Search Results - "Pool, Chris W"

Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons by Mason, Matthew RJ, Ehlert, Erich ME, Eggers, Ruben, Pool, Chris W, Hermening, Stephan, Huseinovic, Angelina, Timmermans, Eric, Blits, Bas, Verhaagen, Joost

“…For many experiments in the study of the peripheral nervous system, it would be useful to genetically manipulate primary sensory neurons. We have compared…”
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Differential effects of lentiviral vector-mediated overexpression of nerve growth factor and glial cell line-derived neurotrophic factor on regenerating sensory and motor axons in the transected peripheral nerve by Tannemaat, Martijn R., Eggers, Ruben, Hendriks, William T., De Ruiter, Godard C. W., Van Heerikhuize, Joop J., Pool, Chris W., Malessy, Martijn J. A., Boer, Gerard J., Verhaagen, Joost

“…Even after reconstructive surgery, major functional impairments remain in the majority of patients with peripheral nerve injuries. The application of novel…”
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Neuroregenerative effects of lentiviral vector-mediated GDNF expression in reimplanted ventral roots by Eggers, Ruben, Hendriks, William T.J., Tannemaat, Martijn R., van Heerikhuize, Joop J., Pool, Chris W., Carlstedt, Thomas P., Zaldumbide, Arnaud, Hoeben, Rob C., Boer, Gerard J., Verhaagen, Joost

“…Traumatic avulsion of spinal nerve roots causes complete paralysis of the affected limb. Reimplantation of avulsed roots results in only limited functional…”
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Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury by Ruitenberg, Marc J, Blits, Bas, Dijkhuizen, Paul A, te Beek, Erik T, Bakker, Arne, van Heerikhuize, Joop J, Pool, Chris W, Hermens, Wim T.J, Boer, Gerard J, Verhaagen, Joost

“…Rubrospinal neurons (RSNs) undergo marked atrophy after cervical axotomy. This progressive atrophy may impair the regenerative capacity of RSNs in response to…”
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3-D Cytoarchitectonic parcellation of human orbitofrontal cortex by Uylings, Harry B.M, Arigita, Ernesto J. Sanz, de Vos, Koos, Pool, Chris W, Evers, Paul, Rajkowska, Grazyna

“…Abstract The orbitofrontal cortex (OFC) is located on the basal surface of the frontal lobe and is distinguished by its unique anatomical and functional…”
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3-D cytoarchitectonic parcellation of human orbitofrontal cortex correlation with postmortem MRI by Uylings, Harry B M, Sanz-Arigita, Ernesto J, de Vos, Koos, Pool, Chris W, Evers, Paul, Rajkowska, Grazyna

“…The orbitofrontal cortex (OFC) is located on the basal surface of the frontal lobe and is distinguished by its unique anatomical and functional features…”
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Image analyser-assisted morphometry of the locus coeruleus in Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis by Hoogendijk, W J, Pool, C W, Troost, D, van Zwieten, E, Swaab, D F

“…Several observations suggest that neuronal shrinkage rather than cell death is the major phenomenon in neurodegenerative diseases. In order to make this…”
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Double Immunolabeling of Neuropeptides in the Human Hypothalamus as Analyzed by Confocal Laser Scanning Fluorescence Microscopy by Romijn, Herms J, van Uum, Johanna F.M, Breedijk, Ingrid, Emmering, Jasper, Radu, Ioan, Pool, Chris W

“…The main goal of this study was to develop a better light microscopic procedure for quantitative study of the cellular co-localization of neuropeptides in…”
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Overlay of conventional angiographic and en-face OCT images enhances their interpretation by van Velthoven, Mirjam E J, de Vos, Koos, Verbraak, Frank D, Pool, Chris W, de Smet, Marc D

“…Combining characteristic morphological and functional information in one image increases pathophysiologic understanding as well as diagnostic accuracy in most…”
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Male-to-Female Transsexuals Have Female Neuron Numbers in a Limbic Nucleus by Kruijver, Frank P. M., Zhou, Jiang-Ning, Pool, Chris W., Hofman, Michel A., Gooren, Louis J. G., Swaab, Dick F.

“…Transsexuals experience themselves as being of the opposite sex, despite having the biological characteristics of one sex. A crucial question resulting from a…”
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Lack of Association Between Depression and Loss of Neurons in the Locus Coeruleus in Alzheimer Disease by Hoogendijk, Witte J. G, Sommer, Iris E. C, Pool, Chris W, Kamphorst, Wouter, Hofman, Michel A, Eikelenboom, Piet, Swaab, Dick F

“…BACKGROUND Depression, one of the most frequent psychiatric disturbances in Alzheimer disease (AD), is proposed to have its neurobiological basis in neuron…”
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Decreased Hippocampal Metabolic Activity in Alzheimer Patients Is Not Reflected in the Immunoreactivity of Cytochrome Oxidase Subunits by Verwer, Ronald W.H., Jansen, Karen A., Sluiter, Arja A., Pool, Chris W., Kamphorst, Wouter, Swaab, Dick F.

“…In the present study we have compared histochemically determined cytochrome oxidase activity with the levels of immunocytochemically stained cytochrome oxidase…”
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Modulatory role of catecholamines in the transsynaptic expression of c- fos in the rat medial prefrontal cortex induced by disinhibition of the mediodorsal thalamus: a study employing microdialysis and immunohistochemistry by Bubser, Michael, Feenstra, Matthijs G.P., Erdtsieck-Ernste, Erna B.H.W., Botterblom, Margriet H.A., Van Uum, Hannie F.M., Pool, Chris W.

“…We studied the interaction of catecholaminergic and thalamic afferents of the medial prefrontal cortex (PFC) by analyzing the effects of catecholamine…”
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Immunochemical detection of peptides and proteins on press-blots after direct tissue gel isoelectric focusing by van der Sluis, P J, Pool, C W, Sluiter, A A

“…A sensitive method is described for the detection of tissue peptides and proteins. They are separated by tissue isoelectric focusing using thin large-pore…”
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Immunohistochemical detection of O6-ethyldeoxyguanosine in the rat brain after in vivo applications of N-ethyl-N-nitrosourea by Heyting, C, Van der Laken, C J, Raamsdonk, W V, Pool, C W

“…An immunohistochemical procedure was developed which allows the localization of the DNA lesion O6-ethyldeoxyguanosine (O6-EtdGuo) within tissues and organs…”
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