CD4 super(+) T cells induce intestinal inflammation in the CD45RB super(hi) transfer model of colitis despite impaired innate responsiveness
Published in European journal of immunology (01-06-2016)“…IL-18 has been implicated in inflammatory bowel disease (IBD), however its role in the regulation of intestinal CD4 super(+) T-cell function remains unclear…”
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Journal Article -
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IL‐18Rα‐deficient CD4 + T cells induce intestinal inflammation in the CD45RB hi transfer model of colitis despite impaired innate responsiveness
Published in European journal of immunology (01-06-2016)“…IL‐18 has been implicated in inflammatory bowel disease (IBD), however its role in the regulation of intestinal CD4 + T‐cell function remains unclear. Here we…”
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